'Zanyudan' oral preparation and preparation thereof
A technology of oral preparation and zanyudan, applied in the field of medicine, can solve the problems of inaccurate dosage, inability to commercialize, large dosage of traditional Chinese medicine decoction, etc.
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Embodiment 1
[0050] Embodiment one: "Zan Yudan" extract 1 (extract) preparation method
[0051] Prescription: 24 grams of Rehmannia glutinosa, 12 grams each of Cistanche, Morinda officinalis, Epimedium, and Eucommia, 6 grams of Cnidium, 12 grams of leek seeds, 18 grams of Angelica, 12 grams of curculigo, 6 grams of aconite, 24 grams of Atractylodes macrocephala, wolfberry 18 grams of cornel, 12 grams of dogwood, 6 grams of cinnamon
[0052] Preparation method: cleanly select the medicinal materials of the prescription, weigh each medicinal material according to the prescription amount, add 6 to 15 times the amount of water to soak for 2-10 hours, heat and boil for 2-3 times, and combine the extracts; the water extracts stand still After 12-48 hours, filter the supernatant, concentrate under reduced pressure to obtain about 30.4 g of water extract.
Embodiment 2
[0053] Embodiment two: "Zan Yudan" extract 2 (dry powder) preparation method
[0054] Prescription: 24 grams of Rehmannia glutinosa, 12 grams each of Cistanche, Morinda officinalis, Epimedium, and Eucommia, 6 grams of Cnidium, 12 grams of leek seeds, 18 grams of Angelica, 12 grams of curculigo, 6 grams of aconite, 24 grams of Atractylodes macrocephala, wolfberry 18 grams of cornel, 12 grams of dogwood, 6 grams of cinnamon
[0055] Preparation method: cleanly select the medicinal materials of the prescription, weigh each medicinal material according to the prescription amount, add 8 to 10 times the amount of water to soak for 2-8 hours, heat to boiling and extract 2-3 times, combine the extracts; the water extracts stand still After 12-48 hours, the supernatant was collected by filtration, concentrated under reduced pressure, and spray-dried to obtain about 32.8 g of water extract as a dry powder.
Embodiment 3
[0056] Embodiment three: "Zan Yudan" oral solid preparation preparation method
[0057] (1) Preparation of "Zanyudan" granules
[0058] prescription:
[0059] "Zanyudan" Extract 1 10-90%
[0060] Starch 5.0-70%
[0061] Dextrin 2.0-20%
[0062] Xylitol 5.0-20%
[0063] Methyl sorbate 0.001-2.0%
[0064] Preferred Prescription:
[0065] "Zanyudan" extract 1 30.4g
[0066] Starch 3.0g
[0067] Dextrin 3.0g
[0068] Xylitol 2.0g
[0069] Methyl sorbate 0.002g
[0070] Preparation method: Prepare the extract of "Zanyudan" according to the method in Example 1, add the prescribed amount of auxiliary materials to make granules according to the conventional method, dry at low temperature, pack and make three bags, each bag is 12.8g.
[0071] (2) Preparation of "Zan Yudan" tablet:
[0072] (1) Ordinary tablet prescription:
[0073] "Zanyudan" Extract 2 5.0-90%
[0074] Starch 5.0-50%
[0075] Dextrin 2.0-20%
[0076] Microcrystalline Cellulose 5.0-20%
[0077] Talc 0...
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