Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Method for calibrating machines for the analysis of characteristic parameters of the blood connected to its density, such as erythrocytesedimentation rate and/or red corpuscles aggregation rate

A technology of erythrocyte sedimentation and red blood cells, applied in sedimentation analysis, scientific instruments, particle and sedimentation analysis, etc., can solve different problems

Active Publication Date: 2008-07-23
ALIFAX
View PDF1 Cites 8 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, with these controllers, each measurement system used obtains a different ESR value

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Method for calibrating machines for the analysis of characteristic parameters of the blood connected to its density, such as erythrocytesedimentation rate and/or red corpuscles aggregation rate
  • Method for calibrating machines for the analysis of characteristic parameters of the blood connected to its density, such as erythrocytesedimentation rate and/or red corpuscles aggregation rate

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0045] Referring to FIG. 1 , the method according to the invention is used to calibrate an instrument 10 that detects erythrocyte sedimentation rate (ESR) by measuring the change in optical density of a blood sample 12 arriving from, for example, a test tube 13 .

[0046] The instrument 10 comprises a tube 15 defining a measurement volume 16 into which a blood sample 12 to be analyzed is injected and whose flow is stopped abruptly, producing a characteristic curve of optical density. The latter is called the transmitted light intensity-time curve and is indicated by the letter "S" in FIG. 2 .

[0047] Obviously, other methods known in the art for measuring the erythrocyte sedimentation rate (ESR) of the blood sample 12 by changing the absorbance can be used to obtain the transmitted light intensity-time curve.

[0048] On curve S of FIG. 2, point "a" refers to where the optical density value of the blood sample 12 is substantially constant, while indicated point "b" represents...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

A method for calibrating an instrument (10) adapted to perform the analysis of a blood sample (12) by measuring erythrocyte sedimentation rate (ESR) and / or erythrocyte aggregation, wherein said measurement is performed by using a Realized by the optical density kinetics obtained by measuring the optical density change of a blood sample (12) over a certain time interval, the method comprises the step of measuring, wherein by the same instrument (10) that performs the optical density measurement on said blood sample (12) The optical density of at least two latexes (23a, 23b, 23c) or turbidimetric samples is measured. Each of said at least two latexes (23a, 23b, 23c) has a known optical density that is reproducible, measurable and mutually distinct. The method also includes a comparison step in which the difference between the optical density values ​​of said latex (23a, 23b, 23c) obtained from measurements made by the instrument (10) and known optical density values ​​is calculated to allow determination of At least one correction factor may be used to calibrate said instrument (10).

Description

technical field [0001] The invention relates to a method for calibrating or setting and controlling an instrument suitable for analyzing a blood sample and for eg measuring the sedimentation rate of blood cell fractions. [0002] More precisely, the measurement concerns the sedimentation velocity of erythrocytes (erythrocyte sedimentation rate, ESR) and / or the aggregation rate of erythrocytes, and is carried out by using an optical density kinetic called a transmitted light intensity-time curve (syllectogram). Background technique [0003] In the field of blood analysis, it is known to measure the sedimentation velocity (ESR) of blood cell fractions to assess the presence of eg inflammatory pathologies. [0004] Apparatus and techniques for measuring ESR are known, such as described in European patent application EP-A-1098188 published in the name of the applicant, which uses light emitting means and detection means placed on opposite sides of a measurement volume . [000...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): G01N15/05G01N21/82
CPCG01N15/05
Inventor 阿尔弗雷多·乔蒂P·伽里亚诺朱塞佩·乔蒂
Owner ALIFAX
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com