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Tinidazole vaginal effervescent tablet and preparation method thereof

A technology of tinidazole and effervescent tablets, which is applied in the field of tinidazole vaginal effervescent tablets and its preparation, can solve problems such as unreasonable drug prescriptions, and achieve the effects of prolonging the action time of pathogenic microorganisms, reducing loss, and increasing residence time Effect

Inactive Publication Date: 2011-05-11
赵磊
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] But existing effervescent tablets have the following problems:? Irrational drug prescription

Method used

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Examples

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Effect test

Embodiment Construction

[0036] Below in conjunction with embodiment the present invention is described further.

[0037] A kind of tinidazole vaginal effervescent tablet, it comprises the following composition by weight:

[0038] Tinidazole 200 parts

[0039] Tartaric acid 105 parts

[0040] Calcium lactate 40 parts

[0041] Lactic acid 44 parts

[0042] Starch 150 parts

[0043] Povidone K30 6.5 parts

[0044] Silica 20 parts

[0045] Sodium bicarbonate 120 parts

[0046] Polyethylene glycol 4000 60 parts

[0047] Sodium Lauryl Sulfate 4 parts

[0048] Magnesium stearate 4 parts

[0049] The pH buffering substance is lactic acid / calcium lactate.

[0050] The effervescent disintegrating agent is composed of an alkali component and an acid component, wherein the alkali component is sodium bicarbonate; the acid component is tartaric acid.

[0051] The water-soluble macromolecular substance encapsulates the acid component or base component of the effervescent disintegrating agent, such as pov...

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Abstract

The invention relates to a tinidazole vaginal effervescent tablet and a preparation method thereof. The tinidazole vaginal effervescent tablet has the advantages of simple preparation method, good treatment effect and the like. The tinidazole vaginal effervescent tablet comprises the following components in parts by weight: 200 parts of tinidazole, 105 parts of tartaric acid, 40 parts of calcium lactate, 44 parts of lactic acid, 150 parts of starch, 6.5 parts of polyvidone K30, 20 parts of silicon dioxide, 120 parts of sodium bicarbonate, 60 parts of polyethylene glycol 4000, 4 parts of lauryl sodium sulfate and 4 parts of magnesium stearate.

Description

technical field [0001] The invention relates to a tinidazole vaginal effervescent tablet and a preparation method thereof. Background technique [0002] Gynecological inflammation refers to diseases caused by women's reproductive system infection, mainly divided into three categories: vaginitis, cervicitis and pelvic inflammatory disease. According to the incomplete statistics of the World Health Organization, the incidence rate of various gynecological diseases among women is more than 65%. my country's relevant data survey shows that the incidence of gynecological diseases in women of childbearing age is above 70%. Almost 100% of women suffer from different degrees of vaginitis in their lifetime, and more than 5% of them have seriously affected normal work and life because of the illness. Drugs for the treatment of gynecological inflammation have huge market demand potential, and have become a must for forward-looking drug research and development institutions and manufa...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/46A61K31/4164A61P15/00A61P15/02A61P31/02
Inventor 赵磊
Owner 赵磊
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