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Traditional Chinese medicine composition for treating neurasthenia, and preparation method thereof

A technology for neurasthenia and composition, applied in the directions of drug combination, pharmaceutical formula, nervous system diseases, etc., can solve the problems of unsatisfactory curative effect, low cure rate, easy recurrence, etc.

Active Publication Date: 2011-09-28
陕西汉唐制药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

There are many Chinese patent medicines in the treatment of neurasthenia in traditional Chinese medicine, but the curative effect is not satisfactory
Ministry-issued standard "Prescriptions of Traditional Chinese Medicine" Volume 12 WS 3 - "Jiannao Anshen Tablet" under item B-2407-97 is a pure traditional Chinese medicine preparation. After years of clinical application, the drug has achieved certain curative effect in the treatment of neurasthenia. Not ideal, low cure rate, easy to relapse; as sugar-coated tablets, diabetes patients take it and other shortcomings that cannot be ignored
[0005] The volatile oil in the jujube seed has a very good sedative effect, but the volatile oil in the jujube kernel has not been extracted during the extraction process of the "Jiannao Anshen Tablet" preparation process, and the loss is relatively large, which is a pity

Method used

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  • Traditional Chinese medicine composition for treating neurasthenia, and preparation method thereof
  • Traditional Chinese medicine composition for treating neurasthenia, and preparation method thereof
  • Traditional Chinese medicine composition for treating neurasthenia, and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0111] Formula ratio:

[0112]

[0113] Tablet preparation method:

[0114] The above sixteen flavors, 10g red ginseng, 4g antler, 10g antler gum, 25g antler cream and 40g poria cocos are crushed into fine powder, sieved and mixed; Add 50% ethanol for reflux extraction twice, add 13 times the amount for the first time, reflux for 2 hours, add 11 times the amount for the second time, reflux for 1.5 hours, filter, combine the filtrates, and recover ethanol, at -0.07~-0.08mpa Thick paste with a relative density of 1.31 to 1.32 when concentrated under reduced pressure to 80°C; 40g of fried jujube kernels, broken, and 40g of Rehmannia glutinosa, 40g of Radix Radix Radix, 235g of steamed Polygonatum, 80g of Polygala, 80g of pitted jujube, and decocted with water For the second time, add 12 times the amount for the first time, decoct for 4 hours, add 10 times the amount for the second time, and decoct for 4 hours, collect the distilled oil-water mixture during the two decoctions ...

Embodiment 2

[0116] Formula ratio:

[0117]

[0118] Capsule preparation method:

[0119] The above sixteen flavors, 10g red ginseng, 4g antler, 10g antler gum, 25g antler cream and 40g poria cocos are crushed into fine powder, sieved and mixed; Add 50% ethanol for reflux extraction twice, add 13 times the amount for the first time, reflux for 2 hours, add 11 times the amount for the second time, reflux for 1.5 hours, filter, combine the filtrates, and recover ethanol, at -0.07~-0.08mpa Thick paste with a relative density of 1.31 to 1.32 when concentrated under reduced pressure to 80°C; 40g of fried jujube kernels, broken, and 40g of Rehmannia glutinosa, 40g of Radix Radix Radix, 235g of steamed Polygonatum, 80g of Polygala, 80g of pitted jujube, and decocted with water For the second time, add 12 times the amount for the first time, decoct for 4 hours, add 10 times the amount for the second time, and decoct for 4 hours, collect the distilled oil-water mixture during the two decoctions...

Embodiment 3

[0121] Formula ratio:

[0122]

[0123] Granule preparation method:

[0124] The above sixteen flavors, 10g red ginseng, 4g antler, 10g antler gum, 25g antler cream and 40g poria cocos are crushed into fine powder, sieved and mixed; Add 50% ethanol for reflux extraction twice, add 13 times the amount for the first time, reflux for 2 hours, add 11 times the amount for the second time, reflux for 1.5 hours, filter, combine the filtrates, and recover ethanol, at -0.07~-0.08mpa Thick paste with a relative density of 1.31 to 1.32 when concentrated under reduced pressure to 80°C; 40g of fried jujube kernels, broken, and 40g of Rehmannia glutinosa, 40g of Radix Radix Radix, 235g of steamed Polygonatum, 80g of Polygala, 80g of pitted jujube, and decocted with water For the second time, add 12 times the amount for the first time, decoct for 4 hours, add 10 times the amount for the second time, and decoct for 4 hours, collect the distilled oil-water mixture during the two decoctions...

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Abstract

The invention relates to a traditional Chinese medicine composition for treating neurasthenia, and a preparation method thereof. The traditional Chinese medicine composition is prepared from the following sixteen traditional Chinese medicines: steamed sealwort, epimedium, wolfberry fruit, antler, deerhorn glue, deglued deerhorn, red ginseng, pitted jujube, tuckahoe, ophiopogon root, tortoise shell, fried wild jujube seed, magnolia vine fruit, prepared polygala root, prepared rehmannia root and cocklebur fruit. The traditional Chinese medicine composition has the efficacies of strengthening bymeans of tonics and tranquilizing and allaying excitement, and is mainly used for treating neurasthenia, headache, dizziness, amnesia, insomnia, tinnitus and the like. Compared with the prior art, the traditional Chinese medicine composition has a more reasonable process, high bioavailability, good drug stability and no toxic side effects, and is notably improved on the clinical pharmacodynamic testing effects.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition for treating neurasthenia and a preparation method thereof, belonging to the technical field of pharmacy. technical background [0002] Neurasthenia is a class of neurotic disorders characterized by easy excitement and mental fatigue, emotional troubles and psychological symptoms. Neurasthenia is often accompanied by dizziness, headache, vertigo, tinnitus, palpitations, irritability and irritation, difficulty falling asleep, anxiety and depression, and impotence, premature ejaculation or menstrual disorders. [0003] With the rapid development of society and the continuous acceleration of people's life rhythm, people's life, study, and work pressure are increasing, and people are prone to mental weakness, which seriously affects people's health. [0004] At present, Western medicine mainly treats neurasthenia by taking sleeping pills, but clinical addiction and drug resistance are pro...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/896A61K9/16A61K9/20A61K9/48A61P25/00A61K35/32A61K35/56A61K35/586
Inventor 肖军
Owner 陕西汉唐制药有限公司
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