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Composite nasal cavity preparations for curing allergic rhinitis

A technology for allergic rhinitis and preparations, applied in the field of medicine, can solve the problems of long cycle, poor treatment effect, and large side effects of drugs, etc., and achieve the effect of safe preparations, rapid action, and symptom improvement

Inactive Publication Date: 2008-09-03
GUANGDONG PHARMA UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, it can be seen from clinical reports that the existing method of treating allergic rhinitis using the above-mentioned single drug has poor therapeutic effect, long cycle, and large side effects of drugs.
At present, there is a lack of an effective, safe, rapid-acting, and comprehensive nasal compound preparation for controlling the symptoms of allergic rhinitis

Method used

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  • Composite nasal cavity preparations for curing allergic rhinitis
  • Composite nasal cavity preparations for curing allergic rhinitis
  • Composite nasal cavity preparations for curing allergic rhinitis

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0037] According to the following formula, nasal drops are prepared by adding auxiliary materials according to conventional pharmaceutical methods.

[0038] Atropine sulfate: 1%;

[0039] Chlorpheniramine: 41%;

[0040] Dexamethasone acetate: 16%;

[0041] Warin: 8%;

[0042] Accessories: balance

Embodiment 2

[0044] According to the following formula, nasal spray is prepared by adding auxiliary materials according to conventional pharmaceutical methods.

[0045] Anisodamine: 7%;

[0046] Diphenhydramine: 35%;

[0047] Hydrocortisone Sodium Phosphate: 22%;

[0048] P-light ephedrine: 14%;

[0049] Accessories: balance

Embodiment 3

[0051] According to the following formula, the ointment is prepared by adding auxiliary materials according to conventional pharmaceutical methods.

[0052] Anisodamine: 4%;

[0053] Chlorpheniramine: 38%;

[0054] Dexamethasone acetate: 19%;

[0055] Warin: 11%;

[0056] Accessories: balance

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PUM

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Abstract

The invention discloses a compound nasal preparation for the treatment of allergic rhinitis, which is composed of an anti-M cholinergic drug, an antihistamine drug, a hormone, a local vasoconstriction drug and the rest amount of medicine auxiliary materials for compatibility. The invention obtains the compound nasal preparation which has a reasonable pharmaceutical combined formula and can produce the great synergy by screening, the compound nasal preparation is safe, effective, rapid in action and can comprehensively control and fundamentally improve the symptoms of the allergic rhinitis, as well as solve the technical problem of fundamentally improving or curing the allergic rhinitis.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to a compound nasal cavity preparation for treating allergic rhinitis. Background technique [0002] Allergic rhinitis, also known as allergic rhinitis (Allergic Rhinitis), is an allergic reaction of nasal mucosa, characterized by nasal itching, sneezing, rhinorrhea, and swelling of nasal mucosa, with an incidence rate of 10% to 40%. . The etiology of allergic rhinitis is usually due to the special sensitive reaction of nasal mucosa, the antigen is inhalation (dust in the air, house dust, and mold), food, bacteria or physical factors. [0003] Allergic rhinitis generally adopts the following treatments clinically at present: desensitization therapy, namely immunotherapy; non-specific treatment; antihistamine drug treatment; hormone therapy; and surgical treatment. However, it can be seen from clinical reports that the existing method of treating allergic rhinitis usin...

Claims

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Application Information

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IPC IPC(8): A61K45/06A61P11/02A61K31/46A61K31/4402A61K31/573A61K31/4164
Inventor 程靖刘俊捷
Owner GUANGDONG PHARMA UNIV
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