Preparation method of Huoxiangzhengqi Oral Liquid

Abstract

The invention discloses a method for preparing ageratum oral liquid. The active ingredients of most of prescription medicinal crops are extracted by using a membrane press filtration, cyclic extraction and separation integrated technology in place of a reflux method, a decoction method and a warm immersion method. A process flow can be simplified, the production period can be greatly shortened, energy can be saved, environmental protection and waste residue utilization can be facilitated, and the recovery rate of the active ingredients can be greatly increased.

Description

technical field [0001] The invention belongs to the field of pharmacy and relates to a preparation method of a traditional Chinese medicine preparation. Background technique [0002] Chinese Pharmacopoeia 2010 Edition One Records: Huoxiang Zhengqi Oral Liquid has the effects of relieving the exterior and removing dampness, regulating qi and harmonizing the middle. It is clinically used for colds caused by exogenous wind-cold, internal injury damp stagnation or summer injury and summer dampness. Symptoms include headache, dizziness, Pain in the chest and diaphragm, distending pain in the abdomen, vomiting and diarrhea; gastrointestinal colds with the above syndromes. The prescription is Atractylodes 80g, Chenpi 80g, Magnolia officinalis (made from ginger) 80g, Angelica dahurica 120g, Poria cocos 120g, Dabupi 120g, raw pinellia 80g, licorice extract 10g, patchouli oil 0.8ml, perilla leaf oil 0.4ml . The preparation method is to add 60% ethanol to Magnolia officinalis, heat a...

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Problems solved by technology

In the above methods, the reflux method is used to extract Magnolia officinalis, the decocting method is used to extract raw pinellia, and the 80°C soaking method is used to extract Poria cocos. There are cumbersome processes, long extraction time, high extraction temperature, high energy consumption, easy loss of heat-sensitive components, and dissolution of impurities. More, low recovery rate of active ingredients, troublesome post-processing, etc.

In addition, in the above method, the raw pinellia is soaked in water until it penetrates the heart, and then the dried ginger is added to the water and decocted. The disadvantages are: (1) Even if the dried pinellia is divided into different sizes and soaked until the heart is penetrated, it is difficult to achieve Very few pinellia tubers that are particularly large are soaked to the core. When the small pinellia tubers have already soaked, the extra large pinellia tubers are far from being penetrated. Repeated water changes and soaking will not only cause a large loss of active ingredients, but also easily cause small tubers to soak and rot The phenomenon of smelly and sour, the whole soaking process can last for several days; (2) Because Pinellia is rich in starch, when the cooking temperature is close to 100℃, the outer starch of Pinellia has already gelatinized, which will seriously hinder Dissolution of active ingredients in Pinellia tissue cells

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