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Preparation method of Chinese medicinal composition for treating urinary system infection

A technique for urinary system infection and composition is applied in the field of preparation of traditional Chinese medicine compositions, and can solve the problems of loss of effective components of medicines, reduction of drug efficacy, poor taste and the like

Active Publication Date: 2012-05-23
HUNAN JIUDIAN PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The method of taking the decoction is decoction, which is extremely inconvenient to use, and the taste is poor and troublesome to take, which brings great inconvenience to the majority of patients. In addition, during the decoction process, the active ingredients of the medicine are easily lost and the efficacy of the medicine is reduced, which is not conducive to patient recovery

Method used

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  • Preparation method of Chinese medicinal composition for treating urinary system infection
  • Preparation method of Chinese medicinal composition for treating urinary system infection
  • Preparation method of Chinese medicinal composition for treating urinary system infection

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0051] Embodiment 1 Chinese medicine composition capsule preparation of the present invention

[0052] Grind 600g of turmeric into coarse powder, add 14 times the amount of water to extract the volatile oil by steam distillation for 8 hours, and use β-cyclodextrin to clathrate the volatile oil. The mixing time is 2 hours, and the clathrate is used for later use; Phellodendron 360g, Gardenia 480g and Tribulus terrestris 600g are processed into coarse powder, and 8 times the amount of 60% ethanol is refluxed twice, the first time is 2 hours, and the second time is 1.5 hours. The extracts are filtered and combined, the combined filtrate is recovered with ethanol, the filtrate is concentrated to a concentrated solution with a relative density of 1.30-1.35 (60°C), and then vacuum-dried at 65°C to obtain a dry extract, which is crushed and sieved, and added to the β-cyclopaste The finely encapsulated turmeric volatile oil is mixed evenly, and suitable pharmaceutical excipients are a...

Embodiment 2

[0053] Embodiment 2 pharmaceutical tablet preparation of the present invention

[0054] Turmeric 480g is pulverized into coarse powder, extracts volatile oil with supercritical extraction, extraction pressure 30MPa, extraction temperature 50 ℃, static extraction 3 hours, dynamic extraction 3 hours, dehydrated alcohol is as entrainer, consumption 27% (ratio with material, with supercritical CO 2 The fluid is pumped into the extractor synchronously), CO 2 The flow rate is 3.0L / min; the volatile oil is clathrated with β-cyclodextrin, the amount of β-cyclodextrin and volatile oil is 5:1, the clathrate temperature is 75°C, the clathrate time is 2 hours, and the clathrate is ready for use; Phellodendron 480g , Gardenia 360g, Tribulus terrestris 480g shamisen is pulverized into coarse powder, adds 50% ethanol 9 times amount and extracts 3 times, each 1.5 hours, after extracting solution is filtered, merge filtrate, 65 ℃ of vacuum drying, obtain dry extractum. The dry extract is cru...

Embodiment 3

[0055] Embodiment 3 preparation of pharmaceutical granules of the present invention

[0056] Grind turmeric 720g into a coarse powder, add 12 times the amount of water to extract the volatile oil by steam distillation for 7 hours, and absorb the volatile oil with calcium hydrogen phosphate for later use; 240g Cortex Phellodendri, 600g Gardenia, and 480g Tribulus tribulus are crushed into coarse powder, add 8 times the amount of 60% ethanol Reflux extraction twice, 2 hours for the first time, 0.5 hours for the second time, filter the extract, combine the filtrates, and vacuum-dry at 65°C to obtain a dry extract. The dry extract is pulverized into fine powder, added with calcium hydrogen phosphate that has absorbed the volatile oil of turmeric, mixed evenly, added suitable auxiliary materials to granulate, granulated, and prepared into 1000 packs of granules.

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Abstract

The invention provides a novel preparation method of a Chinese medicinal composition for treating urinary system infection, and particularly relates to the novel preparation method of the Chinese medicinal composition prepared from the following raw material medicaments: curcuma longa, gardenia jasminoides, puncturevine caltrop fruit and the like. The method has a simple process, is suitable for industrialized production, improves medicinal effect and greatly reduces production cost.

Description

technical field [0001] The invention relates to a preparation method of a traditional Chinese medicine composition for treating urinary system infection. Background technique [0002] The Xieriga Siwei Decoction Powder in the Mongolian medicine sub-volume (1998) of the "Drug Standards of the Ministry of Health of the People's Republic of China" is used by ethnic minorities. Urgency, blood in urine, bladder tingling. The method of taking the decoction is decoction, which is extremely inconvenient to use, and the taste is poor and troublesome to take, which brings great inconvenience to the patients. In addition, during the decoction process, the active ingredients of the medicine are easily lost, and the efficacy of the medicine is reduced, which is not conducive to Patient's recovery. The inventor carried out secondary development on it, extracting various Chinese herbal medicines in this prescription to prepare modern Chinese medicine, see the invention patent with the pa...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/9066A61K9/16A61K9/20A61K9/48A61P13/00A61P31/00
Inventor 朱志宏卜振军杨静
Owner HUNAN JIUDIAN PHARMA
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