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Chinese medicinal extract for eliminating face red blood streaks and preparation method and application thereof

A technology of extract and traditional Chinese medicine, which is applied to the traditional Chinese medicine extract for removing facial redness and the field of preparation and application thereof, can solve the problems of inability to accurately define effective components, loss of elasticity of surface skin, and rigidity of capillaries, and achieves reduction of blood vessel permeability. The effect of enhancing skin moisture content and regulating immune function

Active Publication Date: 2012-04-04
BEIJING TECHNOLOGY AND BUSINESS UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, the means of treating red blood streaks at home and abroad are mainly based on the physical method of laser treatment, which violates the natural laws of skin metabolism and compulsively removes red blood streaks at one time, resulting in capillary stiffness, loss of elasticity of the surface skin, and even agglomeration, Pigmentation, easy to relapse; Another method is oral drug treatment, which is three-point poisonous, and the efficacy of traditional Chinese medicine is mostly multi-faceted, and the active ingredients cannot be accurately defined

Method used

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  • Chinese medicinal extract for eliminating face red blood streaks and preparation method and application thereof
  • Chinese medicinal extract for eliminating face red blood streaks and preparation method and application thereof
  • Chinese medicinal extract for eliminating face red blood streaks and preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] Embodiment 1, preparation Chinese medicine extract

[0030] The production process flow chart of traditional Chinese medicine extract is as follows: figure 1 As shown, the specific process is as follows:

[0031] The ratio of material to liquid is 1:10, that is, a mixture of 88g rhubarb, pagoda japonica, astragalus, and chamomile (all with a particle size of 60-80 mesh), of which, 45 grams of rhubarb, 20 grams of pagoda japonica, 17.5 grams of astragalus, and 5.5 grams of chamomile , then add 1000mL propylene glycol; ultrasonically extract for 45min (cover with plastic wrap to reduce evaporation) (ultrasonic frequency is 50KHz), the temperature is 75°C; stop heating, cool to 40°C in water circulation, coarse filter with 200 mesh gauze; 4000r / min speed Centrifuge for 10 minutes to get the supernatant; vacuum diatomaceous earth filter cake suction filter the supernatant, collect the suction filtrate, which is the Chinese medicine extract solution (denoted as the extract ...

Embodiment 2

[0032] Embodiment 2, preparation Chinese medicine extract

[0033] The production process flow chart of traditional Chinese medicine extract is as follows: figure 1 As shown, the specific process is as follows:

[0034] The material-to-liquid ratio is 1:15, that is, a mixture of 105g of rhubarb, pagoda japonica, astragalus, and chamomile (all with a particle size of 60-80 mesh), of which, 50 grams of rhubarb, 25 grams of pagoda, 20 grams of astragalus, and 10 grams of chamomile , then add 1500mL propylene glycol; ultrasonically extract for 60min (cover with plastic wrap to reduce evaporation) (ultrasonic frequency is 30KHz), the temperature is 65°C; stop heating, cool to 40°C with water circulation, coarse filter with 200 mesh gauze; 4000r / min speed Centrifuge for 10 minutes, and take the supernatant; vacuum diatomaceous earth filter cake suction filter the supernatant, collect the suction filtrate, which is the Chinese medicine extract solution (denoted as the extract soluti...

Embodiment 3

[0035] Embodiment 3, the functional assay test of Chinese medicine extract

[0036] The Chinese medicine extract solution used in the following test is to record the Chinese medicine extract solution prepared in Example 1 as the extract solution with a concentration of 100%, and the extract solutions with other concentrations are obtained by diluting the solution accordingly.

[0037] 1. Determination of ability to reduce capillary permeability

[0038] The determination method is carried out according to the method in the following literature: Zhuang Shufei, Zhou Caihong, Qian Jing, Qian Mu, SHIBUYAMasabumi, Ye Qizhuang, New method for random screening of inhibitors of vascular endothelial growth factor receptor I kinase, Chinese Pharmacological Journal, 2002 No. 23:117-123.

[0039] As a growth factor, VEGF binds to the cell surface part of its receptor Flt1, promotes the receptor from a dormant state to an active state, undergoes autophosphorylation, and activates phosphat...

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Abstract

The invention discloses a Chinese medicinal extract for eliminating face red blood streaks and a preparation method and application thereof. The Chinese medicinal extract is extracted from a Chinese medicinal composition which consists of rhubarb, pagoda tree flower bud, astragalus and matricaria chamomilla according to the weight part ratio (30-50):(15-25):(15-25):(5-15). The preparation method comprises the following steps of: smashing the rhubarb, pagoda tree flower bud, astragalus and matricaria chamomilla in the ratio; adding propylene glycol serving as an extracting agent for soaking; performing ultrasonic extraction; cooling; filtering and centrifuging; and performing suction filtration, and extracting supernate to obtain the Chinese medicinal extract. The extraction and separationmethod of the Chinese medicinal extract provided by the invention is simple and convenient, the obtained product has high purity, and the product quality is improved greatly. The used Chinese medicinal composition has the effects of reducing the blood vessel permeability, restoring microcirculation, regulating the immunologic function, promoting skin metabolism, increasing collagen and elastin, and the like, so that the extract of the Chinese medicinal composition can be taken as an additive for eliminating face red blood streaks.

Description

technical field [0001] The invention relates to a traditional Chinese medicine extract for removing facial red blood streaks, a preparation method and application thereof. Background technique [0002] Red blood streaks are facial phenomena caused by poor facial telangiectasia, damaged stratum corneum, or superficial position of some capillaries. The threads are criss-crossed, like spider webs, dispersedly distributed, and in severe cases, they will be connected into flakes and become red face. The face of patients with facial red bloodshots looks redder than normal skin color, and some of them only have redness on both sides of the palate, and the border is round. This kind of skin is thin and sensitive, and it turns red when it is too cold, too hot, or emotionally excited. In severe cases, depositive stains will also form. [0003] At present, the means of treating red blood streaks at home and abroad are mainly based on the physical method of laser treatment, which vio...

Claims

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Application Information

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IPC IPC(8): A61K8/97A61Q19/00
Inventor 董银卯何聪芬赵华刘文婷王领
Owner BEIJING TECHNOLOGY AND BUSINESS UNIVERSITY
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