Liquid oral preparation for treating malignant tumor and preparation method

Abstract

The invention relates to an oral preparation taking natural plants as the main medicinal components and supplemented with special medicinal auxiliary materials and a preparation method of the oral preparation. The liquid oral preparation for treating the malignant tumor, provided by the invention, is prepared by the following raw and auxiliary materials according to the weight ratio: 20 parts of ferula asafetida, 30 parts of aspongopus, 20 parts of clove, 20 parts of radix aucklandiae, 40 parts of rheum officinale, 40 parts of radix curcumae longae, 26 parts of fructus chebulae, 4 parts of cordyceps sinensis, 1.0 to 2.0 parts of polysorbate 80, 5 to 25 parts of povidone (PVP) K15 or K60 and 1.0 to 2.5 parts of sodium cyclamate. The innovation of the invention is as follows: the oral liquid preparation is applied to the modern novel auxiliary materials for the first time, so that the treatment effect of the medicines is improved, the solubility of the aqueous solution of slightly-soluble medicines is further improved, further, the medicines are in a uniform true solution state or a highly-dispersed state, the aggregation of the molecular crystals is prevented, and the stability of the medicines is improved; and furthermore, the active substance (curcumin) in the medicines is kept to be stable and is prevented from the oxidation and hydrolysis, and the antioxidant and anti-tumour functions of the medicines are enhanced.

Description

technical field [0001] The invention relates to an oral preparation made of natural plants as main medicinal ingredients and supplemented with specific medicinal auxiliary materials, and a preparation method thereof. Background technique [0002] Tumor is a malignant disease that seriously endangers human health. In my country, more than 1 million patients die from tumor diseases every year, which has become the primary factor of urban population death in my country. ", "Eleventh Five-Year Plan" will be the research and development of anti-tumor drugs as a major national science and technology projects to the project. In recent years, the scale of the domestic anti-tumor drug market has shown an obvious upward trend. By the end of 2010, the global anti-tumor drug market will reach 60 billion yuan, with an annual growth rate of more than 10%, and the growth rate in my country is 17%. At present, there are more than 200 anti-tumor drugs that have been approved for marketing in...

AI Technical Summary

Problems solved by technology

The medicine described in this invention is a conventional preparation, such as tablets, capsules, etc., and is mainly applicable to the treatment of digestive tract malignant tumors (esophageal cancer, liver cancer, gastric cancer, pancreatic cancer, colorectal cancer), breast tumors, cervical cancer, and lung cancer. Due to the limitations of traditional dosage forms, it takes a long time for the dissolution and absorption of the drug, and the blood drug concentration fluctuates greatly, so that the curative effect of the product cannot be fully exerted, and it cannot achieve a rapid treatment effect for patients who need rapid relief of symptoms

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