Controllable synthesis of lanthanum hydroxide nano-particles

Abstract

The invention relates to a method that lanthanum hydroxide nano-particles with the even sizes are synthesized by utilizing of a coprecipitation method. The method comprises that a certain proportion (weight ratio) of a dispersing agent (the dispersing agent: lanthanum chloride=0.8:1) is stirred in a magnetic mode in lanthanum chloride dilute solution with certain density to enable the dispersing agent to be fully dissolved, the temperature is risen, and hartshorn with certain density is slowly dripped to react for 1-3 hours. White precipitate is obtained through centrifugal separation after cooling, ethanol and deionized water are used for washing the white precipitate respectively, and at last lanthanum hydroxide nano-particles are obtained through drying.

Description

technical field [0001] The invention relates to the field of processing and preparation of chemical raw materials, in particular to the controllable preparation of nanometer lanthanum hydroxide. Background technique [0002] my country is the world's largest rare earth country, and rare earths have become one of the important chemical industries in my country, among which rare earth hydroxides and rare earth oxides are the most widely used varieties in the rare earth industry. Lanthanum hydroxide has received widespread attention in related fields as a catalyst, sintering aid, adsorbent, etc., but it has not been discovered in the field of medicine. At the same time, how to improve the effective characteristics of lanthanum hydroxide is also concerned by those skilled in the art At present, the most important method to improve its characteristics is to reduce its particle size and form ultrafine particles, such as lanthanum hydroxide nanoparticles, but the disadvantages of t...

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Problems solved by technology

Traditional phosphorus binders are mainly aluminum or calcium-containing phosphorus binders, but long-term use of aluminum-containing phosphorus binders can lead to aluminum retention in the body and cause serious side effects, so it is only suitable for short-term use in high blood pressure that cannot be effectively controlled by other drugs. Phosphate

However, calcium-containing phosphate binders can lead to hypercalcemia, increase the calcium-phosphorus product, and cause metastatic calcification and cardiovascular disease. Therefore, traditional phosphate binders are not ideal drugs for the treatment of hyperphosphatemia.

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