External use ointment for promoting wound healing without scar pigment and preparation method of external use ointment
A technology of wound healing and topical ointment, which is applied in the direction of medical preparations containing active ingredients, ointment delivery, drug combination, etc., can solve problems that have not been seen yet, achieve no scar and pigmentation, protect the wound surface, and smooth the skin of the wound surface Effect
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Embodiment 1
[0042] Embodiment 1: the preparation of hydrophilic ointment base cream for external use
[0043] 1) Take commercially available raw materials: Centella asiatica extract 20g, aloe extract 20g, salvia miltiorrhiza extract 12g, knotweed extract 8g, dandelion extract 7g and Burnet extract 6g, mix well;
[0044] 2) Soak the mixture in ethanol with a concentration of 75% by mass, reflux and refine it at 70-80°C for 3 times, combine the filtrate each time, and perform conventional decolorization treatment;
[0045] 3) Concentrate the decolorizing solution into an extract, lower the temperature to 40-50°C, add 10g of pearl powder, 6g of bletilla striata powder and 2g of tea polyphenol powder, mix and stir to room temperature, then add 0.1g of peppermint oil, 0.3 of chlorhexidine g, continue to stir evenly to obtain a mother paste containing active ingredients;
[0046] 4) The hydrophilic ointment base contains 25% white petrolatum, 25% stearyl alcohol, 12% propylene glycol and 1.5% ...
Embodiment 2
[0047] Embodiment 2: the preparation of water-in-oil cream matrix topical ointment
[0048] 1) Take commercially available raw materials: 25g of centella asiatica extract, 22g of aloe extract, 8g of salvia miltiorrhiza extract, 10g of knotweed extract, 6g of dandelion extract and 8g of Burnet extract, and mix well;
[0049] 2) Soak the mixture in ethanol with a concentration of 95% by mass, reflux and refine it twice at 70-80°C, combine the filtrates each time, and perform conventional decolorization treatment;
[0050] 3) Concentrate the decolorization solution into an extract, lower the temperature to 40-50°C, add 15g of pearl hydrolyzate, 8g of bletilla striata powder and 1g of tea polyphenol powder, mix and stir to room temperature, then add 0.08g of peppermint oil and chlorhexidine 0.5g, continue to stir evenly to obtain a mother paste containing active ingredients;
[0051] 4) Water-in-oil cream base (W / O cream base) contains 10% glyceryl monostearate, 10% solid paraffi...
Embodiment 3
[0052] Embodiment 3: the preparation of emulsion base cream for external use
[0053] 1) Take commercially available raw materials: 15g of centella asiatica extract, 18g of aloe extract, 15g of salvia miltiorrhiza extract, 5g of knotweed extract, 5g of dandelion extract and 10g of Burnet extract, and mix well;
[0054] 2) Soak the mixture in ethanol with a concentration of 80% by mass, reflux at 70-80°C for three times, combine the filtrates each time, and perform conventional decolorization treatment;
[0055] 3) Concentrate the decolorizing solution into an extract, lower the temperature to 40-50°C, add 18g of pearl powder, 5g of bletilla striata powder and 1.5g of tea polyphenol powder, mix and stir to room temperature, then add 0.05g of peppermint oil and chlorhexidine 0.2g, continue to stir evenly to obtain a mother paste containing active ingredients;
[0056] 4) The emulsion base contains 1.5% stearic acid, 6% white petrolatum, 1.5% cetyl alcohol, 0.3% olive oil, 0.5% ...
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