Compound polyhexamethylene guanidine complexing iodine disinfector and preparation method thereof

Abstract

The invention relates to a compound polyhexamethylene guanidine complexing iodine disinfector and a preparation method thereof. The compound polyhexamethylene guanidine complexing iodine disinfector comprises the following components in percentage by mass: 0.1-0.5 percent of polyhexamethylene guanidine, 0.5-5 percent of PVP-I (polyvinylpyrrolidone iodine), 30-70 percent of ethanol, 0.1-1 percent of non-ionic surface active agent, 0.5-3 percent of skin-protecting agent, 0.05-0.2 percent of citric acid and the balance of water. The preparation method of the compound polyhexamethylene guanidine complexing iodine disinfector comprises the following steps of: adding polyvinylpyrrolidone iodine into the water according to the content and the components, and stirring the mixture to dissolve; sequentially adding the non-ionic surface active agent, the skin-protecting agent and the citric acid, and stirring the mixture to dissolve; adding and stirring ethanol to the mixture uniformly; and adding and stirring polyhexamethylene guanidine to the mixture uniformly to obtain the compound polyhexamethylene guanidine complexing iodine disinfector. The compound polyhexamethylene guanidine complexing iodine disinfector has the characteristics of stable characteristics, quick and lasting sterilization function, low simulation to skins, quick drying and convenient use.

Description

technical field [0001] The invention relates to a disinfectant, in particular to a compound polyhexamethyleneguanidine complexed iodine disinfectant and a preparation method thereof. Background technique [0002] Polyhexamethyleneguanidine is a broad-spectrum, quick-acting fungicide, which acts on the cell wall and cytoplasmic membrane system of bacteria and fungi, combines with fatty acids in the cell membrane phospholipids, quickly penetrates their cytoplasmic membranes, and breaks through the pathogenic cells. The core, so that the living matter in the pathogenic bacteria outflows, so as to achieve the bactericidal effect. Used in combination with other fungicides, it can exert an excellent disinfection effect. Because polyhexamethyleneguanidine has a non-specific mode of killing bacteria, it is very unlikely that bacteria will develop resistance to it. [0003] Iodine is a commonly used disinfectant that destroys the outer layer of bacteria by iodination. Polyvinylpyr...

AI Technical Summary

Problems solved by technology

Polyvinylpyrrolidone-iodine (PVP-I) is a complex formed between iodine and polymer compound polyvinylpyrrolidone, which can continuously release free iodine and exert long-acting effects, but has the disadvantage of slow onset

[0004] Ethanol is a commonly used disinfectant. Its bactericidal effect is due to their ability to denature proteins. It is characterized by rapid action, but it is easy to produce drug-resistant bacteria