Chinese medicine preparation for treating stomach-ache and its preparation process

A traditional Chinese medicine preparation and preparation technology, applied in the field of medicine, can solve the problems of being inferior to new dosage forms, difficulty in implementation, and unknown process parameters, etc.

Inactive Publication Date: 2007-09-19
BEIJING YINKERUISI BIOLOGICAL PODUCTS RES INST
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Qi stagnation stomach pain preparations such as granules, tablets, and capsules have gained a share in the market due to their better curative effect. However, with the development of new technology and technology of preparations, ordinary preparations are far behind the new ones due to the limitations of some indicators. dosage form
In the prior art, the patent application number is 01100075.9, and the name of the invention is: Nano Qi stagnation gastric pain preparation drug and its preparation method. It is easy to popularize and use; the patent application number is 200510008493.4, and the name of the invention is: a traditional Chinese medicine for treating gas stagnation stomach pain and its preparation method. The invention discloses a preparation for treating gas stagnation stomach pain and provides granules, tablets, capsules, and dispersible tablets . The preparation method of micropill capsules. The micropill capsules in this invention are micropill capsules prepared by extracting volatile oil from Fructus Aurantii Fructus and Rhizoma Rhizoma Cyperi.

Method used

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  • Chinese medicine preparation for treating stomach-ache and its preparation process

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0077] Bupleurum 1071.3g Corydalis Corydalis (burnt) 1190.4g Citrus aurantium 1190.4g

[0078] Rhizoma Cyperi (burned) 1190.4g Paeoniae Alba 1428.7g Licorice (burned) 594.7g

[0079] The above six flavors, except 142.8g of Corydalis Corydalis and 285.7g of Radix Paeoniae Alba, which are crushed into fine powder, add 10 times the amount of water to decoct the remaining six flavors of Fructus aurantii, each time for 1.5 hours, combine the decoction, concentrate the filtrate to a clear paste, add the above fine Mix the powder evenly, dry under reduced pressure, crush into fine powder, add appropriate amount of microcrystalline cellulose, respectively pass through a 100-mesh sieve, mix well, make soft material with 30% distilled water, extrude and spheronize (the aperture of the sieve plate is 1.0mm, extrude The speed is 30rpm, the spheronization speed is 50Hz, and the spheronization time is 6min) to make pellets, and make 1000g, to get final product.

Embodiment 2

[0081] Bupleurum 1071.3g Corydalis Corydalis (burnt) 1190.4g Citrus aurantium 1190.4g

[0082] Rhizoma Cyperi (burned) 1190.4g Paeoniae Alba 1428.7g Licorice (burned) 594.7g

[0083] The above six flavors, except 142.8g of Corydalis Corydalis and 285.7g of Radix Paeoniae Alba, which are crushed into fine powder, add 10 times the amount of water to decoct the remaining six flavors of Fructus aurantii, each time for 1.5 hours, combine the decoction, concentrate the filtrate to a clear paste, add the above fine The powder is mixed evenly, dried under reduced pressure, pulverized into fine powder, added with appropriate amount of microcrystalline cellulose and lactose, mixed evenly, made into soft material, and made into 1000g of concentrated pellets by law.

Embodiment 3

[0085] Bupleurum 952.3g Yanhusuo (burnt) 1071.4g Citrus aurantium 1071.4g

[0086] Rhizoma Cyperi (burned) 1071.4g Paeoniae Alba 1309.6g Licorice (burned) 475.8g

[0087] The above six flavors, except 128.6g of Corydalis Corydalis and 261.9g of Paeoniae Alba, which are crushed into fine powder, add 8 times the amount of water to decoct the other six flavors such as Citrus aurantium, the first time is 2.0 hours, and the second time is 1.5 hours. Combine the decoction and concentrate the filtrate To clear paste, add the above fine powder and mix evenly, dry under reduced pressure, crush into fine powder, add appropriate amount of microcrystalline cellulose and starch, pass through 100 mesh sieve respectively, mix well, make soft material with 20% distilled water, and make micro Pills or concentrated pills, made into 1000g, ready to serve.

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Abstract

The invention relates to a Chinese materia medica preparation for treating gastralgia and the preparation method thereof, which is composed of acceptable carriers on medical components and / or pharmacy, wherein the said medical components comprises bupleurum, corydalis tuber, bitter orange, cyperirhizome, white peony root, glycyrrhiza, with effects of dispersing the liver depression and gastric analgesia. The preparation mainly refers to pellet, concentrated pill, and sustained-release preparation. The preparation has advantages of large gastrointestinal distribution area, high bioavailability, small excitability, good fluidity, even size, easy to coat and divide dose comparing with the other oral dosages.

Description

technical field [0001] The invention relates to a traditional Chinese medicine preparation for treating stomach and wrist pain and a preparation method thereof, belonging to the technical field of medicine. technical background [0002] Epigastric pain is mainly a chronic and recurrent disease. Disharmony between the spleen and the stomach is the main pathological mechanism. It is not appropriate to ventilate, such as eating too much fat, sweet, spicy, spicy or eating too much cold or raw food or hunger and fullness can lead to blockage of stomach qi. Qi stagnation stomach pain preparations such as granules, tablets, and capsules have gained a share in the market due to their better curative effect. However, with the development of new technology and technology of preparations, ordinary preparations are far behind the new ones due to the limitations of some indicators. dosage form. In the prior art, the patent application number is 01100075.9, and the name of the invention...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8905A61K9/08A61K9/10A61K9/16A61K9/20A61K9/46A61K9/48A61P1/04
Inventor 张保献
Owner BEIJING YINKERUISI BIOLOGICAL PODUCTS RES INST
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