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Gel patch for treating motion sickness and preparation method thereof

A technology of motion sickness and gel, which is applied in the field of gel patch for the treatment of motion sickness and its preparation, and can solve the problems of easy-to-contaminate clothing, low cohesion, and low sticking fastness

Inactive Publication Date: 2009-07-01
TIANJIN ZHONGBAO PHARMACY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The purpose of the present invention is to optimize the traditional Chinese medicine formula for the treatment of motion sickness, integrate the advantages of molecular gel and hydrogel, and overcome the shortcomings of general gel dosage forms such as low fastness, small cohesive force, and easy to pollute clothes.

Method used

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Examples

Experimental program
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Effect test

Embodiment

[0028] Prescription: ginger 50kg, orange peel 10kg, Huoxiang 10kg, borneol 5kg

[0029] Transdermal Penetration Enhancer Isopropyl Myristate 6kg

[0030] Isopropanol 2kg

[0031] Ginger Extract 25kg

[0032] Orange Peel Extract 5kg

[0033] Patchouli Extract 5kg

[0034] ice flakes 5kg

[0035] Molecular Gel 5% Dioctadecyldimethylammonium Chloride

[0036] 70% cyclohexane, 25% 2-ethoxyethanol 100kg

[0037] Hydrogel 8% Sodium Polyacrylate, 2% Polyvinylpyrrolidone

[0038] 2% sodium carboxymethylcellulose, 20% propylene glycol

[0039] 20% glycerol, 1% micronized silica gel, 47% deionized water 400kg

[0040] Take 70kg of cyclohexane and 25kg of 2-ethylethanol in a stirrer, add 5kg of dioctadecyldimethylammonium chloride and 35kg of medicinal materials to extract volatile oil, heat and stir at 70°C until the mixture is uniform, and gradually cool down until room temperature forms Gel, spare. Take 32kg sodium polyacry...

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Abstract

The present invention discloses a gel patch for treating motion sickness and a preparing method thereof. The patch of the invention is composed of a back lining layer, an adhesive layer and a protecting layer. The invention is characterized in that the adhesive layer in the patch is mainly composed by mixing Chinese medicinal herbs, molecular gel, hydrogel and bleeding promoting agent. The composition and weight parts of Chinese medicinal herbs are as follows: 1-50 parts of fresh ginger, 1-25 parts of orange peel, 1-25 parts of agastache rugosa and 1-25 parts of bornyl alcohol. The weight part of each component in the adhesive layer is as follows: 1-30 parts of Chinese medicinal herb extract, 50-200 parts of molecular gel, 100-500 parts of hydrogel and 1-20 parts of bleeding promoting agent. The gel patch of the invention has the advantages of remarkable preventing and treating effect to motion sickness, little side effect, smooth medicine releasing, small excitation to skin, easy carrying, and convenience for the using of patients suffering from motion sickness.

Description

technical field [0001] The invention belongs to the technical field of transdermal drug delivery preparations, and relates to a gel patch for treating motion sickness and a preparation method thereof. Background technique [0002] Motion sickness, seasickness and airplane sickness are collectively referred to as motion sickness in medicine, also known as motion sickness. The main reason is that when taking a vehicle, the position of the human body is constantly changing due to the obvious bumps, lifts and rotations, and some people's balance organs cannot adapt to such frequent changes, and their cochlear vestibular nerve function will be temporarily disordered. Coupled with factors such as fear, irritability, and visceral shock, dizziness, headache, nausea, and vomiting will occur. When motion sickness is severe, collapse and shock may even occur. [0003] Molecular gel is a gel factor (some small molecular organic compounds) interacting through non-covalent bonds in a no...

Claims

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Application Information

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IPC IPC(8): A61K36/9068A61K9/70A61K47/12A61K47/14A61K47/18A61K47/24A61K47/28A61K47/38A61K47/40A61P1/08A61K31/045
Inventor 高惠明周英超方昊李扬
Owner TIANJIN ZHONGBAO PHARMACY
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