Synthetic micromolecule compound capable of conveying bioactive substances and application thereof

Abstract

The invention relates to a synthetic micromolecule compound capable of conveying bioactive substances and application thereof. The general formula of the micromolecule compound or any medicinal salt thereof is disclosed in the specification, wherein R4 is an aromatic ring of C6-C10 or a heteroaromatic ring of C2-C9; R5 is a -(CH2)n-, a naphthenic group of C3-C5, an aromatic ring of -(CH2)n-C6-C10or a heteroaromatic ring of C2-C9; and R6 is a carboxyl group (COOH), -CONHOH, tetrazole, OH and -SO3H.

Description

This application is a divisional application with an application date of May 22, 2009, an application number of 200910043494.0, and an invention title of "Synthetic Small Molecular Compounds Capable of Transporting Biologically Active Substances and Their Applications". technical field The present invention relates to a small molecular compound capable of transporting biologically active substances (including chemically synthesized active substances) into organisms and applications thereof. Background technique Substances with biological activity can be transported into organisms through several ways, but which method can achieve the purpose of delivery is often subject to the objective conditions of delivery. Most of the biologically active substances (such as calcitonin, interferon, insulin, special mucopolysaccharides, heparin, heparin analogs, etc.) Relatively single, and frequent administration, poor patient compliance. Currently, the biggest problem with oral admin...

AI Technical Summary

Problems solved by technology

However, in these microparticle carrier delivery systems, the lipid drug delivery system cannot achieve a high encapsulation efficiency for hydrophilic macromolecular drugs

In addition, they are less stable in the digestive tract

Ordinary liposomes and microemulsions are basically unable to meet the oral delivery of hydrophilic macromolecular drugs