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Preparation of compound extract of anemarrhena, astragalus and bitter gourd and use thereof

A technology of extract and Radix Astragali, which is applied in the field of preparation of Zhimu, Radix Astragali, Bitter Gourd three-flavor Chinese medicine compound and its extract, which can solve problems such as improving lipid metabolism

Inactive Publication Date: 2010-06-16
SHANGHAI NORMAL UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

At the same time, the document JP2003-104812A also shows that bitter melon saponin still has the effect of improving lipid metabolism.

Method used

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  • Preparation of compound extract of anemarrhena, astragalus and bitter gourd and use thereof
  • Preparation of compound extract of anemarrhena, astragalus and bitter gourd and use thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment

[0018] The proportioning of each component of Examples 1-4 is shown in Table 1.

[0019] Each component ratio of table 1 (weight ratio)

[0020]

[0021] 1. Extraction method

[0022] Add 8-10 times the volume of water to decoct the coarse powder of Anemarrhena, Astragalus, and bitter melon medicinal slices for 3 times, each time for 1.5-2 hours, and filter; combine the filtrates, concentrate under reduced pressure, add 3 times the volume of 95% alcohol to precipitate, Filtration; the filtrate was concentrated under reduced pressure, and the concentrated solution was again precipitated with 95% alcohol to obtain an extract, which was dried under reduced pressure and pulverized.

[0023] 2. Extraction method of total saponins of Anemarrhena, Radix Astragali, and Bitter Gourd

[0024] Add 8-10 times the volume of water to decoct the coarse powder of Anemarrhena, Astragalus, and bitter melon medicinal slices for 3 times, each time for 1.5-2 hours, and filter; combine the fil...

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PUM

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Abstract

The invention relates to a preparation of a compound extract of anemarrhena, astragalus and bitter gourd and use thereof. The weight ratio of the anemarrhena to astragalus to bitter gourd is 2-4:1-2:1; and the three types of Chinese medicaments are mixed and then processed into an extract or the three types of Chinese medicaments are processed into an extract respectively and then mixed to obtain the extract, and the extract can be made into oral liquid, tablets, capsules or injections. The compound extract of anemarrhena, astragalus and bitter gourd possesses an activity of inhibiting the alpha-glucosidase, and can be used for reducing postprandial glycemia, preventing and treating diabetes and complications of diabetes, and the like.

Description

technical field [0001] The invention relates to the technical field of medicines, in particular to the preparation and application of an anemarrhena, astragalus and bitter gourd three-flavor traditional Chinese medicine compound and an extract thereof. Background technique [0002] Anemarrhena is a plant of Liliaceae, bitter in taste and cold in nature. Go into lung, stomach, kidney channel. It has the functions of clearing away heat and purging fire, nourishing yin and moistening dryness. Cure mainly dysphoria, quench one's thirst. Pharmacological studies have shown that Anemarrhena has antipyretic, hypoglycemic, choleretic, and anti-platelet aggregation effects. Documents CN1679866A, CN1943705A, CN100366588C, and US4518591 show that the saponins and mangiferins in Anemarrhena have hypoglycemic effects. Yuye Decoction, Baihu Ginseng Decoction, Tangkeqing, Lin Brand Diabetes Capsules, Tangxuening and other decoctions or prescriptions for treating diabetes are often used ...

Claims

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Application Information

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IPC IPC(8): A61K36/8964A61P3/10
Inventor 宋纯清叶晓平茅仁刚
Owner SHANGHAI NORMAL UNIVERSITY
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