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Medicine composition for treating hepatitis, and preparation method and novel application thereof

A composition and drug technology, applied in the field of pharmaceutical composition, can solve the problems of long treatment cycle, high recurrence rate, and single effect, and achieve non-toxic and side effects, good therapeutic effect, and remarkable effect

Active Publication Date: 2014-04-16
CP PHARMA QINGDAO CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although the research and application of traditional Chinese medicine for the treatment and prevention of hepatitis are extensive, the curative effect of traditional Chinese medicine for the treatment of hepatitis is not significant, the effect is single, the pertinence is poor, the treatment cycle is long, the recurrence rate is high, and it cannot treat both the symptoms and the root causes

Method used

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  • Medicine composition for treating hepatitis, and preparation method and novel application thereof
  • Medicine composition for treating hepatitis, and preparation method and novel application thereof
  • Medicine composition for treating hepatitis, and preparation method and novel application thereof

Examples

Experimental program
Comparison scheme
Effect test

experiment example 1

[0030] Observation object and method

[0031] 1. Case selection

[0032] (1) Etiological diagnosis

[0033] Type A: Those who have any one of the following four items:

[0034] 1. Serum anti-HAVIgM positive in patients with acute hepatitis;

[0035] 2. The anti-HAVIgG titer of the double serum in the acute phase and the recovery phase increased by more than 4 times;

[0036] 3. HAV particles were detected by anti-HAV immuno-electron microscopy in feces in the early acute stage;

[0037] 4. HAAg was found in feces in the early acute stage.

[0038] Type B: Those who have any one of the following four items:

[0039] 1. Serum HbsAg positive, or HbeAg positive;

[0040] 2. Serum HbsAg positive, but anti-HbcIgM positive, or anti-HBs, or anti-HBc positive;

[0041] 3. Serum HBV-DNA or DNA polymerase positive, or HbeAg, or anti-Hbe positive;

[0042] 4. The indicators of HBV infection are not obvious or only one indicator of anti-HBc is positive, while HbcAg, HbsAg or HBV-DN...

experiment example 2

[0118] Experimental Example 2: Pharmacodynamics Experiment

Embodiment 1

[0132] Embodiment 1 capsule

[0133] Kelp extract 3kg Eucheuma extract 1kg

[0134] radish seed 50kg and inulata 30kg.

[0135] Add 15 times the amount of water to the radish seeds and Inula inulata, soak for 36 hours; decoct twice with a slow fire, the first time for 2 hours, filter the liquid medicine for later use, add 10 times the amount of water for the second time, and cook with a slow fire Decoct for 1 hour, filter the medicinal liquid for use; combine the secondary medicinal liquid and filter, collect the filtrate; concentrate the filtrate to a thick paste with a relative density of 1:1.25-1.35, bake the thick paste at a low temperature for 10 hours, and dry it Cream powder, mix dry cream powder with kelp extract and Eucheuma extract, add excipients at a weight ratio of 1:0.4 to starch, granulate, dry at 60°C, granulate and pack into capsules. Capsule specification: 0.2g / capsule, 3 times a day, 1 capsule each time.

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Abstract

The invention discloses a medicine composition for treating hepatitis and a preparation method thereof. The composition consists of kelp extract, eucheuma extract, radish seed and inula flower. The medicine composition provided by the invention is prepared by decocting with water, filtering and concentrating into clinically acceptable tablets, granules, pills or oral liquid. The medicine composition provided by the invention has the effects of comforting and protecting liver, is effective in treating acute hepatitis A, acute hepatitis A, chronic persistent hepatitis chronic active hepatitis and the like, and is significant in effect and free of toxic and side effects.

Description

technical field [0001] The invention relates to a pharmaceutical composition, in particular to a pharmaceutical composition for treating hepatitis, a preparation method and a new application thereof. Background technique [0002] Hepatitis includes acute and chronic hepatitis, chronic persistent hepatitis and chronic active hepatitis. It is a common and frequently-occurring disease, especially the liver disease caused by hepatitis B virus, which seriously endangers people's health. It is easy to develop into liver cirrhosis and even transform into liver cancer. Liver disease, especially hepatitis B, is one of the most common infectious diseases in the world. According to relevant reports, nearly 1 million people die each year due to liver disease. my country is a country with a high incidence of liver disease. At present, there are about 30 million patients with chronic hepatitis B. And 120 million hepatitis B virus carriers, accounting for more than 10% of the total populat...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/31A61P1/16A61P31/14A61P31/20
CPCY02A50/30
Inventor 王明刚任莉陈阳生
Owner CP PHARMA QINGDAO CO LTD
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