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Bioactive facial mask and preparation method therefore

A bioactive and bioactive factor technology, applied in the field of daily cosmetics, can solve the problems of destroying the natural silk fibroin structure, losing the biological efficacy of silk fibroin, and not having bioactive functions, etc., achieving process maturity and accelerating skin tissue repair. , the effect of good biosafety

Inactive Publication Date: 2010-09-15
马兆成
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In addition, some silk protein masks on the market are made of acid-base treatment and degraded silk fibroin combined with non-woven fabrics, which destroys the structure of natural silk fibroin and loses the biological efficacy of silk fibroin.
The Chinese patent "Preparation Method of Soluble-Highly Elastic Silk Fibroin Film" with the approval announcement number CN101234212 uses silk fibroin to dry directly to form a film, but this film has a simple structure and does not have biological activity functions

Method used

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  • Bioactive facial mask and preparation method therefore
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  • Bioactive facial mask and preparation method therefore

Examples

Experimental program
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Effect test

Embodiment 1

[0023] Embodiment 1: be used for the bioactive mask of face liposuction water-retaining nutrition

[0024] Weigh 8g of silk fibroin with a balance, add it to 20ml of sterilized water, stir and dissolve for 1 hour, and after degassing for 1 hour, pour it into a mold and cast it to form a film. In this example, a plastic mold is used, and it is volatilized at room temperature. After 2 days, vacuum-dry at 60° C. for 12 hours to obtain a scaffold layer. Separately take silk fibroin and dissolve it in deionized water to form a silk fibroin aqueous solution with a concentration of 30wt%, and then apply it evenly on the surface of the above-mentioned support layer to form a silk fibroin water layer with a thickness of 2 mm, and quickly put it Freeze in a -80°C refrigerator for 10 hours to fix the silk fibroin aqueous layer on the support layer, and then put it into a vacuum freeze dryer to dry at -60°C for 10 hours to obtain a porous nano active layer. Add natural plant extract (suc...

Embodiment 2

[0025] Example 2: Bioactive Mask for Facial Skin Tissue Regeneration

[0026] Weigh 8g of silk fibroin with a balance, add it to 20ml of sterilized water, stir and dissolve for 1 hour, and after degassing for 1 hour, pour it into a mold and cast it to form a film. In this example, a plastic mold is used, and it is volatilized at room temperature. After 2 days, vacuum-dry at 60° C. for 12 hours to obtain a scaffold layer. Adopt electrospinning method, carry out spray spinning on above-mentioned support layer with the silk fibroin protein aqueous solution of concentration 20wt% according to conventional conditions, obtain the silk fibroin protein aquifer layer that thickness is 3mm, put it into -80 ℃ refrigerator to freeze rapidly 5 hours, the silk fibroin aqueous layer was fixed on the support layer, and then placed in a vacuum freeze dryer at -30° C. for 15 hours to obtain a porous nano active layer. The epidermal growth factor is added to the silk fibroin aqueous solution wi...

Embodiment 3

[0027] Example 3: Bioactive Mask for Facial Skin Repair

[0028] Weigh 8g of silk fibroin with a balance, add it to 20ml of sterilized water, stir and dissolve for 1 hour, and after degassing for 1 hour, pour it into a mold and cast it to form a film. In this example, a plastic mold is used, and it is volatilized at room temperature. After 2 days, vacuum-dry at 60° C. for 12 hours to obtain a scaffold layer. Using the electrospinning method, according to the conventional conditions, the silk fibroin aqueous solution with a concentration of 25wt% is sprayed on the above-mentioned support layer to obtain a silk fibroin water layer with a thickness of 5 mm, which is quickly put into a -80 ° C refrigerator for 7 hours. The silk fibroin aqueous layer is fixed on the support layer, and then placed in a vacuum freeze dryer for drying at -60° C. for 10 hours to obtain a porous nano active layer. The epidermal cell repair factor is added to the silk fibroin aqueous solution with a con...

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Abstract

The invention discloses a bioactive facial mask and a preparation method therefore. The facial mask is of a composite structure, and comprises a bracket layer and a porous nano active layer which is adhered on the bracket layer; and silk fibroin which is mixed with a bioactive factor, a medicament factor or the mixture of the two is adsorbed on the active layer. The preparation method comprises the following steps of: preparing the silk fibroin into the bracket layer by dissolving-film making procedures; coasting or spraying aqueous solution of silk fibroin on the surface of the bracket layer, quickly freezing the bracket layer at low temperature and performing freeze drying on the bracket layer under vacuum to obtain the porous nano active layer; and then soaking the porous nano active layer in the solution of silk fibroin mixed with the bioactive factor, the medicament factor or the mixture of the two, demoulding and packaging the porous nano active layer in the wet state to obtain the bioactive facial mask. The bioactive facial mask has the advantages of wide range of application people, natural source, green and safety, no chemical additives, no anaphylactic reaction, high biological safety and biological activity, simple preparation method, mature process and easy control.

Description

technical field [0001] The invention relates to a bioactive facial mask and a preparation method thereof, in particular to a bioactive facial mask capable of anti-wrinkle and assisting the repair and regeneration of epidermal tissue and a preparation method thereof, belonging to the field of daily cosmetics. Background technique [0002] Silk fibroin is a high-purity natural protein extracted from natural silk. It is composed of 18 kinds of amino acids such as glycine, alanine, and tyrosine, which are similar to the protein composition of human skin. Silk fibroin is used as a mask material, because of its good air permeability, water retention and biocompatibility, combined with bioactive factors, it can enhance skin metabolism, assist tissue repair and regeneration, anti-wrinkle, delay skin aging, and provide high-end beauty products. Product development provides a new and efficient approach. [0003] The facial masks currently reported in the literature mainly include the...

Claims

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Application Information

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IPC IPC(8): A61K8/02A61K8/64A61K8/97A61Q19/00A61P29/00A61P37/08
Inventor 马兆成张玉峰
Owner 马兆成
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