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Chinese medicinal composition for treating diabetes mellitus

A composition and diabetes technology, applied in the field of medicine, can solve problems such as large differences in curative effect

Active Publication Date: 2012-08-15
王宇红 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although there are many kinds of Chinese patent medicines for the treatment of diabetes at present, due to differences in dialectical treatment, compatible prescriptions, dosage forms, processing techniques, etc., the curative effects vary greatly. Good for diabetes

Method used

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  • Chinese medicinal composition for treating diabetes mellitus
  • Chinese medicinal composition for treating diabetes mellitus
  • Chinese medicinal composition for treating diabetes mellitus

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] The granule dosage form of embodiment 1 pharmaceutical composition of the present invention

[0020] Using the conventional method of preparing granules, take 8 parts of Cornus officinalis, 8 parts of Anemarrhena, 9 parts of Rehmannia glutinosa, 3 parts of Coptis chinensis, 6 parts of mulberry leaves, and 6 parts of mulberry branches, soak them in water for 0.5 hours, and then extract them twice, adding 10 parts of water respectively. times, 8 times, the first extraction for 2 hours, the second extraction for 1.5 hours, filtering, combining the filtrates, concentrating, drying, pulverizing, adding an appropriate amount of excipients, mixing, granulating, sieving, and drying to obtain a granular dosage form Pharmaceutical composition preparation.

Embodiment 2

[0021] Tablet dosage form of embodiment 2 pharmaceutical composition of the present invention

[0022] Using the conventional method for preparing tablets, take 6 parts of Cornus officinalis, 6 parts of Anemarrhena, 9 parts of Rehmannia glutinosa, 2 parts of Coptis chinensis, 5 parts of mulberry leaves, and 5 parts of mulberry branches, soak them in 70% ethanol for 0.5 hours, extract twice, add The amount of water was 6 times and 4 times respectively, the first extraction was 2 hours, the second extraction was 1 hour, filtered, combined filtrate, concentrated, dried, crushed, added appropriate amount of auxiliary materials, mixed, granulated, sieved, dried, and The prepared granules are further compressed into tablets and dried to obtain a pharmaceutical composition preparation in the form of tablets.

Embodiment 3

[0023] The capsule dosage form of embodiment 3 pharmaceutical compositions of the present invention

[0024] Using the conventional method of preparing capsules, take 4 parts of Cornus officinalis, 4 parts of Anemarrhena, 5 parts of Rehmannia glutinosa, 1 part of Coptis chinensis, 5 parts of mulberry leaves, and 5 parts of mulberry branches, soak them in 60% ethanol for 0.5 hours, extract twice, add The amount of water is 7 times and 5 times respectively, the first extraction is 2 hours, the second extraction is 1 hour, filtered, combined filtrate, concentrated, dried, crushed and then added appropriate amount of excipients, mixed, granulated, sieved, dried, the The prepared granules are packed into capsule shells to make capsules, that is, the pharmaceutical composition preparations in the form of capsules are made.

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Abstract

The invention discloses a Chinese medicinal composition for treating diabetes mellitus and a preparation thereof. The Chinese medicinal composition is prepared to form a certain preparation in the following steps: extracting and separating mulberry twig, mulberry leaf, dogwood, rhizoma anemarrhenae, prepared rehmannia and golden thread with 0 to 75 percent ethanol. The six medicaments are combined, so that the Chinese medicinal composition has the functions of tonifying kidney and consolidating vital energy, nourishing yin and gathering essence, clearing heat and purging intense heat, and reducing blood sugar and quenching thirst, and is used for treating light and moderate diabetes mellitus. Pharmacodynamic researches prove that: the medicinal composition can remarkably reduce the high blood sugar value of a streptozotocin and alloxan induced diabetes mellitus experimental diabetic model, and can remarkably reduce the sugar tolerance of a mice.

Description

technical field [0001] The invention belongs to the technical field of medicine and relates to a medicine or health food for treating diabetes, in particular to a traditional Chinese medicine composition comprising mulberry branches, mulberry leaves, dogwood, Anemarrhena anemarrhena, rehmannia glutinosa and coptis chinensis. Background technique [0002] Diabetes mellitus is a common and frequently occurring endocrine and metabolic disorder disease, which has the characteristics of difficult cure, many complications and high incidence rate. Disorders of glucose metabolism, including fat and protein metabolism, are mainly caused by insufficient secretion or defective action of insulin throughout the body, or both, and are clinically characterized by hyperglycemia, polyuria, polyphagia, and weight loss. Because of its increasing morbidity, disability and mortality, it has become the third largest disease after cardiovascular disease and tumor. The incidence rate in western cou...

Claims

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Application Information

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IPC IPC(8): A61K36/8964A23L1/29A61P3/10A23L33/00
Inventor 王宇红韩远山韩炯
Owner 王宇红
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