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Defective total sternum replacement part for total sternum defect operation treatment and method for manufacturing the same

A technique for surgical treatment and production method, applied in the fields of surgery, bone implants, medical science, etc., can solve the problems of small size, easy to produce rejection, insufficient tensile force, etc., to avoid complexity and difficulty, tissue stimulation The effect of less sex and shorter operation time

Active Publication Date: 2012-03-28
江苏金松生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] 2. Artificial materials. There are many kinds. In the early days, there were mainly steel plates, titanium plates, plexiglass plates, steel wire mesh, etc., but the histocompatibility of these materials is poor, it is difficult to fix and loose, and it is not easy to shape and cut. Metal materials especially Metal plates will affect postoperative X-ray examination and radiotherapy, so they have been abandoned in recent years. At present, bone cement and / or autologous tissue materials are often used in bony chest wall repair in the world. This kind of material has good histocompatibility, and cutting plastic It is convenient in shape, easy to sterilize, and does not affect postoperative X-ray examination and radiotherapy, but it still has poor flexibility, poor adhesion to tissues, insufficient tensile strength, and small size, which is limited in the repair of large-area defects. Disadvantages such as expensive
[0006] 3. Most of the biological materials are obtained from animal tissues. For example, Ya Naiquan et al. used self-made bovine pericardium slices + steel mesh to repair 9 cases of chest wall defects with satisfactory results. Pigs were also used as tissue materials. In general, the flexibility of biological materials Good, wide range of sources, strong tensile strength, not easy to age, easy to prepare and store. The disadvantage is that it is antigenic, easy to produce rejection, and the tensile strength is not enough if it is not modified.

Method used

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  • Defective total sternum replacement part for total sternum defect operation treatment and method for manufacturing the same
  • Defective total sternum replacement part for total sternum defect operation treatment and method for manufacturing the same

Examples

Experimental program
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Effect test

Embodiment

[0039] The selected non-degradable materials are molded according to individual requirements by using fusion sinking radical free manufacturing technology. It is then sterilized with ethylene oxide for later use.

[0040] Choose a healthy New Zealand white rabbit dog, after intravenous general anesthesia, endotracheal intubation, mechanical ventilation, bite off the ribs about 1 cm from the sternum, remove the sternum, implant the sternum repair prosthesis, and fix it with the rib stump , Close the chest layer by layer.

[0041] Example result:

[0042] All the rabbits survived the operation without circulatory failure, no dyspnea, and the shape of the thorax was satisfactory. CT examinations at 2, 4, 8, 12, and 24 weeks after operation showed that the ribs were well fixed and the existing sternal shape was maintained, and the broken ends were basically healed at 12 weeks, and the internal fixation materials remained relatively intact at 24 weeks Morphology, no adverse late...

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PUM

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Abstract

The invention relates to a defective total sternum replacement part for total sternum defect operation treatment and a method for manufacturing the same, which relate to the technical field of biological medicine and is characterized in that the defective total sternum replacement part is shaped like residual total sternum without rib, the left side and the right side are provided with independent rib root bones which are in turn alternately reduced from top down, and the lowermost end is provided with connected rib root bones; and clamping grooves with solid inners, four closed sides and front openings are arranged at a place where the rib of the residual total sternum is removed. The manufacturing method comprises the following steps of: drawing three-dimensional form completely complying with the sternum to be replaced by CT three-dimensional imaging technology, and preparing prosthesis as totally same as the sternum to be replaced by non degradable material through fusion deposition free manufacturing technology. The positive results are that special personalized design of the replacement part can maximally recover biology form and function of sternum; and the repair material forms prosthesis as totally same as the individual sternum by using the fusion deposition free manufacturing technology, so that complexity and difficulty of the previous surgery are avoided, operation time is shortened and efficiency is improved.

Description

technical field [0001] The invention relates to the technical field of biomedicine, in particular to a production method of a non-biodegradable repair material used for surgical treatment of total sternal defect. Background technique [0002] The sternum is a flat bone located in the middle of the anterior chest wall, shaped like a short sword, and divided into three parts: hilt, body, and xiphoid process. Both sides of the sternum are connected with the ribs to form the thorax, which plays an important role in protecting the mediastinum and internal organs of the thoracic cavity. Common sternal diseases such as sternal tumors, infections, radiation ulcers, trauma, and congenital deformities often require surgical treatment, resulting in sternal defects. In severe cases, the entire sternum needs to be removed. The integrity and stability of the thoracic cage and the protection of the mediastinal organs were destroyed, endangering the life of the patient. The sternum needs ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61F2/28A61B17/56A61L27/18A61L27/12
Inventor 唐华徐志飞吴彬季明明
Owner 江苏金松生物科技有限公司
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