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Application of composition of Chinese yarn polysaccharide and Chinese yarn protein

A technology of yam protein and yam polysaccharide, which is applied in the direction of drug combination, peptide/protein composition, medical preparations containing active ingredients, etc.

Inactive Publication Date: 2013-02-13
新疆乐美健生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The natural composition of yam polysaccharide and yam protein is the active ingredient extracted from the rhizome of the yam plant of the genus Dioscorea in the family Dioscorea. It is pointed out in (Patent No. ZL201010171536.1) that it has the effect of treating sleep apnea syndrome. The present invention is based on this Further studies have shown that: yam polysaccharides and yam protein compositions have good effects on the main components of metabolic syndrome, obesity, insulin resistance, type 2 diabetes, hyperlipidemia, hypertension, fatty liver and the resulting heart and kidney damage. Therapeutic and protective effects of yam polysaccharide and yam protein composition are derived from natural plants, the drug source is sufficient, and the extraction and preparation method is simple and easy. It can be made into various dosage forms such as capsules, tablets, granules, and oral liquids. Effectively treat heart and kidney damage caused by obesity, insulin resistance, type 2 diabetes, hyperlipidemia, high blood pressure, fatty liver and the above-mentioned component diseases of metabolic syndrome, but so far, no see related reports

Method used

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  • Application of composition of Chinese yarn polysaccharide and Chinese yarn protein
  • Application of composition of Chinese yarn polysaccharide and Chinese yarn protein
  • Application of composition of Chinese yarn polysaccharide and Chinese yarn protein

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0015] a. Use the dried rhizome of the native yam as a raw material to remove plant impurities, weigh 10 kilograms and crush it, heat it with water twice the weight of the yam, at a temperature of 50°C, reflux and extract twice for 2 hours, filter and combine the extracts , The extract is filtered and concentrated to 50%;

[0016] b. Add 95% ethanol to the concentrate to make the alcohol content of the concentrate reach 30%, and remove the precipitate after precipitation occurs;

[0017] c. Continue to add 95% ethanol to the concentrated solution to make the alcohol content reach 90%. After the precipitate appears, let it stand for 3 hours. After the precipitate is fully precipitated, the supernatant is removed to collect the precipitate, and then dried and crushed , You can obtain a composition with a yellow-brown powdered yam polysaccharide content of 40-50% and a yam protein content of 30-40%.

Embodiment 2

[0019] a. Use the dried rhizome of the native yam as a raw material to remove plant impurities, weigh 10 kilograms and crush it, heat it with water 5 times the weight of the yam, at a temperature of 100 ℃, reflux and extract 3 times for 3 hours, filter and combine the extracts , Filter and concentrate to 50%;

[0020] b. Add 95% ethanol to the concentrate to make the alcohol content of the concentrate reach 30%, and remove the precipitate after precipitation occurs;

[0021] c. Continue to add 95% ethanol to the concentrated solution to make the alcohol content reach 90%. After the precipitate appears, let it stand for 6 hours. After the precipitate is fully precipitated, the supernatant is removed to collect the precipitate, and then dried and crushed , You can obtain a composition with a yellow-brown powdered yam polysaccharide content of 40-50% and a yam protein content of 30-40%.

Embodiment 3

[0023] a. Using the dried rhizome of the native yam as a raw material, removing plant impurities, weighing 10 kilograms, smashing, heating with water 3.5 times the weight of the yam, at a temperature of 80°C, refluxing and extracting 3 times for 2.5 hours, filtering, and combining the extracts. Filter and concentrate to 50%;

[0024] b. Add 95% ethanol to the concentrate to make the alcohol content of the concentrate reach 30%, and remove the precipitate after precipitation occurs;

[0025] c. Continue to add 95% ethanol to the concentrated solution to make the alcohol content reach 90%. After the precipitate appears, let it stand for 4.5 hours. After the precipitate is fully precipitated, the supernatant is removed to collect the precipitate, and then dried and crushed , You can obtain a composition with a yellow-brown powdered yam polysaccharide content of 40-50% and a yam protein content of 30-40%.

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Abstract

The invention relates to an application of a composition of Chinese yarn polysaccharide and Chinese yarn protein. Summarization and analysis of a large amount of clinic observation and an animal test prove that the composition of Chinese yarn polysaccharide and Chinese yarn protein can effectively treat metabolic syndromes characterized by obesity, insulin resistance, hypertension, hyperlipidmia and fatty liver and heart and kidney damages caused by the metabolic syndromes.

Description

Technical field [0001] The invention relates to the use of a composition of yam polysaccharide and yam protein, specifically, it relates to the preparation and treatment of a natural composition of yam polysaccharide and yam protein in the treatment of obesity, insulin resistance, type 2 diabetes, hypertension, hyperlipidemia, and fat. Metabolic syndrome characterized by liver and its use in drugs that cause heart and kidney damage. Background technique [0002] Metabolic syndrome is composed of obesity, especially abdominal obesity, lipid metabolism disorders (increased triglycerides, low-density lipoproteins) glucose metabolism disorders (impaired glucose tolerance, type 2 diabetes), hypertension, and other diseases Disease groups, as early as the 1950s, some international medical scientists observed that obesity, especially abdominal obesity, is often accompanied by lipid metabolism disorders, glucose metabolism disorders and hypertension, and the above diseases often occur in...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K38/00A61K36/8945A61P3/04A61P3/10A61P9/12A61P3/06A61P1/16A61P9/00A61P13/12A61K31/715
CPCA61K38/00A61K36/8945A61P1/16A61P3/04A61P3/06A61P3/10A61P9/00A61P9/12A61P13/12
Inventor 多力坤·马木特
Owner 新疆乐美健生物科技有限公司
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