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Process for preparing targeting fat-reducing calcium-supplying oral liquid enriched with lecithin-calcium acetate coupled material by lipidosome biotechnology

A biotechnology, lecithin technology, applied in the field of lipid-lowering and calcium-supplementing oral liquid, can solve the problems that the effect of functional ingredients cannot be maximized, the dosage of medical and health care has no standard, and it is not suitable for people with stomach problems, so as to protect liver cells and restore brain. Cell memory function, effect of preventing vascular intima damage

Inactive Publication Date: 2010-05-05
尚诚德 +2
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  • Application Information

AI Technical Summary

Problems solved by technology

[0006] 1. The taste is not good, especially the fishy smell released by the ineffective ingredient egg white is unacceptable to many people
[0007] 2. Lack of disinfection and sterilization measures, can not be stored for a long time, easy to corrupt and deteriorate the effect, and even endanger the health and safety of patients
[0008] 3. The formula ratio is not scientific enough, and the effect of functional ingredients cannot be maximized
[0009] 4. Excessive acidity can easily irritate the stomach and intestines, so it is not suitable for people with stomach problems
[0010] 5. Lack of standard dosage, no standard for medical and healthcare dosage

Method used

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  • Process for preparing targeting fat-reducing calcium-supplying oral liquid enriched with lecithin-calcium acetate coupled material by lipidosome biotechnology
  • Process for preparing targeting fat-reducing calcium-supplying oral liquid enriched with lecithin-calcium acetate coupled material by lipidosome biotechnology
  • Process for preparing targeting fat-reducing calcium-supplying oral liquid enriched with lecithin-calcium acetate coupled material by lipidosome biotechnology

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Embodiment Construction

[0049] 1. Scale up the production of crude phospholipids according to the following proportions: Stir one egg yolk with 40ml of acetone, then centrifuge and discard the supernatant. Use 40ml of chloroform-methanol in a volume ratio of 2:1 to extract the acetone-insoluble matter, protect the extract with nitrogen, concentrate under reduced pressure on a 40°C water bath to nearly dryness, add the resulting concentrate to 100ml of acetone to precipitate phospholipids, and pour it out Acetone, and then dry under reduced pressure at 20-40°C to obtain crude phospholipids whose main component is lecithin. Acetone and chloroform-methanol can be recycled and used repeatedly.

[0050] 2. Add water to the extracted crude lecithin according to the mass ratio of 1:10, use mechanical dispersion or other methods, or directly mix and soak two volumes of vinegar with acetic acid content ≥ 9g / 100ml and one volume of fresh egg yolk for 24 hours to make lecithin For multilayered liposomes, the pr...

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Abstract

The invention discloses a process for preparing targeting fat-reducing calcium-supplying oral liquid enriched with lecithin calcium acetate coupled material by lipidosome biotechnology, which is characterized in that calcium acetate and lecithin lipidosome are coupled together by using the vector function of the lipidosome to prepare the targeting fat-reducing calcium-supplying oral liquid. The process is to couple and encapsulate the lecithin and the calcium acetate which are functional compositions of vinegar-egg juice to form a biological coupled material by using the modern lipidosome biotechnology on the basis of understanding the hygiogenesis of treating diseases by using folk recipe vinegar-egg juice, thereby improving the absorption rate of human body, reinforcing the compound fat-reducing and calcium-supplying functions of lecithin and calcium acetate. The oral liquid can be developed into a medical health-care oral liquid product to ensure that the coupled material has more prominent targeting characteristics and more obvious medical health-care effect.

Description

technical field [0001] The invention relates to a preparation process of an oral liquid for reducing lipid and calcium supplementation with targeting function, specifically a method of encapsulating lecithin and calcium acetate by using liposome biotechnology and relying on the form of oral liquid to strengthen lecithin The preparation process of health care products with calcium acetate compound lipid-lowering calcium supplement and targeted function. Background technique [0002] With the continuous improvement of living standards, the blood lipid level of the crowd increases year by year. About 30-40% of the people suffer from abnormal blood lipid metabolism that exceeds the borderline standard in various degrees, that is, hyperlipidemia. Hyperlipidemia is the main factor causing human atherosclerotic diseases, which can easily lead to hypertension, diabetes, coronary heart disease, cerebral infarction and peripheral vascular embolism. These atherosclerotic diseases hav...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/00A61K31/685A61P3/02A61P3/06A61K31/19
Inventor 尚诚德姜家勇李辉
Owner 尚诚德
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