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Gel ointment for treating pointed condyloma

A technology for gel ointment and condyloma acuminatum, applied in the field of gel ointment, can solve problems such as inconvenience of patients, and achieve the effects of avoiding corrosion, inhibiting the growth of fungi, and being easy to adhere to

Inactive Publication Date: 2009-09-09
大连永兴生物医药孵化器有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Therefore, these drugs need to be used with extra care, causing inconvenience to patients

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0014] In the gel-ointment formulation for the treatment of condyloma acuminata 1000 g:

[0015] (1) The medicine gentian 70g, polygonum cuspidatum 80g, and rhubarb 70g in the formula are extracted into 2000g (ml) of extract for subsequent use; (embodiment 2 and embodiment 3 all use this extract.)

[0016] (2) 200g sodium carboxymethylcellulose and 100g carbomer are mixed evenly;

[0017] (3) Pour 300g of deionized water, 50g of glycerin, and 10g of Tween-80 into (2), and fully stir at a temperature of 50°C to 90°C to prepare an ointment base;

[0018] (4) 80g Brucea javanica oil and 260g drug extract are poured into (3), and then fully stirred to prepare the gel ointment for treating condyloma acuminatum.

Embodiment 2

[0020] In the gel-ointment formulation for the treatment of condyloma acuminata 1000 g:

[0021] (1) 200g sodium carboxymethylcellulose and 100g chitosan are mixed evenly;

[0022] (2) Pour 300g of deionized water, 50g of glycerin, and 10g of Tween-80 into (1), and fully stir at a temperature of 50°C to 90°C to prepare an ointment base;

[0023] (3) 80g Brucea javanica oil and 260g drug extract are poured into (2), and then fully stirred to prepare the gel ointment for treating condyloma acuminatum.

Embodiment 3

[0025] In the gel-ointment formulation for the treatment of condyloma acuminata 1000 g:

[0026] (1) 150g sodium carboxymethylcellulose, 150g sodium starch glycolate are mixed evenly;

[0027] (2) Pour 300g of deionized water, 50g of glycerin, and 10g of Tween-80 into (1), and fully stir at a temperature of 50°C to 90°C to prepare an ointment base;

[0028] (3) 80g Brucea javanica oil and 260g drug extract are poured into (2), and then fully stirred to prepare the gel ointment for treating condyloma acuminatum.

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PUM

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Abstract

The invention relates to a gel ointment for treating pointed condyloma. Carboxymethylcellulose sodium and other gels are compounded to form an ointment substrate. The carried medicaments comprise oleum fructus bruceae, gentian, giant knotweed and rhubarb. The gel ointment has the advantages that: 1, the ointment has functions of stanching and absorbing tissue fluid; 2, the ointment has the function of inhibiting the growth of fungus; 3, due to the wrapping effect of a gel carrier, the medicaments are milder and avoid corrosive effect on the peripheral skin of a condyloma body and mucosa; 4, the gel ointment can slowly and lastingly release the medical compositions, thereby improving the curative effect; 5, the ointment has biological adhesion so that the gel ointment is easy to adhere on an affected part; and 6, the gel ointment is more convenient to use.

Description

technical field [0001] The invention relates to a gel ointment loaded with javanica javanica oil, gentian, knotweed and rhubarb, and sodium carboxymethylcellulose for treating condyloma acuminatum and other gels. Background technique [0002] At present, for the treatment of condyloma acuminatum, in addition to surgery, laser, and cryotherapy, the ideal oil, liniment, and single or compound liniment made from Brucea javanica or a compound of Brucea javanica and podophyllotoxin. Due to the lack of sustained-release performance of the carrier, Brucea javanica can corrode the skin and mucous membranes around the warts in addition to the effect of corroding warts. When the dosage is too large, itching, pain, redness and swelling will occur, and the dosage needs to be reduced or stopped. For liniment containing podophyllotoxin, petroleum jelly should be used to protect the skin and mucous membranes around the wart. Therefore, these drugs need to be used with great care and inco...

Claims

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Application Information

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IPC IPC(8): A61K47/38A61K47/36A61K47/34A61K47/32A61K47/40A61K47/42A61K36/708A61K9/06A61P31/20A61K47/10A61K47/26
Inventor 冯伯智滕锡山
Owner 大连永兴生物医药孵化器有限公司
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