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Method for eliminating deformation of polypropylene transfusion bottle

An infusion bottle and polypropylene technology, applied in the field of a method to solve the deformation of the infusion bottle, can solve the problems of the quality of the infusion bottle, the deformation of the PP infusion bottle, and the impact of use, so as to improve the ability to resist external pressure and prevent the bottle from shrinking , to solve the effect of deformation

Active Publication Date: 2012-11-14
SICHUAN KELUN PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The altitude of our country is high in the west and low in the east. The PP infusion bottle produced in the high altitude area will shrink and deform when it reaches the low altitude plain area, which will have a certain impact on the use, and it is easy to give people the illusion that the quality of the infusion bottle is problematic. Therefore, it is necessary to Solve the "fly in the ointment" that PP infusion bottles produced in plateau areas are deformed in low-altitude plain areas

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0018] Embodiment 1: 500ml sodium chloride injection filling

[0019] (1) The temperature of the filling liquid is 28°C;

[0020] (2) Sterilize with a sterilization temperature of 115°C, 30 minutes, and a pressure coefficient of 5.5 (0.26Mpa). Sterilization starts at 00:47 and starts with a pressure of 0.26Mpa when the sterilization temperature reaches 80°C Keep the pressure, keep the pressure until the sterilization cools down to 80°C and start to release the pressure, and exit when the temperature drops to 50°C at 02:55;

[0021] (3) After coming out of the cabinet, the product is full and the bottle shape is more beautiful. The pressure inside the bottle is tested to be between 0.010-0.015Mpa, which improves the bottle's ability to resist external pressure and ensures that the bottle shape does not deform.

Embodiment 2

[0022] Embodiment 2: 100ml5% glucose injection filling;

[0023] (1) The temperature of the filling liquid is 30°C;

[0024] (2) Sterilize with a sterilization temperature of 115°C, 30 minutes, and a pressure coefficient of 4.8 (0.24Mpa). Sterilization starts at 06:24 and begins to use a pressure of 0.24Mpa when the sterilization temperature reaches 80°C Keep the pressure until the sterilization temperature drops to 80°C and start to release the pressure, and come out of the cabinet when the temperature drops to 50°C at 07:54;

[0025] (3) After coming out of the cabinet, the product is full and the bottle shape is more beautiful. The pressure inside the bottle is tested to be between 0.010-0.015Mpa, which improves the bottle's ability to resist external pressure and ensures that the bottle shape does not deform.

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PUM

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Abstract

The invention relates to the field of medical appliances, in particular to a method for eliminating the deformation of a polypropylene transfusion bottle. The method is characterized by comprising the following steps of: lowering the temperature of a liquid medicament to 25-30 DEG C during dispensation in a preparation procedure; welding a cover by adopting a non-exhausting way in a filling procedure; maintaining pressure under the pressure of between 0.26 MPa and 0.28 MPa when the temperature is raised to 80 DEG C in a sterilizing procedure; maintaining pressure by using the pressure coefficient of between 0.26 MPa and 0.28 MPa at a heat preserving stage in the sterilizing procedure; maintaining pressure at 80 DEG C under the pressure of between 0.26 MPa and 0.28 MPa at a cooling stage in the sterilizing procedure, for exhausting; and lowering the temperature below 50 DEG C in the sterilizing procedure for discharging. In the invention, the characteristics of a polypropylene material are utilized, solution preparation, filling and sterilizing processes are improved, and low-temperature filling is adopted, so that the contraction of the bottle caused by over-high temperature of the liquid medicament is prevented; and the external pressure resistance of the bottle is improved to prevent the bottle from being deformed, and the problem of deformation of the polypropylene transfusion bottle, which is produced in a high-altitude region, in a low-altitude region is solved.

Description

technical field [0001] The invention relates to the field of medical equipment, in particular to a method for solving the deformation of an infusion bottle. Background technique [0002] At present, the infusion bottle is mainly made of polypropylene material, that is, PP. PP is a semi-crystalline polymer material, which is harder and has a higher melting point than PE. Due to the higher crystallinity, the surface stiffness and resistance of this material The scratch property is very good. Due to crystallization, the shrinkage rate of PP is quite high, generally 1.8~2.5%. The reason is that there is a certain gap between the molecules of the polymer material. The size of the gap has a lot to do with the material structure and temperature. , but as long as there is a gap, the temperature rises, the thermal motion of the material molecules has an upward trend, and the molecular potential energy is also increasing, so the volume of the material is increasing. On the contrary, a...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): B67C3/02
Inventor 刘懿鑫肖宇高国辉
Owner SICHUAN KELUN PHARMA CO LTD
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