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Method for processing rehmannia and application for rehmannia in preparation for medicine

A technology for preparing medicine and rehmannia, which is applied in the field of medicine and can solve the problems of large loss of active ingredients and short shelf life of fresh rehmannia

Active Publication Date: 2013-04-24
JINAN SUNNYPHARMACY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] The purpose of the present invention is to solve the short shelf life of fresh rehmannia glutinosa and the large loss of active ingredients in the processing process in the prior art, and to provide a processing method that is convenient for storage and transportation without losing active ingredients

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0056] Take fresh rehmannia glutinosa, wash and remove impurities, and cut into 5cm-long rehmannia section; put the rehmannia section on a plate, with a loading capacity of about 4Kg / ㎡; control the freezing temperature at -28°C; when the controlled temperature is reached, immediately turn on the vacuum pump to evacuate to The pressure of the drying chamber is below 50Pa, and then start the heating switch to promote the sublimation; the temperature of the sublimation should be controlled below 40°C; the temperature of the analysis stage should be controlled below 45°C. Prepare freeze-dried rehmannia glutinosa.

Embodiment 2

[0058] Take fresh rehmannia glutinosa, wash and remove impurities, and cut into 3cm-long rehmannia section; put the rehmannia section on a plate, with a loading capacity of 8Kg / ㎡; control the freezing temperature between -32°C; when the controlled temperature is reached, immediately turn on the vacuum pump to draw a vacuum When the pressure in the drying chamber is below 50Pa, then start the heating switch to promote sublimation; the sublimation temperature should be controlled below 40°C; the temperature in the analysis stage should be controlled below 45°C. Prepare freeze-dried rehmannia glutinosa.

[0059] Take freeze-dried Rehmannia glutinosa, crush it, pass through a 80-mesh sieve, and form pills with water. It is used for cancerous fever, 10g per serving, given with water, 3 times a day, and cured within 7 days.

Embodiment 3

[0061] Adopt ZG-100㎡ type vacuum freeze dryer. Select fresh rehmannia glutinosa, wash and remove impurities, cut into 2cm long rehmanniae segments, put them on a plate, the weight of the plate is about 7kg / ㎡, gradually cool down for 2 hours and then pre-freeze at -28°C; then vacuumize the system to an absolute pressure of 40Pa , start heating to 35°C, sublimation and drying for 15 hours; then keep the material temperature at 35°C, and when the material temperature is close to the heating temperature, the drying ends, and freeze-dried rehmannia glutinosa is obtained.

[0062] Take freeze-dried Rehmannia glutinosa and crush it into coarse powder, add 4 times the amount of water, stir and extract at 20°C for 4 hours, twice in total, combine the extracts, filter, centrifuge, put the centrifugate into a freeze-drying box, and freeze-dry. Freeze-dried Rehmannia glutinosa extract was obtained.

[0063] Take 1 kg of Atractylodes macrocephala, 0.5 kg of ginseng, extract with water t...

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PUM

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Abstract

The invention relates to a method for processing rehmannia, which is characterized in that fresh rehmannia is freeze-dried; and with the adoption of the method for processing rehmannia disclosed by the invention, more active ingredients of rehmannia can be reserved. The medicine is prepared from fresh rehmannia or freeze-dried rehmannia and has remarkable treating effect on cancerous fever, habitual constipation, alopecia and Alzheimer disease.

Description

technical field [0001] The invention relates to medicines, in particular to a method for processing rehmannia glutinosa and its application in preparing medicines, belonging to the technical field of medicines. Background technique [0002] Rehmannia glutinosa is the fresh or dried root tuber of Rehmannia glutinosa Li-bosch. Excavated in autumn, remove reed heads, fibrous roots and silt, used fresh, commonly known as "fresh rehmannia". It is slowly baked until it is 80% dry, and it is commonly called "shengdihuang". Stew rehmannia glutinosa with wine (Appendix II D of the 2010 edition of the Chinese Pharmacopoeia) until the wine is exhausted, take it out, and dry it in the sun until the mucus on the outer skin is slightly dry; or steam it until black Moisten it, take it out, and when it is about 80% dry, cut it into thick slices or pieces, and dry it to get "Rehmannia glutinosa". The three kinds of rehmannia have different medicinal effects. Fresh rehmannia has the effect...

Claims

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Application Information

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IPC IPC(8): A61K36/804F26B5/06A61P35/00A61P29/00A61P1/10A61P15/14A61P25/28A61P7/02A61P9/10
Inventor 张为胜许翠萍郭美莹李诗标许竹梅
Owner JINAN SUNNYPHARMACY
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