Preparation method for schefflera arboricola hayata total saponins

Abstract

The invention relates to a preparation method for schefflera arboricola hayata total saponins, which is simple and convenient in operation, low in pollution and low in equipment investment. The preparation method comprises the following technical steps of: performing reflux extraction 2-3 times on crude powder of paris polyphylla stems with ethanol of which the concentration is 60 to 90 percent for 1.5 hours at each time, wherein the amount of the ethanol is 10 to 12 times that of the crude powder; combining the extract; filtering the extract; reclaiming the ethanol under reduced pressure and concentrating the ethanol; degreasing the extract by adding sherwood oil into the extract; adding water into the residue until the volume is 1 to 2 times that of the medicinal material; concentrating the solution with a nanofiltration membrane; drying the concentrated solution; recrystallizing the concentrated solution by adding acetone into the concentrated solution; and filtering and washing the crystal to obtain the schefflera arboricola hayata total saponins. The schefflera arboricola hayata total saponins prepared by the method are high in purity and industrial mass production is easy to realize.

Description

technical field [0001] The invention relates to a preparation method of total saponins of aescin, in particular to a method for extracting total saponins of aescin. Background technique [0002] Aescin is also called Aescin, Chonglou, and flea rest. Aescin saponin is derived from the dried rhizome of Aescinus aesculus, a plant of the Liliaceae family. It has the effects of clearing away heat and detoxifying, reducing swelling and relieving pain. Folks are mostly used to treat unknown swollen poison and poisonous snake bites, as well as mumps, tonsillitis, sore throat, mastitis, bruises, etc. [0003] Aescin rhizomes contain diosgenin-3-O-α-D-glucopyranoside (diosgenin-3-O-α-D-glucopyranoside), namely polyphyllin A, diosgenin-3 -O-α-L rhamnopyranosyl (1→4)-β-D-glucopyranoside, pariphyllin [2], pariphyllin A, B, dioscin [ 4], Aescin C, D, E, F[5], G, H, Diosgenin-3-O-α-L-arabinofuranosyl-(1→4)-[α-L -rhamnopyranosyl-(1→2)β-D-glucopyranosyl, diosgenin-hexaacetoxy-3-O-α-L-rha...

AI Technical Summary

Problems solved by technology

[0004] There are few studies on escin in the prior art. Cui Yan et al. "Research on the Separation and Structural Identification of Dioscin in Aescin" mentioned the method of separating different dioscins by silica gel column chromatography, which is not for production purposes. , the batch size is small, not suitable for scale-up

Extraction method of dioscin from Aescinus chinensis with low yield and low purity