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Gynostemma pellet preparation for preventing subclinical mastitis and preparation method thereof

A technique for recessive mastitis and Gynostemma pentaphyllum, which is applied in the preparation and preparation of Gynostemma pentaphyllum pellets for the prevention and treatment of recessive mastitis in dairy cows. It can solve the problems of ineffective effects, drug residues, and health risks, and achieves non-toxic side effects and stable drug release. , the effect of increasing the number of white blood cells

Inactive Publication Date: 2010-09-08
NORTHEAST AGRICULTURAL UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Most of the existing preventive medicaments or additives are traditional Chinese medicine powders or levamisole hydrochloride, which either have ineffective effects or have drug residues, leaving hidden dangers to people's health.

Method used

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  • Gynostemma pellet preparation for preventing subclinical mastitis and preparation method thereof
  • Gynostemma pellet preparation for preventing subclinical mastitis and preparation method thereof
  • Gynostemma pellet preparation for preventing subclinical mastitis and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0012] Weigh 50 parts of Jiaogulan, 30 parts of starch, 20 parts of dextrin, 7 parts of cellulose acetate and 15002.5 parts of polyethylene glycol by weight. Crush Gynostemma pentaphyllum into fine powder, add 20 times of 80% ethanol, put it in an ultrasonic extraction extractor for ultrasonic extraction at 90°C for 1 hour, extract 3 times in total, combine the filtrate, recover ethanol, and dry in vacuum to obtain Gynostemma pentaphyllum extract powder; Polyethylene glycol 1500 is dissolved in an appropriate amount of ethanol to form a coating solution; the Gynostemma pentaphyllum extract powder, starch, and dextrin are mixed evenly, and 70% ethanol solution is passed through a 20-mesh sieve to make wet granules, and the wet granules are rolled in a coating pan for 10 After -30 minutes, open the cover, heat at 60°C, roll for 1 hour, take out the pellets and dry them in an oven, then put the dried pellets into the coating pot, spray the coating solution, and coat until the coat...

Embodiment 2

[0014] Weigh 20 parts of Jiaogulan, 50 parts of starch, 25 parts of dextrin, 8 parts of cellulose acetate and 15003 parts of polyethylene glycol by weight. Crush Gynostemma pentaphyllum into fine powder, add 20 times of 80% ethanol, put it in an ultrasonic extraction extractor for ultrasonic extraction at 90°C for 1 hour, extract 3 times in total, combine the filtrate, recover ethanol, and dry in vacuum to obtain Gynostemma pentaphyllum extract powder; Polyethylene glycol 1500 is dissolved in an appropriate amount of ethanol to form a coating solution; the Gynostemma pentaphyllum extract powder, starch, and dextrin are mixed evenly, and 70% ethanol solution is passed through a 20-mesh sieve to make wet granules, and the wet granules are rolled in a coating pan for 10 After -30 minutes, open the cover, heat at 60°C, roll for 1 hour, take out the pellets and dry them in an oven, then put the dried pellets into the coating pot, spray the coating solution, and coat until the coatin...

Embodiment 3

[0016] Weigh 40 parts of Jiaogulan, 30 parts of starch, 30 parts of dextrin, 4 parts of cellulose acetate and 15001.5 parts of polyethylene glycol by weight. Crush Gynostemma pentaphyllum into fine powder, add 20 times of 80% ethanol, put it in an ultrasonic extraction extractor for ultrasonic extraction at 90°C for 1 hour, extract 3 times in total, combine the filtrate, recover ethanol, and dry in vacuum to obtain Gynostemma pentaphyllum extract powder; Polyethylene glycol 1500 is dissolved in an appropriate amount of ethanol to form a coating solution; the Gynostemma pentaphyllum extract powder, starch, and dextrin are mixed evenly, and 70% ethanol solution is passed through a 20-mesh sieve to make wet granules, and the wet granules are rolled in a coating pan for 10 After -30 minutes, open the cover, heat at 60°C, roll for 1 hour, take out the pellets and dry them in an oven, then put the dried pellets into the coating pot, spray the coating solution, and coat until the coat...

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Abstract

The invention relates to a gynostemma pellet preparation for preventing subclinical mastitis and a preparation method thereof, which belong to the field of veterinary medicine; and the preparation is prepared from gynostemma, starch, dextrin, cellulose acetate and polyethylene glycol 1500 with different weights, improves immunity by increasing the number of white blood cells, enhancing T cells and promoting the production of macrophages, prevents and cures mastitis, and has the advantages of high curing effect, no toxin, no side effect and no residue.

Description

Technical field [0001] The invention belongs to the technology of veterinary medicine, and mainly relates to a Gynostemma pentaphyllum pellet preparation and a preparation method for preventing and treating subclinical mastitis of cows. Background technique [0002] Cow mastitis, also known as cow mastitis, is a common and frequently-occurring disease in cows. Despite years of research, it remains one of the most costly diseases in dairy farming. The occurrence of mastitis is directly related to pathogenic microorganisms and the environment, which seriously hinders the development of dairy farming and causes great losses to farmers. [0003] The current treatment methods are generally based on oral administration, infusion, and injection of antibiotics. Although the treatment is effective, there are indeed residual problems. According to the regulations of the Ministry of Agriculture, different antibiotics have different milk abandonment periods. During the milk abandonment...

Claims

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Application Information

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IPC IPC(8): A61K36/424A61K9/16A61K47/38A61P15/14
Inventor 岳奎忠张翔徐志辉
Owner NORTHEAST AGRICULTURAL UNIVERSITY
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