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Microcapsule soft capsule preparation with high alpha-linolenic acid content

A technology of soft capsule preparation and linolenic acid, which is applied in capsule delivery, medical preparations containing active ingredients, food preparation, etc. It can solve the problems of less research on water-soluble substances, and achieve masking of bad smell, improvement of taste, and prevention of decomposition Effect

Active Publication Date: 2011-10-12
SHANGHAI FUDAN AOYI MEDICAL TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the research on the encapsulation technology of non-water-soluble substances is relatively mature, while the encapsulation technology of water-soluble substances is relatively less

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0052] Take water-soluble nutrients: zinc citrate 10Kg, vitamin B 1 5Kg, Vitamin B 2 6Kg, Vitamin B 6 4Kg, vitamin C15g, folic acid 0.05Kg, mix evenly, ZMD-80 type low-temperature ultrafine pulverizer for ultrafine pulverization, control the output particle size within 15μm, suspend the ultrafine powder water-soluble nutrients in WBF-250 multifunctional fluidization On the bed, mix and dissolve 5Kg gelatin and 10Kg ethanol solution, and add 0.1Kg magnesium stearate to form a film solution, spray on the top, spray at a temperature of 60°C to form a film, and evenly cover the above water-soluble nutrients to obtain Microcapsules.

Embodiment 2

[0054] Take water-soluble nutrients: zinc citrate 12Kg, vitamin B 1 6Kg, Vitamin B 26Kg, Vitamin B 6 6Kg, vitamin C12Kg, folic acid 0.08Kg, mix evenly, ZMD-80 type low-temperature ultrafine pulverizer for ultrafine pulverization, control the output particle size within 15μm; suspend the ultrafine powder water-soluble nutrients in WBF-250 multifunctional fluidization On the bed, mix and dissolve 6Kg gum arabic and 11Kg ethanol solution, and add 0.08Kg magnesium stearate to form a film solution, spray on the top, spray at a temperature of 65°C to form a film, and evenly cover water-soluble nutrients. Microcapsules.

Embodiment 3

[0056] Take water-soluble nutrients: zinc citrate 14Kg, vitamin B 1 6Kg, Vitamin B 2 4Kg, Vitamin B 6 4Kg, vitamin C8Kg, folic acid 0.03Kg, mix evenly, ZMD-80 type low-temperature ultrafine pulverizer for ultrafine pulverization, control the output particle size within 15μm, take ultrafine powder water-soluble nutrients and suspend them in WBF-250 multifunctional fluidization On the bed, mix and dissolve 2Kg gum arabic and 3Kg gelatin with 8Kg ethanol solution, and add 0.07Kg magnesium stearate to form a film solution, spray on the top, spray at a temperature of 65°C to form a film, and evenly cover water-soluble nutrients , to produce microcapsules.

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PUM

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Abstract

The invention provides a microcapsule soft capsule preparation with a high alpha-linolenic acid content. The active ingredients of the preparation comprise high-content alpha-linolenic acid as the main nutritional ingredient and other nutritional ingredients such as oil-soluble nutritional ingredients and water-soluble nutritional ingredients, wherein the water-soluble nutritional ingredients are prepared into microcapsules by an encapsulating material. The alpha-linolenic acid content of the microcapsule soft capsule preparation with a high alpha-linolenic acid content provided by the invention is 50-60%. The microcapsule soft capsule preparation provided by the invention overcomes the defects of the existing preparations, effectively improves the stability of the product, reserves the contents of various nutritional ingredients, improves the bioavailability, reduces the dosage, flavors disagreeable tastes and has a better taste.

Description

technical field [0001] The invention relates to nutrition and health care products, in particular to a nutrition and health care product for invigorating the brain and improving intelligence, in particular to a microencapsulated soft capsule preparation with high content of α-linolenic acid. Background technique [0002] Nutrients are of great significance to maintaining human growth and development and ensuring health. Brain-invigorating nutritional health products have a certain health care effect on promoting human brain development and intellectual development, and at the same time can enhance memory function and improve the quality of life of the elderly. Therefore, it is favored by people. α-linolenic acid is one of the most basic raw materials for nerve cell synthesis. It can directly affect the physical and chemical properties of nerve cells, increase the fluidity of membranes, promote and increase the release of neurotransmitters and nerve conduction speed. [000...

Claims

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Application Information

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IPC IPC(8): A61K9/48A61K45/00A61K31/202A61K31/685A61P3/02A61P25/00A23L1/29A61K31/194A61K31/51A61K31/525A61K31/4415A61K31/375A61K31/519A61K31/07A61K31/557A23L33/00
Inventor 尤俊涂宏建
Owner SHANGHAI FUDAN AOYI MEDICAL TECH
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