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Compound red yeast capsule

A compound red yeast yeast capsule and red yeast rice technology, applied in capsule delivery, pharmaceutical formulation, food science and other directions, can solve the problems of human body side effects, gastrointestinal reactions, increased liver and kidney burden, etc., achieve good lipid-lowering effect, guarantee Safe and good lipid-lowering effect

Inactive Publication Date: 2011-01-12
晨光生物科技集团天津有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] Lovastatin products currently on the market have some deficiencies: for example, the raw material used in some products is chemically synthesized lovastatin, which has certain side effects on the human body, has gastrointestinal reactions, and easily increases the burden on the liver and kidneys. In addition, the market Some red yeast rice products on the Internet existed before the national standards came out, so the daily consumption exceeds the safe consumption range stipulated by the state
[0008] At present, there is no compound preparation with red yeast rice, ginkgo biloba extract, and eucommia leaf extract as ingredients.

Method used

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  • Compound red yeast capsule
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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] A compound red yeast rice capsule is prepared by the following method:

[0021] Content preparation: Take 66kg of red yeast rice powder, 11.4kg of ginkgo leaf extract, and 22.6kg of eucommia leaf extract. After mixing the above three fine powders in a mixer, fill them into No. 0 empty capsules, each capsule Pack 0.3g.

[0022] The lovastatin in the red yeast rice is 2.5% of the red yeast rice powder obtained through natural fermentation.

[0023] The ginkgo biloba extract meets the regulations of the first part of the 2010 edition of the People's Republic of China Pharmacopoeia.

[0024] The eucommia ulmoides leaf extract is a refined eucommia ulmoides leaf extract powder with a chlorogenic acid content of 40%.

[0025] The total weight of the contents is 100kg, which can be made into 333,333 capsules, each capsule is 300mg, the main functional ingredient lovastatin content is 1.65%, and each capsule contains 4.95mg pure lovastatin.

Embodiment 2

[0027] A compound red yeast rice capsule is prepared by the following method:

[0028] Content preparation: Take 30kg of red yeast rice powder, 12kg of ginkgo leaf extract, 58kg of eucommia leaf extract, mix the above three fine powders evenly in a mixer, and fill them in No. 0 empty capsules, each capsule contains 0.3 g.

[0029] The lovastatin content in the red yeast rice is 4% of the red yeast rice powder obtained by pure natural fermentation.

[0030] The ginkgo biloba extract meets the regulations of the first part of the 2010 edition of the People's Republic of China Pharmacopoeia.

[0031] The eucommia leaf extract is a refined eucommia leaf extract powder with a chlorogenic acid content of 20%.

[0032] The total weight of the contents is 100kg, which can be made into 333,333 capsules, each capsule is 300mg, the main functional ingredient lovastatin content is 1.20%, and each capsule contains 3.60mg pure lovastatin.

Embodiment 3

[0034] A compound red yeast rice capsule is prepared by the following method:

[0035] Content preparation: Take 85kg of red yeast rice powder, 1kg of ginkgo leaf extract, 14kg of eucommia leaf extract, mix the above three fine powders in a mixer, and fill them into No. 0 empty capsules, each capsule contains 0.3 g.

[0036] The red yeast rice is a powder of red yeast rice obtained by fermentation with lovastatin content of 0.5% by mass.

[0037] The ginkgo biloba extract meets the regulations of the first part of the 2010 edition of the People's Republic of China Pharmacopoeia.

[0038] The eucommia leaf extract is a refined eucommia leaf extract powder with a chlorogenic acid content of 50%.

[0039] The total weight of the contents is 100kg, which can be made into 333,333 capsules, each capsule is 300mg, the main functional ingredient lovastatin is 0.425% by mass, and each capsule contains 1.275mg pure lovastatin.

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Abstract

The invention discloses a compound red yeast capsule. 30% to 85% of red yeast, 1% to 12% of ginkgo biloba extract and 3% to 69% of eucommia leaf extract by mass percent form a composition and are filled in an empty capsule, wherein the red yeast is prepared by natural fermentation and the mass percent of lovastatin in the red yeast is 0.5% to 4%. The mass percent of the lovastatin in the raw material of the red yeast in each capsule can meet effective dosage and ensure the safety of the product. The raw material of the red yeast of contents is a naturally fermented product. The acid proportion is more than 70%. Relative to some products having the raw material of chemically synthesized lovastatin in the market, the capsule has the advantages of direct absorption by human bodies and difficult generation of side effects. Proved by a test, relative to a single red yeast product, the compound red yeast capsule of the invention has better lipid lowering effect and can ensure the safety of eaters.

Description

Technical field [0001] The invention relates to the field of health foods, in particular to a compound red yeast rice capsule. Background technique [0002] Red yeast rice is considered by Chinese medicine as an extremely precious health supplement and has good therapeutic effects on certain diseases. According to the theory of traditional Chinese medicine, red yeast rice is sweet and warm, has the effects of lowering blood lipids, lowering low-density lipoprotein cholesterol and preventing cardiovascular and cerebrovascular diseases. Its active ingredients are lovastatin and 5 structural analogs. [0003] The natural lovastatin in red yeast rice is a powerful inhibitor of cholesterol synthase. Its activity is 10,000 times that of cholesterol synthase. It can reduce low-density lipoprotein cholesterol by 20%-60% and effectively lower triglycerides. Elevating the level of high-density lipoprotein, keeping the blood clean, and restoring the normal flow of the blood, it is effective ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/46A61K9/48A23L1/29A61P3/06A23L33/00
Inventor 田洪李娜张卫军
Owner 晨光生物科技集团天津有限公司
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