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Compound combination medicament for treating asthma and preparation method thereof

A drug and compound technology, which is applied in the field of compound combination drugs for the treatment of bronchial asthma and its preparation, can solve the problems of inability to popularize and use, the compatibility of prescriptions, and poor effects, and achieve complete curative effect, easy operation, and short course of treatment.

Inactive Publication Date: 2011-01-12
JIANGSU PROVINCIAL HOSPITAL OF TCM
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

There are currently flaws in TCM syndrome differentiation. Cold wheezing and hot wheezing are not mostly symptoms of asthma, while wind-phlegm wheezing is more common, but their prescriptions have poor compatibility and effects and cannot be popularized.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0015] A compound combination medicine for treating asthma, comprising the following components in parts by weight: 40 parts of Shegan, 50 parts of Zhimahuang, 90 parts of Gualou, 50 parts of Scallop (stir-fried), 60 parts of silkworm (stir-fried), white peony root (Fried) 50 parts, 90 parts of Tinglizi, 30 parts of roasted licorice, 100 parts of earthworm, 90 parts of cnidium, 150 parts of clam shell, 50 parts of bitter almond, 50 parts of ground maple skin, 50 parts of sea wind vine, 100 parts of peach kernel Parts, 30 parts of Scutellaria baicalensis, altogether sixteen herbs.

[0016] Weigh the above sixteen herbs in parts by weight, add 5 times of water to soak for 60 minutes, decoct 3 times for 2 hours each time, filter, combine the filtrate, and concentrate the filtrate under reduced pressure to a relative density of 1.05g / ml (60°C ) extract, add ethanol until the alcohol content is 70%, let it stand for 24 hours, take the supernatant, recover the ethanol until it has n...

Embodiment 2

[0018] A compound combination medicine for treating asthma, comprising the following components in parts by weight: 20 parts of Shegan, 35 parts of Zhimahuang, 50 parts of Gualou, 20 parts of Scallop (stir-fried), 50 parts of Bombyx mori (stir-fried), and Radix Paeoniae Alba (Fried) 40 parts, 90 parts of Tinglizi, 50 parts of roasted licorice, 50 parts of Dilong, 50 parts of Cnidium, 100 parts of clam shells, 60 parts of bitter almonds, 60 parts of ground maple skin, 100 parts of sea wind rattan, 60 parts of peach kernels 50 parts, Scutellaria baicalensis, altogether sixteen flavor medicines.

[0019] Weigh the above sixteen herbs in parts by weight, add 8 times of water to soak for 30 minutes, decoct for 3 hours, filter, and concentrate the filtrate under reduced pressure to an extract with a relative density of 1.15 g / ml (60°C), add ethanol to The alcohol content is 80%, let it stand for 24 hours, take the supernatant, recover the ethanol until it has no alcohol smell, conce...

Embodiment 3

[0021] A compound combination medicine for treating asthma, comprising the following components in parts by weight: 50 parts of Shegan, 45 parts of Zhimahuang, 100 parts of Gualou, 50 parts of Scallion (stir-fried), 50 parts of Bombyx mori (stir-fried), and Radix Paeoniae Alba (Fried) 60 parts, 100 parts of Tinglizi, 50 parts of roasted licorice, 100 parts of earthworm, 100 parts of cnidium, 100 parts of clam shell, 50 parts of bitter almond, 150 parts of ground maple skin, 150 parts of sea wind rattan, 60 parts of peach kernel 50 parts, Scutellaria baicalensis, altogether sixteen flavor medicines.

[0022] Weigh the above sixteen herbs in parts by weight, add 15 times the amount of water to soak for 45 minutes, decoct 2 times, each time for 1 hour, filter, combine the filtrate, and concentrate the filtrate under reduced pressure to a relative density of 1.10 g / ml (60 ℃), add ethanol until the alcohol content is 60%, let it stand for 24 hours, take the supernatant, recover the...

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PUM

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Abstract

The invention discloses a compound combination medicament for treating asthma and a preparation method thereof. The compound combination medicament comprises the following components in part by weight: 10 to 60 parts of blackberrykiky rhizome, 20 to 50 parts of prepared ephedra herb, 40 to 100 parts of snakegourd fruit, 15 to 60 parts of longstamen onion bulb (fried), 10 to 60 parts of stiff silkworm (fried), 20 to 60 parts of white paeony root (fried), 10 to 100 parts of pepperweed seed, 5 to 70 parts of prepared liquoric root, 15 to 120 parts of earthworm, 10 to 110 parts of common cnidium fruit, 10 to 150 parts of clam shell, 10 to 60 parts of bitter almond kernel, 5 to 160 parts of anisetree bark, 40 to 200 parts of kadsura pepper stem, 10 to 100 parts of peach seed and 10 to 60 parts of baical skullcap root. The compound combination medicament of the invention is used for treating chronic asthma, gurgling with sputum in throat, chest distress, breathing obstruction, shortness of breath, coughing, white phlegm asthma or phlegm-heat type asthma, and has the characteristics of good and thorough curative effect, short treatment course and no side effect and the like. The compound combination medicament can be prepared into mixtures, tablets, capsules, micropills and the like to facilitate carrying and administration.

Description

technical field [0001] The invention relates to a compound combination medicine, in particular to a compound combination medicine for treating bronchial asthma which is made from decoction pieces of traditional Chinese medicines and a preparation method thereof. Background technique [0002] Asthma is a recognized medical problem in the world. So far, there is no radical cure. It is listed by the World Health Organization as one of the four major persistent diseases. There are at least 20 million asthmatics in my country. It is a chronic airway inflammation involving a variety of cells, especially mast cells, eosinophils, and T lymphocytes; in susceptible individuals, this inflammation can cause recurrent symptoms such as wheezing, shortness of breath, chest tightness, and coughing, Occurs mostly at night or in the early morning. Asthma treatment aims to control symptoms as much as possible (including nocturnal symptoms), improve mobility and quality of life, and bring lung...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8962A61P11/06A61K35/56A61K35/64A61K35/618A61K35/62
Inventor 史锁芳刘志辉曹世宏
Owner JIANGSU PROVINCIAL HOSPITAL OF TCM
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