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Traditional Chinese medicine composition for treating uterine fibroid

A technology for uterine fibroids and compositions, which is applied in drug combinations, antineoplastic drugs, and pharmaceutical formulations, and can solve problems such as large side effects of hormone therapy, canceration of fibroids, and easy complications

Inactive Publication Date: 2012-09-19
GUANGZHOU JIAYUAN PHARMA TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, uterine fibroids are easy to recur, proliferate and produce benign degeneration. With the improvement of living standards, women's menopause is also gradually delayed, which leaves many patients with recurrent attacks, prone to complications, and Hidden dangers such as fibroid canceration
[0004] At present, in terms of various treatment methods for this disease, surgical treatment is the most helpless choice, hormone therapy has too many side effects, and conservative treatment faces the risk of difficult control of the disease
At present, no matter Chinese or Western medicine, there is no drug that can completely and effectively inhibit the growth of uterine fibroids, shrink or eliminate tumors, improve clinical symptoms, and prevent the recurrence and malignant transformation of fibroids

Method used

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  • Traditional Chinese medicine composition for treating uterine fibroid
  • Traditional Chinese medicine composition for treating uterine fibroid
  • Traditional Chinese medicine composition for treating uterine fibroid

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0016] Embodiment 1 Chinese medicine composition of the present invention is to the drug efficacy evaluation of hysteromyoma rats

[0017] 1. Experimental animal model and group administration

[0018] 50 clean non-pregnant female SD rats, body weight 190-210g, were randomly divided into 5 groups, 10 in each group; i.e. blank group, model group, high, medium and low dose groups of decoction of the present invention. Except for the blank group, the above-mentioned animals were intramuscularly injected with 0.1 ml (0.04 mg) of diethylstilbestrol (0.04 mg) and 0.1 ml (1.0 mg) of progesterone, each once a day for 30 days. An animal model of rat uterine fibroids was established.

[0019] The water decoction of the composition of the present invention takes by weight 18 parts of pagoda japonica, 12 parts of mallow seed, 8 parts of sumac, 4 parts of water safflower seed, 12 parts of Herba chinensis, 18 parts of sarcocarpus, 18 parts of golden buckwheat 18 parts, prepared by convent...

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Abstract

The invention discloses a traditional Chinese medicine composition for treating uterine fibroid and belongs to the field of traditional Chinese medicine. Chinese medicinal crops of sophora flower buds, cluster mallow fruit,lignum sappan, fruits of polygonum orientale, potentilla discolor, herb of glabrous sarcandra and wild buckwheat are composited to form active pharmaceutical ingredients and the are added with common excipients so as to form an oral preparation. The traditional Chinese medicine composition is capable of improving clinical symptoms of and has good therapeutic effect for female patients with uterine fibroid.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition for treating uterine fibroids, belonging to the field of traditional Chinese medicines. technical background [0002] Uterine fibroids, also known as uterine leiomyomas, are the most common benign tumors of the female genitalia. Uterine fibroids are called the first tumor in gynecology, which is a common and frequently-occurring disease in women. The incidence rate of uterine fibroids in women of childbearing age is 30%, and the incidence rate of women over 35 years old is as high as 40%. It rarely occurs before the age of 20 and after the age of 60, and more than 90% of them are concentrated between the ages of 30 and 50. Most of the disease is asymptomatic, and a few manifest as vaginal bleeding, palpable mass in the abdomen, and compression symptoms; if pedicle torsion or other conditions occur, it can cause pain, which is common in multiple uterine fibroids. The exact cause of t...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/73A61P35/00A61P15/00
Inventor 王素侠樊婷婷
Owner GUANGZHOU JIAYUAN PHARMA TECH
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