FPGA (field programmable gate array) control-based all-solid-state high-voltage nanosecond pulse generator

Abstract

The invention provides an FPGA (field programmable gate array) control-based all-solid-state high-voltage nanosecond pulse generator, and belongs to the field of bio-electromagnetic technology. The nanosecond pulse generator mainly comprises a power supply system, a pulse forming system, a pulse measurement system, an FPGA control system, a signal conversion system and a portable computer. In the generator, the output pulse amplitude is between 0 and 10kV, the pulse width is between 200 and 1000ns, the pulse frequency is between 1 and 1000Hz, the falling edge is between 30 and 40ns, the number of pulse is between 1 and 1000, and particular parameters are determined according the requirement of tumor treatment. The FPGA control-based all-solid-state high-voltage nanosecond pulse generator has the characteristics of intelligent regulation of pulse parameters (pulse amplitude, width, frequency and number), optical fiber transmission, high parameter accuracy, long service life, small size, low failure rate, good security and the like; and the generator outputs high pulse frequency, and is advantageous to quick searching of the optimal window parameters for inducing tumor cell apoptosis by virtue of intelligent regulation, so that the tumor treatment effect is improved. The FPGA control-based all-solid-state high-voltage nanosecond pulse generator can be widely applied to tumor treatment.

Description

technical field [0001] The invention belongs to the field of bioelectromagnetic technology, in particular to an all-solid-state high-voltage nanosecond square-wave pulse generator based on Field Programmable Gate Array (FPGA) control. Background technique [0002] At present, nanosecond pulse power technology is being more and more widely used in research fields such as high-tech research, high-tech and civil industry, mainly in oil exploration, accelerators, excimer lasers, particle beams, electron beams and medical technology Applied research in other fields. As far as the biomedical field in the civilian field is concerned, the influence of nanosecond pulsed electric fields on cell structure and function and its therapeutic effect on organisms have become research hotspots in the field of bioelectromagnetic technology. Studies have shown that when the pulse width is reduced to the nanosecond (ns) level and the electric field strength is increased to 10kV / cm and above, th...

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Problems solved by technology

The main disadvantages of this device are: a spark gas switch is used as the main switch, and the maintenance and replacement costs are high, which limits the service life of the device; the output pulse repetition frequency is low, which is not conducive to the selection of nanosecond pulse electric field electro-treatment effect window parameters in tumor cells ;The output pulse pulse width adjustment needs to increase or decrease the network module manually, it is difficult to realize the accurate display and adjustment of the pulse parameters, which is not conducive to the real-time adjustment of the pulse parameters; it needs a high-precision load resistance to match it to output a square wave pulse , which limits the use of the device

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