Chinese medicinal preparation for treating and preventing hypertension and preparation method thereof
A traditional Chinese medicine preparation and high blood pressure technology, which is applied in the field of medicine, can solve the problems of short duration of action, elevated blood potassium, azotemia, etc., and achieve the effects of low drug toxicity, improvement of dizziness symptoms, and reduction of arterial diastolic pressure Effect
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Embodiment 1
[0070] Take 600 grams of Salvia miltiorrhiza, 300 grams of Wang Buliuxing, and 300 grams of angelica, add water to decoct twice, the first time 10 times the amount of water for 2 hours, the second time 8 times the amount of water for 1.5 hours, filter, combine the filtrate, Load the sample on AB-8 macroporous resin, elute with 1 times the column volume of water, discard the eluent, and elute with 4 times the column volume of 75% ethanol, recover the ethanol from the eluate, concentrate to the relative density at 50°C For 1.2, get Danshen, Wang Buliuxing and Angelica extract;
[0071] Get 240 grams of Uncaria, add 0.7 times the amount of 10% sodium bicarbonate and mix well, let it stand for 14 hours, and extract it with ethanol with a concentration of 75% (V / V), recycle the ethanol from the extract, and concentrate to a relative density of 50 ° C. For 1.15, get Uncaria extract;
[0072] Combine salvia miltiorrhiza, wangbuliuxing, angelica extract and Uncaria extract, add 32g o...
Embodiment 2
[0074] Take 900 grams of Salvia miltiorrhiza, 300 grams of Wang Buliuxing, 300 grams of Angelica sinensis, and 300 grams of Uncaria uncaria, and use 70% ethanol to reflux extract twice, the first time is 8 times the amount, 3 hours, the second time is 6 times the amount, After 2 hours, filter, combine the filtrates, recover ethanol until there is no alcohol smell, and obtain an alcohol extract; load the sample on AB-8 macroporous resin, elute with 1.5 times the column volume of water, and discard the eluent; Volume and concentration of 70% ethanol for elution, ethanol is recovered from the eluent, and the relative density is 1.30 when concentrated to 50°C, to obtain Danshen, Wangbuliuxing, Angelica and Uncaria extracts;
[0075] Add 120 g of starch, mix well, dry at 70°C until the water content is lower than 5%, pass through a No. 7 sieve, and pack into capsules to obtain 2000 capsules.
Embodiment 3
[0077] Take 300 grams of Salvia miltiorrhiza, 200 grams of Wang Buliuxing, 300 grams of Angelica sinensis, 200 grams of Uncaria uncariae, add 75% ethanol to reflux and extract twice, the first time is 8 times the amount, 3 hours, the second time is 6 times the amount, After 2 hours, filter, combine the filtrates, recover ethanol until there is no alcohol smell, and continue to concentrate until the relative density is 1.31 at 50°C to obtain the extracts of Danshen, Wangbuliuxing, Angelica and Uncaria;
[0078] Add 90 g of dextrin, mix well, granulate with a 24-mesh sieve, and dry at 70°C until the water content is lower than 5%, to obtain 120 g of granules.
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