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Method for quickly removing metronidazole by utilizing nanoscale zero-valent iron and application thereof

A nano-zero-valent iron and metronidazole technology, applied in the field of environmental chemistry, can solve problems such as expensive radiation sources, large infrastructure investment, and difficult recovery of photocatalysts, achieving mild reaction conditions, simple reaction processes, and low equipment requirements Effect

Inactive Publication Date: 2010-10-13
SOUTH CHINA NORMAL UNIVERSITY
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  • Abstract
  • Description
  • Claims
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Problems solved by technology

[0004] At present, the removal methods of metronidazole mainly include physical adsorption method, photodegradation method, biological method and ray irradiation method, but these methods all have shortcomings: physical adsorption method simply enriches and separates the pollutants in wastewater, only The pollutants are transferred, but the pollutants are not degraded and removed, and the effect is not ideal; the photodegradation method needs light as the catalytic power, and photocatalysts such as TiO 2 There are problems such as difficulty in recycling, which is uneconomical; biological treatment takes a long time and the effect is slow; ray irradiation is a new treatment technology, but this technology requires a large investment in infrastructure, and the radiation source used is also relatively expensive, which is uneconomical and ineffective. actual

Method used

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  • Method for quickly removing metronidazole by utilizing nanoscale zero-valent iron and application thereof
  • Method for quickly removing metronidazole by utilizing nanoscale zero-valent iron and application thereof
  • Method for quickly removing metronidazole by utilizing nanoscale zero-valent iron and application thereof

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Embodiment 1

[0032] (1) Preparation of nano-zero-valent iron: The preparation of nano-zero-valent iron adopts a liquid phase chemical reduction method, and uses polyvinylpyrrolidone as a dispersant, and then uses FeSO 4 ·7H 2 O and excess NaBH 4 The zero-valent iron particles prepared by reaction and reduction have good dispersion effect and are not prone to agglomeration. Specific steps: Deionized water for solution preparation is first charged with N 2 30min to remove the dissolved oxygen in the solution, and then used to prepare a 30% ethanol aqueous solution. Weigh 0.55g FeSO 4 ·7H 2 O is dissolved in 100ml of 30% ethanol aqueous solution to prepare 0.02mol / L FeSO 4 ·7H 2 O aqueous solution, and then add polyvinylpyrrolidone (0.11g) at a mass ratio of 1:1 (iron content in iron salt: PVP K-30, m / m), and mechanically stir to make it fully mixed and dissolved. Weigh 0.25g NaBH 4 Dissolve it with 100ml of 30% ethanol aqueous solution to prepare 0.06mol / L NaBH 4 Aqueous solution. Under the ...

Embodiment 2

[0037] (1) Preparation of nano-zero-valent iron: the preparation method of nano-zero-valent iron in this embodiment is the same as that of the above-mentioned embodiment 1(1).

[0038] (2) Nano-zero-valent iron treatment of metronidazole under different initial pH conditions: adjust the initial pH of the metronidazole solution with an initial concentration of 80 mg / L with HCl or NaOH, so that the initial pH of the solution is 3-9 . Take 300mL of each concentration, then add 30mg of nano-zero-valent iron, and react under electric stirring at 180rpm at different time intervals. Take 2-3mL water samples from the bottle and filter through a 0.45μm filter membrane before using high performance liquid chromatography. Determine the concentration of residual metronidazole antibiotic. The result is Figure 4 It is shown that even under the condition that the pH value of the system changes greatly, a higher removal rate can still be achieved, all above 85%, and the removal efficiency is h...

Embodiment 3

[0040] (1) Preparation of nano-zero-valent iron: the preparation method of nano-zero-valent iron in this embodiment is the same as that of the above-mentioned embodiment 1(1).

[0041] (2) Nano zero-valent iron and commercial iron powder (>99%, 3m 2 / g, the average particle size is 69μm, purchased from Tianjin Komeo Chemical Reagent Co., Ltd.) Act on metronidazole: 300ml of metronidazole solution with an initial concentration of 80mg / L (without adjusting the initial pH of the solution) , Its initial pH = 5.60) was put into nano zero-valent iron and commercial iron powder, so that the dosage of both are 0.1g / L. The reaction was carried out under electric stirring at a rotation speed of 180 rpm, and 2-3 mL of water samples were taken from the bottle at different intervals and filtered through a 0.45 μm filter membrane. The concentration of the residual metronidazole antibiotic was determined by high performance liquid chromatography. The response result is like Figure 5 As shown ...

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Abstract

The invention discloses a method for quickly removing metronidazole by utilizing nanoscale zero-valent iron and application thereof. The method comprises the following steps: adjusting the pH value of a metronidazole-containing solution to be 3-9, adding nanoscale zero-valent iron and stirring. The invention first discovers that the nanoscale zero-valent iron can quickly and efficiently remove metronidazole, and the higher removal efficiency under the condition of larger change in pH value can reach more than 85%. The invention has simple reaction process, convenient operation, low requirements for equipment and low operating cost. The invention does not need add other chemical reagents, does not produce secondary pollution, and is efficient and environmentally friendly. The invention can be widely used in the fields of environmental pollution control and environmental remediation, and has good market prospects.

Description

Technical field [0001] The invention belongs to the field of environmental chemistry, and particularly relates to a method for rapidly removing metronidazole by using nano zero-valent iron and its application. Background technique [0002] Metronidazole (MNZ), commonly known as metronidazole, is one of the commonly used nitroimidazole antibiotics in clinical practice. It has antibacterial and anti-inflammatory effects. It is widely used in China, Europe and the United States, and is mainly used to treat anaerobic bacteria and protozoa. Such as infections caused by Trichomonas vaginalis and Giardia. The production capacity and output of metronidazole raw materials in my country is relatively large. There are more than 120 domestic manufacturers of metronidazole tablets. The output in 2000 was 2.793 billion tablets. In 2001, the output was 11% compared with the previous year, and the output was 2.488 billion tablets. It accounts for 0.4% of the total number of tablets in my country...

Claims

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Application Information

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IPC IPC(8): C02F1/58C02F1/70C02F101/38
Inventor 方战强陈金红邱心泓丘秀琪黄华坚
Owner SOUTH CHINA NORMAL UNIVERSITY
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