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Preparation process of galangal and rhizoma cyperi liquid capsule

A preparation process and technology of liquid capsules, which are applied in the directions of capsule delivery, medical preparations containing active ingredients, plant raw materials, etc., can solve the problems of incomplete extraction of active ingredients, complicated extraction methods, destruction of active ingredients, etc. Small, safe and reliable to take, the effect of active ingredients is improved

Inactive Publication Date: 2012-04-18
TIANJIN PACIFIC PHARMA
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  • Abstract
  • Description
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AI Technical Summary

Problems solved by technology

When preparing Liangfu, it is necessary to extract the active ingredients in Galangal and Rhizoma Cyperi. The existing extraction methods usually use high-temperature solvent extraction. The problems in this method are: (1) The extraction method is complicated and the active ingredients are not extracted completely 1. High-temperature extraction destroys the active ingredients; (2) Due to the use of a large amount of solvents, concentration treatment is required to cause solvent residues; (3) The existing Liangfu is usually a pill, which has the disadvantages of large dosage and inconvenience.

Method used

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Embodiment Construction

[0021] The embodiments of the present invention are described in further detail below.

[0022] A preparation process of Liangfu liquid capsule, comprising the following steps:

[0023] (1), 3000 grams of galangal and 3000 grams of Rhizoma Cyperi are pulverized into coarse powder respectively.

[0024] (2) Using carbon dioxide supercritical extraction method to extract galangal and obtain galanga extract, the extraction conditions are as follows: extraction temperature is 38-42°C, extraction pressure is 10-20Mpa, analysis temperature is 33-39°C, The analysis pressure is 6-9Mpa. In this embodiment, the best extraction conditions are adopted: the extraction temperature is 40°C, the extraction pressure is 15Mpa, the analysis temperature is 36°C, and the analysis pressure is 8Mpa.

[0025] (3) Using carbon dioxide supercritical extraction method to extract Rhizoma Cyperi and obtain Rhizoma Cyperi extract, the extraction conditions are as follows: extraction temperature is 32-35°C...

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Abstract

The invention relates to a preparation process of a galangal and rhizoma cyperi liquid capsule, which comprises the following processing steps: (1) respectively pulverizing galangal and rhizoma cyperi based on the weight ratio of 1:1 into coarse powder; (2) extracting the galangal by a carbon dioxide supercritical extraction method to obtain the extract of the galangal; (3) extracting the rhizomacyperi by a carbon dioxide supercritical extraction method to obtain the extract of the rhizoma cyperi; (4) mixing the galangal extract and the rhizoma cyperi extract and dehydrating to obtain the galangal and rhizoma cyperi extract; (5) adding vegetable oil and tween 80 to the galangal and rhizoma cyperi extract and mixing evenly to obtain galangal and rhizoma cyperi liquid; and (6) filling the galangal and rhizoma cyperi liquid and sealing to obtain the galangal and rhizoma cyperi liquid capsule. The invention respectively adopts different extraction conditions for carrying out carbon dioxide supercritical extraction on the effective components of the galangal and the rhizoma cyperi, reserves the effective components in the raw materials and improves the extraction rate, and the prepared galangal and rhizoma cyperi liquid capsule has the characteristics of safety, reliability, convenient taking, small dose, convenient carrying and the like.

Description

technical field [0001] The invention relates to a preparation process of traditional Chinese medicine, in particular to a preparation process of Liangfu liquid capsule. Background technique [0002] As a Chinese patent medicine, Liangfu has the effect of warming the stomach and regulating qi, and can be widely used for symptoms such as cold stagnation, stagnation of qi, abdominal pain, acid regurgitation, and fullness of the chest and abdomen. Liangfu mainly contains two traditional Chinese medicine ingredients: galangal and Cyperus cyperi. The main components of galangal are pinene, galangol and various flavonoids, which have antibacterial effects; Cyperol and β-cyperol have the effects of analgesia, uterine contraction inhibition and antibacterial effects, so Liangfu can treat chronic gastritis, gastric and duodenal ulcers, chronic hepatitis and other diseases caused by stagnation of liver qi caused by cold condensation. When preparing Liangfu, it is necessary to extract ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/9062A61K9/48A61P1/04A61P1/16
Inventor 宋德成冯红王爱明朱丽宁德科
Owner TIANJIN PACIFIC PHARMA
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