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Traditional Chinese medicine composition for treating acute upper gastrointestinal hemorrhage, as well as preparation method and application thereof

A technology of gastrointestinal bleeding and composition, applied in the field of traditional Chinese medicine, can solve the problems of poor hemostatic effect of western medicine and the like

Inactive Publication Date: 2013-12-18
如皋市江北添加剂有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] The technical problem to be solved by the present invention is that, based on the above-mentioned TCM treatment theory for the treatment of acute upper gastrointestinal bleeding, it is proposed to clear away heat and reduce fire, cool blood to stop bleeding, invigorate the spleen and replenish qi as the treatment principles, and provide a method for treating acute upper gastrointestinal bleeding. The traditional Chinese medicine composition for bleeding, the use of this traditional Chinese medicine composition can overcome the poor hemostatic effect of western medicine and the defects of easy to produce toxic and side effects, and has the advantages of good curative effect and quick effect

Method used

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Examples

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Effect test

preparation example Construction

[0065] The present invention provides the preparation method of above-mentioned Chinese medicine composition, it comprises:

[0066] In the first step, put the palm, sea octopus, Panax notoginseng, agrimony, rhubarb, ginkgo biloba, big thistle, big-leaf purple pearl, salvia miltiorrhiza, motherwort and three-edge into a frying pan and fry them into charcoal, and then crush them separately with a grinder into fine powder, sieved into 100-200-mesh powder, and then mixed;

[0067] In the second step, the mixed powder is dissolved in ethanol with an alcohol concentration of 70% to 80%, soaked for 24 hours to 36 hours, and slowly percolated at a rate of 2 to 4ml per minute by the percolation method, and the percolation powder is collected. The mass of the added ethanol is 5-8 times the mass of the mixed powder, the temperature is 55°C, the vacuum is 267Pa, and the concentration is reduced to about 1 / 10 of the original volume, and the supernatant is too large Pore ​​resin column ad...

Embodiment 1

[0075] Example 1 Injection 1 prepared by the present invention

[0076] Put 26g of palm, 22g of sea octopus, 80g of Panax notoginseng, 18g of agrimony, 35g of rhubarb, 38g of ginkgo biloba, 17g of thistle, 15g of purple pearl, 25g of salvia miltiorrhiza, 25g of motherwort and 15g of trigonium into a frying pan and stir-fry into charcoal. Use a pulverizer to crush it into fine powder, sieve it into 100-mesh powder, and then mix; dissolve the mixed powder in 1900g of ethanol with an alcohol concentration of 80%, soak for 24 hours, and use the percolation method at a rate of 2ml per minute. Slowly percolate at a high speed, collect the percolate, concentrate under reduced pressure to about 1 / 10 of the original volume at a temperature of 55°C and a vacuum of 267Pa, centrifuge at 15,000rpm, and pass the supernatant through a D101 macroporous resin column for adsorption , first eluted with 1000g of water and discarded, then eluted with gradient ethanol, first eluted with 1300g alcoh...

Embodiment 2

[0081] Embodiment 2 Injection 2 prepared by the present invention

[0082]Put 30g of palm, 24g of sea octopus, 85g of Panax notoginseng, 19g of agrimony, 37g of rhubarb, 40g of ginkgo biloba, 18g of thistle, 16g of big leaf purple pearl, 23g of salvia miltiorrhiza, 27g of motherwort and 14g of three edges into a frying pan and stir-fry into charcoal. Use a pulverizer to crush it into fine powder, sieve it into 100-mesh powder, and then mix; dissolve the mixed powder in 1900g of ethanol with an alcohol concentration of 80%, soak for 24 hours, and use the percolation method at a rate of 2ml per minute. Slowly percolate at a high speed, collect the percolate, concentrate under reduced pressure to about 1 / 10 of the original volume at a temperature of 55°C and a vacuum of 267Pa, centrifuge at 15,000rpm, and pass the supernatant through a D101 macroporous resin column for adsorption , first eluted with 1000g of water and discarded, then eluted with gradient ethanol, first eluted wit...

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Abstract

The invention provides a traditional Chinese medicine composition for treating acute upper gastrointestinal hemorrhage, which comprises fortune windmillpalm petiole, cuttlebone, pseudo-ginseng, hairyvein agrimonia herb and bud, rheum officinale, folium ginkgo, Japanese thistle herb or root, bigleaf beautyberry leaf, radix salviae miltiorrhizae, motherwort, common burreed rhizome, radix scutellariae, folium isatidis, tree peony bark, sinkiang arnebia root, astragalus, Chinese yam, acanthopanax root and fructus lycii. The traditional Chinese medicine composition overcomes the defects that Western medicines are poor in hemostasis effect and easily generate toxic and side effects, and has the advantages of being good in treatment effect and rapid in effect.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine, in particular to a traditional Chinese medicine composition for treating acute upper gastrointestinal bleeding. Background technique [0002] Acute upper gastrointestinal bleeding refers to the bleeding caused by the gastrointestinal tract above the ligament of Treitz, including the esophagus, stomach, duodenum, or pancreaticobiliary lesions; bleeding from jejunal lesions after gastrojejunostomy also falls into this category and is a common clinical phenomenon in internal medicine. Emergencies are mostly caused by peptic ulcer, rupture of esophageal and gastric varices, acute gastric mucosal lesions and gastric cancer; those caused by gastroesophageal reflux disease and esophageal and cardiac mucosal tear syndrome are also uncommon. This disease occurs in winter and spring, and there are more men than women. If the treatment is not timely or appropriate, the fatality rate is ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/902A61K36/9066A61P1/00A61P7/04A61K35/56A61K35/618
Inventor 彭桂花王咏梅于海涛翟萍
Owner 如皋市江北添加剂有限公司
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