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Preparation method and anti-obesic application of ginsenoside

A technology of ginseng stems and leaves, obesity, applied to the preparation process of ginseng stems and leaves saponins and its application in the field of pharmacy

Inactive Publication Date: 2009-10-07
JILIN AGRICULTURAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Ginseng stems and leaves mainly contain chemical components such as ginsenosides, polysaccharides, amino acids, proteins, and volatile oils, and the amount of ginsenosides contained in ginseng stems and leaves is higher than that of ginseng taproot. There is no report on the anti-obesity effect of ginseng stems and leaves saponins

Method used

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  • Preparation method and anti-obesic application of ginsenoside
  • Preparation method and anti-obesic application of ginsenoside
  • Preparation method and anti-obesic application of ginsenoside

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0068] Take 1000 g of ginseng stem and leaf coarse powder (40 mesh), add 5 to 10 times the amount of 0 to 40% ethanol aqueous solution, soak for 6 to 12 hours, reflux and extract 3 times, each time for 2 hours, filter, combine the filtrates, and recover the ethanol under reduced pressure. Vacuum dried to obtain 200 g of stem and leaf extract.

Embodiment 2

[0070] Take 1000g of platycodon root, add 5-10 times the amount of 0-40% ethanol aqueous solution, soak for 6-12 hours, ultrasonically extract 3 times, 30 minutes each time, filter, combine the filtrates, recover ethanol under reduced pressure, and vacuum-dry to obtain platycodon grandiflorum extract 250g.

Embodiment 3

[0072] Take 20g of ginseng stem and leaf extract, dissolve it with an appropriate amount of water, apply D101 macroporous resin to the aqueous solution, and elute with water and 40-80% ethanol in turn, collect the ethanol solution, concentrate under reduced pressure, and dry in vacuo to obtain 7g, in which the ginsenoside content is 15% ~35%.

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Abstract

The invention provides a preparation method of ginsenoside, which is suitable for industrialized production. The ginsenoside is used as a main component to prepare weight-loss health foods or pharmaceutical compositions. Simultaneously, the ginsenoside has functions of restraining pancreatic lipase activity and reducing body fat.

Description

Technical field: [0001] The invention relates to a preparation process of ginseng stem and leaf saponin and its new application in the pharmaceutical field. Ginseng stem and leaf saponin has the effect of inhibiting pancreatic lipase activity and can be used to prevent and improve obesity symptoms. Background technique: [0002] Current research shows that ginsenoside is the main active ingredient of ginseng, has a variety of physiological activities, and has been widely used in clinical and health care. According to recent research reports, ginseng root has anti-obesity effects. Ginseng stems and leaves mainly contain chemical components such as ginsenosides, polysaccharides, amino acids, proteins, and volatile oils, and the amount of ginsenosides contained in ginseng stems and leaves is higher than that of ginseng taproot. There is no report on the anti-obesity effect of ginseng stems and leaves saponins. Invention content: [0003] The invention provides a preparation ...

Claims

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Application Information

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IPC IPC(8): A61K36/258A61P3/04A23L1/30A61K127/00A61K135/00A23L33/105
Inventor 郑毅男李伟李慧萍张晶张伟
Owner JILIN AGRICULTURAL UNIV
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