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Targeted anti-tumor and anti-cancer agent and preparation method thereof

An anti-tumor, targeted technology, applied in the direction of anti-tumor drugs, pharmaceutical formulations, drug combinations, etc., can solve problems such as poor curative effect, no obvious breakthrough in treatment, and large toxic and side effects, so as to enhance normal heart contraction and skin circulation. Prosperity, enhance immune function effect

Active Publication Date: 2015-09-30
何忠琳
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, to this day, cancer is still a worldwide problem. Countries around the world are exploring, researching and developing anti-cancer drugs. Every year, many new anti-cancer drugs come out, but these drugs generally have poor curative effect and severe side effects. A variety of problems, there is still no obvious breakthrough in treatment

Method used

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  • Targeted anti-tumor and anti-cancer agent and preparation method thereof
  • Targeted anti-tumor and anti-cancer agent and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0095] A targeted anti-tumor and anti-cancer drug, the components of which are (weight %) 57 kg of pseudo-black spiny ants, 28.5 kg of placenta, 14.3 kg of astragalus, 0.13 kg of cordycepin and 0.07 kg of Corydalis.

[0096] The extraction and preparation methods of each single drug of the present invention are described below as follows:

[0097] Pseudo-black spiny ants: excavate and wash wild organisms above 3,500 meters above sea level in the west in spring, summer and autumn → let them die after 7 days of biotechnology rearing in pure water → dry in the sun or at 60°C for 7 hours → store in refrigerator for later use → Take 57kg of pseudo-black spiny ants from the refrigerator → pulverize → screen dry powder through 24 mesh → dry powder is placed in CO extractor → adjust the extraction solvent flow rate to 15L / h → extraction pressure 30MPa → temperature is 60 ℃ for 3 hours → collected for extraction Separation of petroleum ether at 80°C→collect the separated liquid and hea...

example 1

[0105] The present invention is suitable for various clinical stages in various stages, such as patients who are unwilling to undergo surgery, patients who have lost the opportunity for surgery, and patients after surgery, for the treatment of early, middle and late stage cancers. Especially: lung cancer, liver cancer, breast cancer, esophageal cancer, urinary system tumors, gynecological tumors and other very significant effects. Example 1: Xie, male, 66 years old, a patient with liver cancer, went to Beijing PLA 301 General Hospital in 2005 for a CT scan. The results of the report showed that irregular lumps with increased radioactive uptake were seen in the liver, with a maximum SUV of 16.81 , an average of 7.56, the maximum SUV of delayed imaging was 16.52, an average of 7.65, the radioactive uptake was uneven, and the center was a non-dead area with radioactive defects; the density of the corresponding parts of the same machine was unevenly reduced, and 3 to 4 slightly low...

Embodiment 2

[0110] The targeted anti-tumor and anti-cancer agent in this example is prepared by using pseudo-black spiny ants, placenta, astragalus, cordycepin, and Corydalis Corydalis as raw materials. , Hengqi 14kg, Cordycepin 0.13kg, Corydalis 0.07kg;

[0111] First of all, the refinement and extraction of the raw material single drug and its related technical methods are as follows:

[0112] ①Pseudo-black spiny ants: In spring, summer, and autumn, excavate wild organisms above 3,500 meters above sea level in the west, wash them → let them die after 7 days of biotechnology rearing in pure water → dry them in the sun or at 60°C for 7 hours → store in the refrigerator for later use → Take 57.8kg of pseudo-black spiny ants from the refrigerator → pulverize → screen dry powder through 24 meshes → put the dry powder in a CO extractor → adjust the extraction solvent flow rate to 15L / h → extraction pressure 30MPa → temperature is 60 ℃ for 3 hours → collection Separation with 80°C petroleum e...

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Abstract

The invention relates to a targeting antitumor and anticancer medicine. A preparation method of the medicine comprises the following steps: mixing prepared Polyrhachis Vicina Roger, prepared placenta, Radix Hedysari, cordycepin and Rhizoma Corydalis, injecting second-grade medicinal distilled water to the obtained mixture to prepare a liquid, placing the liquid in a container, adding active carbon for processing, filtering, adding to injection water and a container containing a sodium chloride solution for diluting, and uniformly stirring; adjusting the osmotic pressure of the injection water by sodium hydroxide, and filtering by a filter to obtain a filtrate according with the production requirement of a Chinese GMP standard reached large transfusion enterprise; and filling to a 250ml or 500ml glass bottle, and disinfecting under a pressure of 0.39MPa at a temperature of 116DEG C to obtain the targeting antitumor and anticancer medicine. The medicine has the advantages of safety, non-toxicity, no side effects, performance of the wide-spectrum antitumor, anticancer and anti-injection effects, containment of abundant nutritional components, participation of the immune function adjustment, and improvement of the generation level and the acceptor expression level of interleukin-2 (1L-2).

Description

technical field [0001] The invention relates to a traditional Chinese medicine preparation method and chemical agents that are routinely used without contraindications in the National Pharmacopoeia, specifically a novel targeted anti-tumor and anti-cancer agent after integration and a preparation method thereof. Background technique [0002] Cancer is still one of the most important diseases threatening human health. It takes the lives of thousands of patients every year. At present, air pollution, environmental pollution, and cancer patients are increasing year by year. As early as the 1950s and 1970s, the United States invested a lot of money and manpower, and was determined to conquer cancer at the end of the last century. However, up to now, cancer is still a worldwide problem. Countries around the world are exploring, researching and developing anti-cancer drugs. Every year, a variety of new anti-cancer drugs come out, but these drugs generally have poor efficacy and se...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/66A61P35/00A61K31/7076A61K35/64A61K35/50
Inventor 何忠琳
Owner 何忠琳
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