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Multifunctional high-efficient calcium replenishing agent and preparation thereof

A calcium supplement, multi-functional technology, applied in food preparation, application, food science and other directions, can solve the problems of high acute toxicity, difficult absorption, and unfavorable calcium supplementation.

Inactive Publication Date: 2008-12-17
辽宁美天佳生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The earliest calcium agent used is inorganic calcium, such as calcium carbonate, calcium oxide, calcium hydroxide, calcium phosphate, etc. The characteristics of inorganic calcium are that it is simple to prepare, cheap and easy to get, but it has the following disadvantages: (1) calcium is made of inorganic calcium It exists in the form of ions, which is difficult to be absorbed by the human body and has low bioavailability; (2) Inorganic calcium has a bitter taste and consumes a large amount of gastric acid after taking it, which has a stimulating effect on the stomach; (3) It is easily hydrolyzed in the intestinal tract and is prone to CO 3 2- 、PO 4 3- , phytic acid, etc. generate insoluble substances that affect absorption
For example, the calcium content of calcium gluconate is low, and the price is high, which is difficult for users to accept
The acid radicals of some organic calcium salts accumulate in the body and cause adverse effects. Gluconate radicals are decomposed into glucose, which is unfavorable to those who are both calcium deficient and diabetic; Calcium has high acute toxicity, which can easily lead to death due to kidney stones and myocardial spasm. Acetate has other undecided issues. At the same time, the production of calcium acetate has a strong odor, which has adverse effects on production workers and the environment.
Calcium citrate is slightly soluble in water, which limits its application
The newly developed third-generation calcium supplement is an amino acid complex of calcium, the most representative of which is calcium glycinate, which is characterized by almost eliminating the acid and astringent taste unique to calcium salts, but the price is relatively high and difficult to obtain. Soluble in water, so its application is also limited
Generally, the amino acid calcium salt obtained by the reaction of amino acid and calcium is insoluble or hardly soluble in water, which reduces the effect of calcium supplementation
In addition, according to the sampling inspection by the national quality supervision and inspection department, it was found that the lead content in most calcium health products exceeded the standard, and there were problems such as potential safety hazards

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0015] Weigh 53.2 grams of L-aspartic acid and 17.6 grams of L-ascorbic acid and dissolve them in 200ml of water, heat them in a water bath to 50°C to dissolve them completely, then weigh 18.5 grams of active calcium and slowly add them to L-ascorbic acid and L-ascorbic acid In the mixed solution of amino acid, stirred and reacted for 1.5 hours, filtered after the precipitate was completely separated out, refined, dried and pulverized to obtain 76.6 grams of white L-ascorbic acid-L-aspartic acid calcium powder, the solubility in water was 31.7g / 100ml, the The product not only does not have the astringent taste of calcium, but also has a good taste and is non-irritating.

Embodiment 2

[0017] Weigh 66.5 grams of L-aspartic acid and 176 grams of L-ascorbic acid and dissolve them in 500ml of water, heat them in a water bath to 60°C to dissolve them completely, then weigh 80 grams of oyster calcium carbonate and slowly add them to L-ascorbic acid and L-ascorbic acid In the mixed solution of aspartic acid, stirred and reacted for 3 hours, filtered after the precipitation was completely separated out, refined, dried and pulverized to obtain 260.5 grams of white L-ascorbic acid-L-aspartic acid calcium powder, the solubility in water was 23.2g / 100ml, This product not only does not have the astringent taste of calcium, but also has a good taste and is non-irritating.

Embodiment 3

[0019] Weigh 133 grams of L-aspartic acid and 176 grams of L-ascorbic acid and dissolve them in 600ml of water, heat them in a water bath to 40°C to dissolve them completely, then weigh 74 grams of active calcium and slowly add them to L-ascorbic acid and L-ascorbic acid In the mixed solution of amino acid, stirred and reacted for 2 hours, filtered after the precipitate was completely separated out, refined, dried and pulverized to obtain 313.7 grams of light yellow-white L-ascorbic acid-L-aspartic acid calcium powder, the solubility in water was 39.4g / 100ml, This product not only does not have the astringent taste of calcium, but also has a good taste and is non-irritating.

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PUM

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Abstract

The invention relates to a nutrient supplement for calcium supplementation, in particular to a multi-functional high-efficient calcium supplemental agent and a preparation method thereof which belong to the field of nutritious and health care products. The product of the invention selects inorganic calcium salt, L-ascorbic acid, L-aspartic acid for carrying out the reaction to prepare L-ascorbic acid-L-aspartic acid calcium; and the L-ascorbic acid-L-aspartic acid calcium can be prepared into health care foods with different forms such as tablets, granules, capsules, oral liquor and other after being added with necessary excipients. The product has good taste, no bitter taste and no gastrointestinal tract stimulation; the product has easy absorption, good safety and multiple nutritious health care functions. The product can more easily enter various parts of the human body through the passive diffusion, the transport or active transport and other different modes when in lack of calcium of the human body particularly, thereby meeting the needs on the calcium element by various tissues of the human body.

Description

technical field [0001] The invention relates to a nutrient supplement for calcium supplementation, in particular to a multifunctional high-efficiency calcium supplement and a preparation method thereof, belonging to the field of nutrition and health food. Background technique [0002] Calcium is the foundation of human life and the most abundant mineral element in the human body. It participates in the whole life process. Many diseases are related to calcium deficiency. Calcium can only be ingested by people from "drink" and "food". At present, the lack of calcium in our country is unquestionable. The results of many nutritional surveys in my country have proved that calcium is the most deficient nutrient. It is necessary to provide universal and reasonable calcium supplementation to our people. However, for many diseases and symptoms caused by calcium deficiency, the effect of calcium supplements is not satisfactory. The development and production of safe, efficient, econ...

Claims

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Application Information

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IPC IPC(8): A23L1/304A23L1/305A23L1/302A23L33/16A23L33/17
Inventor 李卫平
Owner 辽宁美天佳生物科技有限公司
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