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Method of preparing antimicrobial hemostasis Chinese medicine-containing biological dressings

A technology of biological dressings and traditional Chinese medicines, applied in medical science, bandages, absorbent pads, etc., can solve problems such as toxic side effects, reduced antibacterial properties, and reduced active amino groups, and achieve significant hemostatic effects and good biocompatibility

Inactive Publication Date: 2008-03-12
UNIV OF ELECTRONICS SCI & TECH OF CHINA ZHONGSHAN INST
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Problems solved by technology

"Journal of the Academy of Military Medical Sciences" (1993, 17 (1)) reported the research of chitosan~norfloxacin burn dressing, this dressing is not a pure natural material, and the synthetic drug therein has certain toxic and side effects
Moreover, the chitosan used in this type of product has undergone physical recrystallization or chemical modification with a high degree of substitution during the preparation process, which reduces the active amino group of the product, reduces the antibacterial property, and weakens the ability to control wound infection.

Method used

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Examples

Experimental program
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Effect test

Embodiment Construction

[0006] (1) Extraction of active ingredients of antibacterial and hemostatic traditional Chinese medicine

[0007] Weigh an appropriate amount of traditional Chinese medicines such as Galla gall, Panax notoginseng, etc., decoct twice, add 8 to 20 times of water each time, and decoct for 2 hours. Filter and combine the filtrates. Concentrate the decoction to 1 / 5 of the original volume to obtain a concentrate. Add 2 times the volume of 95% ethanol into the concentrated solution until the precipitation is complete, and filter with suction to obtain the filtrate. The filtrate is distilled to recover ethanol, and the extract containing the active ingredients of the antibacterial and hemostatic traditional Chinese medicine is obtained.

[0008] (2) Manufacture of biological dressings containing antibacterial and hemostatic traditional Chinese medicine

[0009] Use cotton, gauze or non-woven fabric as the base material, impregnate the base material with 0.5-5% glycerin, 75-95% deac...

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Abstract

The present invention is a biological dressing produced by the extraction liquid of the Chinese medicine with antibacterial and homeostasis properties comprising the soaking gall and the notoginseng, which takes the cotton, gauze or non-woven fabrics as the substrate and the chitosan as the membrane forming material. The present invention can be applied in the wound dressing for the burning wound and the injury. The present invention has characteristics of good biocompatibility, safety property, absorbing the wound exudates, antibacterial property, and homeostasis property and accelerating the healing in the wound. The main material of the present invention is the natural material.

Description

Technical field [0001] The invention relates to a manufacturing method of a pure natural biological dressing containing antibacterial and hemostatic traditional Chinese medicines which can be widely applied to wounds. Background technique [0002] Wound dressings are divided into traditional dressings, biological dressings and synthetic dressings according to their material composition. Among them, biological dressings have the characteristics of good biocompatibility, safety, and quick wound healing, so they are favored by people. CN1275408 has reported the technology that extracts biologically active substance and collagen to prepare biological dressing from animal's epithelium and dermal tissue; CN1380109 has reported a kind of chitosan, collagen and calcium alginate composite sponge biological dressing and its manufacturing process; "Chinese Biomedicine Engineering Journal (1996, 15 (2)) reported that chitosan, gelatin and glycerin were used as basic raw materials, and ...

Claims

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Application Information

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IPC IPC(8): A61L15/40A61L15/44
Inventor 刘常坤吴燕芬李晶
Owner UNIV OF ELECTRONICS SCI & TECH OF CHINA ZHONGSHAN INST
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