Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Method for preparing product for reducing blood sugar

A product and blood sugar technology, applied in the field of preparation of blood sugar lowering products, can solve problems such as lack of enzyme activity, and achieve the effects of no toxic and side effects, simple production process and good hypoglycemic effect

Active Publication Date: 2008-07-16
NORTHWEST NORMAL UNIVERSITY
View PDF5 Cites 2 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In the above-mentioned numerous patent documents, the research on the hypoglycemic mechanism of the product often only studies the blood sugar level and antioxidant system of model animals, rarely involves the toxic and side effects of the product, and lacks the research on the liver, kidney and other organs. Study on Enzyme Activity in Responding to Organ Damage

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Method for preparing product for reducing blood sugar
  • Method for preparing product for reducing blood sugar
  • Method for preparing product for reducing blood sugar

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0039] A kind of preparation method of blood sugar lowering product of the present invention, comprises the following steps:

[0040] 1) Weigh 100g of Cynomorium dry product, crush it; add 450ml of methanol or petroleum ether, reflux at 70°C for 1.5 hours; suction filter under the condition of 0.07MPa, use water as solvent, and extract for 60 minutes, of which Cynomorium The weight ratio of raw material and water is 1: 8; Then add ethanol to filtrate, make ethanol content account for 75% of total volume, leave standstill at room temperature for 20 hours, centrifuge under the rotating speed of 3500 rev / min then, collect precipitation; Dry the precipitate at 40°C and 0.06MPa for 11 hours to obtain substance A;

[0041] 2) Weigh 50g of substance A, dissolve it with 80 times the weight of water, heat the aqueous solution containing substance A to 60°C, then add 5u / 100ml papain to carry out enzymatic hydrolysis for 1.5 hours, and then use chloroform and normal The butanol mixture ...

Embodiment 2

[0044] A kind of preparation method of blood sugar lowering product of the present invention, comprises the following steps:

[0045] 1) Weigh 100g of Cynomorium dry product, crush it; add 550ml of methanol or petroleum ether, reflux at 80°C for 2.5 hours; suction filter under the condition of 0.09MPa, use water as solvent, extract for 120 minutes, of which Cynomorium The weight ratio of the raw material to water is 1:20; then, ethanol is added to the filtrate so that the ethanol content accounts for 80% of the total volume, and it is allowed to stand at room temperature for 30 hours, then centrifuged at a speed of 4500 rpm to collect the precipitate; Dry the precipitate at 50°C and 0.08MPa for 13 hours to obtain substance A;

[0046] 2) Weigh 50g of substance A, dissolve it with 100 times the weight of water, heat the aqueous solution containing substance A to 70°C, then add 7u / 100ml papain to carry out enzymatic hydrolysis for 2.5 hours, and then use chloroform and normal T...

Embodiment 3

[0049] A kind of preparation method of blood sugar lowering product of the present invention, comprises the following steps:

[0050] 1) Weigh 100g of Cynomorium dry product, crush it; add 500ml of methanol or petroleum ether, reflux at 75°C for 2 hours; suction filter under the condition of 0.08MPa, use water as solvent, and extract for 90 minutes, of which Cynomorium The weight ratio of raw material and water is 1: 15; Then add ethanol to filtrate, make ethanol content account for 78% of total volume, leave standstill at room temperature for 25 hours, then centrifuge at 4000 rpm to collect precipitate; Dry the precipitate at 45°C and 0.07MPa for 12 hours to obtain substance A;

[0051] 2) Weigh 50g of substance A, dissolve it with 90 times the weight of water, heat the aqueous solution containing substance A to 65°C, then add 6u / 100ml papain for enzymolysis for 2 hours, and then use chloroform and normal The butanol mixture was extracted 4 times, the upper aqueous solution ...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention relates to a preparation method of a blood sugar reducing product. The method adopts herba cynomorii as raw material, which is prepared into a curative medicinal product that is mainly used for curing chemical diabetes caused by streptozotocin (STZ) and has prominent curative effect to liver and kidney damage arising from diabetes via the steps of crashing, refluxing, pumping filtering, centrifuging, zymolysis, extracting, depressing, compressing, adjusting pH value, dialyzing and centrifuging a dialysis tubing, etc. The invention fully utilizes herba cynomorii that is parasitized in zygophyllaceae Nitraria L. plants and pervasive in Gansu Province, Qinghai Province and Inner Mongolia Autonomous Region, and utilizes the excellent resource superiority of sufficient reserves to develop the product, which has a promising market prospect and broad economic benefits.

Description

technical field [0001] The invention relates to a preparation method of a product for lowering blood sugar. Background technique [0002] Diabetes mellitus is a metabolic disorder syndrome characterized by chronic hyperglycemia associated with genetic factors and various environmental factors. It is a common disease that seriously endangers human health worldwide. In recent years, the incidence of diabetes has been relatively high. The incidence rate of the general population in my country is 1-2%, and that of those over 40 years old is 3-4%. The incidence rate of the elderly is even higher. The incidence in Western industrialized countries is 2-4%. Early diabetes has no obvious clinical symptoms and is difficult to detect. In my country and western industrialized countries, a large number of diabetic patients have not been diagnosed and treated in time. In addition, there are many complications of diabetes. At present, effective preventive measures for diabetes are lacking...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K36/185A61P3/10
Inventor 张继吴依茜王云普王春霞王俊龙张亚楠赵保堂
Owner NORTHWEST NORMAL UNIVERSITY
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com