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Pharmaceutical composition for treating apoplexy hemiplegia and preparation method of pharmaceutical composition

A technology of composition and medicine, which is applied in the field of pharmaceutical composition and its preparation for the treatment of stroke hemiplegia, can solve the problems of high cost, difficulty in reducing cost, and increasing the economic burden of patients, and achieve easy access, inhibition of thrombus formation, and good treatment The effect of action

Active Publication Date: 2012-11-14
重庆希尔安药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In the above cases, there are many medicinal flavors and the cost is too high, and it will be difficult to reduce the cost in application, especially in mass production, which will increase the economic burden of patients

Method used

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  • Pharmaceutical composition for treating apoplexy hemiplegia and preparation method of pharmaceutical composition
  • Pharmaceutical composition for treating apoplexy hemiplegia and preparation method of pharmaceutical composition
  • Pharmaceutical composition for treating apoplexy hemiplegia and preparation method of pharmaceutical composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0069] The composition of the present invention is prepared from the following raw materials: Astragalus 800g, Erigeron breviscapine 800g, hawthorn 200g, Achyranthes bidentata 500g, Atractylodes macrocephala 200g, safflower 200g, red peony root 200g, chuanxiong 500g, angelica 200g, osmanthus twig 200g, leech 200g , gastrodia elata 100g, earthworm 50g;

[0070] The preparation method of composition of the present invention is:

[0071] a) Crush breviscapine, leeches, Gastrodia elata, and earthworm together into coarse powder, soak them in 60% ethanol which is 10 times the total amount, and then percolate for 30 minutes, collect the percolation liquid, and recover the ethanol until it is free of alcohol taste, and concentrated to 60 ° C to measure the extract with a relative density of 1.15;

[0072] b) The medicinal dregs after percolation in step a) are decocted twice with 8 times the amount of water for the remaining 9 raw materials, the first time is 2 hours, the second tim...

Embodiment 2

[0075] The composition of the present invention is prepared from the following raw materials: Astragalus 1800g, Erigeron breviscapine 1800g, hawthorn 800g, Achyranthes bidentata 1500g, Atractylodes macrocephala 800g, safflower 800g, red peony 800g, chuanxiong 1500g, angelica 500g, cassia twig 500g, leech 500g , gastrodia elata 300g, earthworm 200g;

[0076] The preparation method of composition of the present invention is:

[0077] a) Crush breviscapine, leeches, Gastrodia elata, and earthworm together into coarse powder, soak them in 60% ethanol which is 10 times the total amount, and then percolate for 30 minutes, collect the percolation liquid, and recover the ethanol until it is free of alcohol taste, and concentrated to 60 ° C to measure the extract with a relative density of 1.10;

[0078] b) The medicinal dregs after percolation in step a) are decocted twice with 7 times the amount of water used for the remaining 9 raw materials, the first time is 2 hours, the second t...

Embodiment 3

[0081] The composition of the present invention is prepared from the following raw materials: astragalus 1000g, breviscapine 1000g, hawthorn 300g, achyranthes bidentata 600g, Atractylodes macrocephala 300g, safflower 300g, red peony 300g, chuanxiong 600g, angelica 300g, cassia twig 300g, leech 300g , Tianma 150g, Dilong 100g;

[0082] The preparation method of the composition of the present invention is: same as the preparation process of Example 1

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Abstract

The invention relates to a pharmaceutical composition for treating apoplexy hemiplegia and a preparation method of the pharmaceutical composition. The pharmaceutical composition for treating apoplexy hemiplegia selectively comprises astragalus, erigeron breviscapus, hawthorn, bidentate achyranthes, bighead atractylodes rhizome, safflower, red peony roots, Szechuan lovage rhizome, Chinese angelica, cassia twig, leech, tall gastrodia tuber and earthworm. Required formulations prepared by a conventional preparation method by the aid of the modern preparation technology have effects of supplementing qi, activating blood circulation, dispersing blood stasis and dredging collaterals, and are used for treating apoplexy hemiplegia symptoms of hemiplegia, facial paralysis, limbs numbness and the like caused by apoplexy. The pharmaceutical composition for treating apoplexy hemiplegia is applied to clinical treatment and is effective in treatment.

Description

【Technical field】 [0001] The invention belongs to the field of traditional Chinese medicine, in particular to a pharmaceutical composition for treating apoplexy and hemiplegia and a preparation method thereof. 【Background technique】 [0002] "Stroke" is generally called "stroke", which is a common disease worldwide. It is a focal blood circulation disorder caused by cerebral arteries or carotid artery lesions that supply blood to the brain, resulting in acute or subacute brain damage. Symptoms are hemiplegic aphasia and coma. [0003] The annual incidence rate of stroke is 140 / 100,000 to 200 / 100,000 population on average worldwide, and it is higher in Orientals than in Westerners. The mortality rate of stroke in my country is between 80 / 100,000 and 140 / 100,000. The prevalence of stroke among urban residents in my country is relatively high, reaching an average of 700 / 100,000 population. The prevalence rate in rural areas is lower than that in cities, with an average of 30...

Claims

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Application Information

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IPC IPC(8): A61K36/8988A61P9/10A61K35/62A61K35/64
Inventor 吕姗珊周年华唐桂英谯志文高燕妮陈晓雪高武翔陈成
Owner 重庆希尔安药业有限公司
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