Composite antioxidant for improving semen quality of male animal

A compound antioxidant and male technology, applied in the field of compound antioxidants, can solve problems such as impact on sperm motility, safety concerns, and uncertain effects, and achieve a strong protective barrier, improve sperm motility, and increase sperm count.

Active Publication Date: 2013-05-08
SHANGHAI XINNONG FEED
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Some researchers believe that a single addition of dihydropyridine can increase the amount of ejaculation, but it has little effect on sperm motility, and the safety of long-term use of high-dose synthetics is worrying; inconvenient and ineffective

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] The components of this example and their percentages by weight are: 50% vitamin E 7.0%, 92% vitamin C 13.0%, 20% tea polyphenol 30.0%, 95% lipoic acid 5.0% %, corn cob powder (carrier) 45.0%, after fully stirring, obtain compound antioxidant, add 1.5g compound antioxidant to feed 36 adult SPF grade SD male rats in every kg feed, after feeding for 22 days, rat serum The SOD enzyme activity in the serum increased by 11.8% (234.07U / ml: 198.36U / ml), the NO free radical in the serum decreased by 12.08% (29.28: 33.30umol / ml), and the serum malondialdehyde (MDA) content decreased by 15.2% (6.63: 7.82nmol / ml), the sperm count of rat semen increased by 34.7% (30.64×10 5 / ml: 22.75×10 5 / ml), the number of a-class sperm increased by 27.0% (6.32×10 5 / ml: 4.98×10 5 / ml), sperm motility increased by 10.3% (89.06%: 80.75%).

Embodiment 2

[0021] The components of this example and their percentages by weight are: 50% vitamin E 8.0%, 92% vitamin C 15.0%, 20% tea polyphenol 20.04%, 95% lipoic acid 4.0%, corn cob powder (carrier) 53.0%, obtain composite antioxidant after fully stirring, add 2.0g composite antioxidant in every kg feed and feed 20 70 day old male mice, feed the mouse serum after 21 days The SOD enzyme activity in the medium increased by 4.8% (226.96U / ml: 216.57U / ml), the serum GSH-Px activity increased by 4.7% (2931.83U / ml: 2800.22U / ml), and the serum NO content decreased by 25.07% (21.53μmol / L : 28.73μmol / L), serum malondialdehyde (MDA) content decreased by 18.1% (5.91nmol / L: 7.22nmol / L), testosterone concentration in mouse serum increased by 51.51% (834.14U / ml: 550.53U / ml) , the sperm count of mouse semen increased by 15.2% (30.18×10 6 / ml: 26.2×10 6 / ml), the number of a-class sperm increased by 16.2% (8.59×10 6 / ml: 7.40×10 6 / ml), sperm motility increased by 7.5% (93.3%: 86.8%).

Embodiment 3

[0023] The components of this example and their percentages by weight are: 50% vitamin E 8.5%, 92% vitamin C 12.0%, 20% tea polyphenols 40.0%, 95% lipoic acid 5.0%, corncob powder (carrier) 34.5%, after fully stirring, obtain composite antioxidant, add 2.0g composite antioxidant in every kg feed and feed 15 adult breeding boars, the amount of semen of boars after feeding for 45 days Increased by 7.54% (216.7ml: 200.3ml), sperm count increased by 11.86% (176 million / ml: 158 million / ml), and sperm motility increased by 7.27% (78.21%: 72.91%).

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Abstract

The invention relates to a composite antioxidant for improving reproductive capacity of a male animal, which belongs to the technical field of animal feed and comprises the following components by weight percent: 6.5-8.5% of food grade vitamin E, 11.0-15.5% of food grade vitamin C, 20.0-40.0% of food grade tea polyphenols, 4.0-6.0% of food grade thioctic acid and the balance of food grade corncobpowder which is taken as a carrier. The composite antioxidant can significantly reduce the content of nitrogen oxide free radicals and malonaldehyde in serum, improve the activity of SOD enzyme, significantly increase the number of sperms and the number of a grade sperms (the sperms with strong activity) in a male rat and improve the reproductive capacity of the male animal.

Description

technical field [0001] The invention relates to a compound antioxidant in the technical field of animal feed, in particular to a compound antioxidant for improving the quality of male animal semen. Background technique [0002] A large number of studies have proved that due to adverse environmental conditions such as high temperature, air, etc., unreasonable food structure, excessive intake of synthetic compounds or drugs affect the reproductive health of male animals. [0003] The quality of semen is the main factor affecting the reproductive ability of male animals, and the sperm, especially the plasma membrane, is rich in unsaturated fatty acids. The presence of unsaturated fatty acids is conducive to maintaining the fluidity of the membrane, and the fluidity of the membrane is the key to sperm movement, acrosome Necessary for fertilization processes such as reaction and sperm-egg fusion. However, these polyunsaturated fatty acids are easily oxidized under aerobic condit...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A23K1/18A23K1/16A23K10/30A23K20/174A23K50/00
Inventor 徐建雄陈小连
Owner SHANGHAI XINNONG FEED
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