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Traditional Chinese medicine for treating postmenopausal osteoporosis and preparation method thereof

A traditional Chinese medicine, quality technology, applied in pharmaceutical formulations, medical preparations containing active ingredients, bone diseases and other directions, can solve the problems of easy to cause complications, curative effect, difficult to popularize the price, difficult to grasp the dose, etc., to achieve a high cure rate, taking Convenience and low cost effect

Inactive Publication Date: 2012-07-04
RUGAO BINJIANG URBAN CONSTR INVESTMENT
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the above-mentioned drugs have obvious toxic effects due to long-term use, and are easy to cause complications, or due to uncertain curative effects, difficult to control the dose, or difficult to popularize due to the price, etc., are not ideal drugs for the treatment of osteoporosis.

Method used

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  • Traditional Chinese medicine for treating postmenopausal osteoporosis and preparation method thereof
  • Traditional Chinese medicine for treating postmenopausal osteoporosis and preparation method thereof

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Experimental program
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Effect test

preparation example Construction

[0066] When the dosage form of the Chinese medicine composition of the present invention is decoction, its preparation method comprises the following steps:

[0067] In the first step, the components are mixed in proportion, crushed and sieved into a powder of 100 mesh to 150 mesh;

[0068] In the second step, add the powder obtained in the first step into cold water and soak for 16 to 20 hours, decoct with a slow fire for 2 to 3 hours, filter the decoction to obtain the first filtrate, the mass of the added water It is 3 to 5 times the mass of the powder obtained in the first step;

[0069] In the third step, add the filter residue obtained by filtering in the second step into cold water again, decoct with a slow fire for 2 hours to 3 hours, and filter to obtain the second filtrate. The quality of the added water is the same as that in the second step;

[0070] In the fourth step, the two filtrates are combined, concentrated to remove part of the water, and the decoction is ...

Embodiment 1

[0085] Acute toxicity experiment and long-term toxicity experiment of embodiment 1 Chinese medicine composition of the present invention

[0086] Acute Toxicity Test

[0087] Experimental drug:

[0088] 18g Achyranthes bidentata, 20g Morinda officinalis, 40g drynaria, 26g dodder, 28g walnut kernel, 35g epimedium, 30g tortoise shell, 23g privet fruit, 16g mulberry, 17g Wujiapi, 16g sumac, 13g Mix Atractylodes Rhizoma Atractylodes Rhizome, 16g rehmannia glutinosa, and 18g Rhizoma Chuanxiong, crush and sieve into 100-mesh powder; add the obtained powder to 1800g cold water and soak for 20 hours, decoct with slow fire for 3 hours, and filter the decoction to obtain No. One filtrate; add the filter residue obtained by filtration into 1800g cold water again, decoct with a slow fire for 3 hours, and filter to obtain the second filtrate; combine the two filtrates, concentrate and remove part of the water to obtain the decoction, the crude drug content is 3g / ml.

[0089] Experimental...

Embodiment 2

[0096] The decoction prepared by embodiment 2 Chinese medicine composition of the present invention

[0097] 18g Achyranthes bidentata, 20g Morinda officinalis, 40g drynaria, 26g dodder, 28g walnut kernel, 35g epimedium, 30g tortoise shell, 23g privet fruit, 16g mulberry, 17g Wujiapi, 16g sumac, 13g Mix Atractylodes Rhizoma Atractylodes Rhizome, 16g rehmannia glutinosa, and 18g Rhizoma Chuanxiong, crush and sieve into 100-mesh powder; add the obtained powder to 1800g cold water and soak for 20 hours, decoct with slow fire for 3 hours, and filter the decoction to obtain No. One filtrate; add the filter residue obtained by filtration into 1800g cold water again, decoct with a slow fire for 3 hours, and filter to obtain the second filtrate; combine the two filtrates, concentrate and remove part of the water to obtain the decoction, the crude drug content is 3g / ml.

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Abstract

The invention provides a traditional Chinese medicine composition for treating postmenopausal osteoporosis. The traditional Chinese medicine composition comprises medicinal cyathula root, morinda officinalis, drynaria rhizome, cuscuta chinensis, walnut kernel, tortoise shell, herba epimedii, parasitic loranthus, cortex acanthopanacis, fructus ligustri lucidi, hematoxylon, bighead atractylodes rhizome, prepared rehmannia root and ligusticum wallichii. After being adopted for treating postmenopausal osteoporosis, the traditional Chinese medicine composition has the advantages that the side effect is small, the curative effect is good, the cost is low, the cure rate is high, the drug resistance is avoided, the taking is convenient, and the like.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition for treating osteoporosis. Background technique [0002] Osteoporosis (Osteoporosis, OP) is a kind of metabolic bone disease characterized by decreased bone mass and destruction of bone microstructure, resulting in increased bone fragility and easy fractures. Currently, nearly 200 million people in the world suffer from this disease. It is a disease whose incidence rate ranks seventh among common diseases and frequently-occurring diseases. In 1941, Albright defined the concept of osteoporosis for the first time in the JAMA magazine. Its basic content is the reduction of osteogenesis, osteoid formation, and the reduction of calcium and phosphorus. The ratio of bone mineral and organic matter is no different from that of normal bone. The narrowing, thinning, and interruption of trabeculae can be inferred to reduce bo...

Claims

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Application Information

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IPC IPC(8): A61K36/804A61P19/10
Inventor 刘思娟
Owner RUGAO BINJIANG URBAN CONSTR INVESTMENT
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