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Traditional Chinese medicine composition for treating nephritis as well as preparation method and application of composition

A composition and technology of traditional Chinese medicine, applied in the field of traditional Chinese medicine composition for treating nephritis and its preparation, can solve the problems of large side effects, etc., and achieve the effect of strict compatibility, no toxic and side effects, and definite curative effect

Inactive Publication Date: 2013-02-27
QINGDAO MUNICIPAL HOSPITAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, Western medicine mostly uses infusion plus antibacterial and anti-inflammatory drugs (such as penicillin) for treatment, and the side effects are relatively large. Traditional Chinese medicine treatment believes that the disease is mostly empirical.

Method used

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  • Traditional Chinese medicine composition for treating nephritis as well as preparation method and application of composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] Example 1: Take 20g astragalus, 25g yam, 15g smilax, 25g Liuyuexue, 10g mistletoe, 20g rehmannia, 15g rhodiola, 25g heterophylla, 30g diffusa, 25g lychee, 15g Eucommia, wolfberry Combine 25g of seeds and 15g of corn silk as medicinal materials, add water to decoct twice, add water for the first time to 8 times the weight of the medicinal materials, decoct for 1 hour, add water for the second time to 6 times the weight of the medicinal materials, decoct for 1 hour, and combine the decoction , 0.07MPa, concentrated under reduced pressure at 60-70°C to 65°C, the relative density is 1.10, add 95% (v / v) ethanol to make the alcohol content reach 85% (v / v), stir, and stand for 24 hours, The filtrate is decompressed to recover ethanol and concentrated, and the filtrate is concentrated under reduced pressure at 0.07MPa and 65°C to a relative density of 1.30 at 65°C, and spray-dried (conditions are that the inlet air temperature is 120°C, the outlet air temperature is 100°C, and t...

Embodiment 2

[0021] Example 2: Take 25g astragalus, 20g yam, 20g smilax, 20g Junexue, 15g mistletoe, 15g rehmannia, 20g rhodiola, 20g heterophylla, 35g diffusa, 20g lychee, 20g Eucommia, wolfberry Combine 20g of seeds and 20g of corn silk, add water to decoct twice, add water for 10 times the weight of the medicinal materials for the first time, decoct for 1.5h, add water for the second time 8 times the weight of the medicinal materials, decoct for 1.5h, and combine Decoction, 0.07MPa, concentrated under reduced pressure at 60-70°C to a relative density of 1.15 at 65°C, add 95% (v / v) ethanol to make the alcohol content reach 75% (v / v), stir, and stand for 24 Hours, the filtrate was decompressed to recover ethanol and concentrated, and the filtrate was concentrated under reduced pressure at 0.07MPa and 65°C to a relative density of 1.25 when it reached 65°C, and was spray-dried (conditions were that the inlet air temperature was 100°C, and the outlet air temperature was 80°C , the material ...

Embodiment 3

[0022] Example 3: Take 30g of astragalus, 15g of yam, 25g of Smilax smilax, 15g of Liuyuexue, 20g of mistletoe, 10g of rehmannia glutinosa, 25g of rhodiola rosea, 15g of heterophylla, 40g of Hedyotis diffusa, 15g of litchi grass, 25g of Eucommia ulmoides, and wolfberry Combine 15g of seeds and 25g of corn silk, add water to decoct twice, add water to 12 times the weight of the medicinal materials for the first time, decoct for 2 hours, add water for the second time to 10 times the weight of the medicinal materials, decoct for 2 hours, and combine the decoction , 0.07MPa, concentrated under reduced pressure at 60-70°C to 65°C, the relative density is 1.15, add 95% (v / v) ethanol to make the alcohol content reach 75% (v / v), stir, and stand for 24 hours, The filtrate is decompressed to recover ethanol and concentrated, and the filtrate is concentrated under reduced pressure at 0.07MPa and 65°C to a relative density of 1.25 when it reaches 65°C, and is spray-dried (conditions are th...

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Abstract

The invention provides a traditional Chinese medicine composition for treating nephritis. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 20-30 parts of astragalus root, 15-25 parts of yam, 15-25 parts of rhizoma smilacis glabrae, 15-25 parts of serissa serissoide, 10-20 parts of mistletoe, 10-20 parts of rehmannia, 15-25 parts of rhodiola rosea, 15-25 parts of radix pseudostellariae, 30-40 parts of oldenlandia diffusa, 15-25 parts of common sage herb, 15-25 parts of eucommia, 15-25 parts of medlar and 15-25 parts of corn stigma. The traditional Chinese medicine composition has the functions of inducing mild diaphoresis, clearing heat and removing pattogenic heat from the blood and toxic material from the body, so that the composition can be used for treating nephritis. The invention further discloses a preparation method and an application.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine, in particular to a traditional Chinese medicine composition for treating nephritis, a preparation method and application thereof. Background technique [0002] Nephritis is a non-suppurative inflammatory lesion of both kidneys. Kidney edema, high blood pressure, proteinuria and other phenomena due to damage to the renal corpuscles are the most common types of kidney disease. The pathological change of acute glomerulonephritis is that the volume of the kidney can increase compared with normal, and the lesion mainly involves the glomerulus. The pathological type is intracapillary proliferative glomerulonephritis. Under the light microscope, it usually shows diffuse glomerular lesions, mainly manifested by proliferation of endothelial cells and mesangial cells, and may be accompanied by infiltration of neutrophils and monocytes in the acute phase. When the lesion is severe, t...

Claims

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Application Information

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IPC IPC(8): A61K36/90A61P13/12
Inventor 不公告发明人
Owner QINGDAO MUNICIPAL HOSPITAL
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