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A technology for diabetic nephropathy and capsules, applied in the directions of capsule delivery, urinary system diseases, metabolic diseases, etc., can solve problems such as insufficient therapeutic effect, and achieve the effects of inhibiting glomerular hypertrophy, reducing GBM thickness, and correcting lipid metabolism disorders.
Active Publication Date: 2009-08-12
BEIJING TRT PHARMA
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Problems solved by technology
At present, most scholars focus on the research of pathogenesis in the treatment of diabetic nephropathy, and the therapeutic effect is not significant enough.
Method used
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[0021] The ingredients and parts by weight of the formula are: ginseng 70, astragalus 125, raw land 125, crocus 95, Ophiopogon japonicus 125, yam 100, coptis 60, schisandra 55, rhubarb 60, leech 65, cinnamon 55, grass fruit 60. Fructus Fructus (refined) seed 55, cumin 55; cinnamon, grass fruit, schisandra, cumin with supercritical CO 2 Extract the volatile oil, collect the volatile oil, include it with β-cyclodextrin, dry it, pulverize it into a fine powder, and use it for later use; add 5-10 times the amount of 50-95% ethanol to the extracted medicinal residues and the other ten flavor components of the formula to extract two. times, for 2 hours each time, combine the extracts, recover ethanol, concentrate to extract with a relative density of 1.20-1.30, mix well, dry, pulverize into fine powder, add the above-mentioned β-cyclodextrin inclusion compound, and mix well , prepared into capsules.
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Abstract
The invention relates to a capsule for treating diabetic nephropathy, which can effectively treat diabetic nephropathy and has remarkable curative effect. Technical solution: a capsule for treating diabetic nephropathy, characterized in that: the raw materials of the formula are ginseng, astragalus, rehmannia, scrophulariae, radix radices, yam, berberine, schisandra, rhubarb, leech, cinnamon, grass fruit, toosendan (refined) seeds, fennel; cinnamon, grass fruit, schisandra, and fennel extract volatile oil with supercritical CO2, collect volatile oil, wrap with β-cyclodextrin, dry, grind into fine powder, and set aside; the medicine after extraction Add 5-10 times the amount of 50-95% ethanol to extract the slag and the other ten flavors of the formula twice, concentrate to extract with a relative density of 1.20-1.30, mix well, dry, crush into fine powder, add the above β -Cyclodextrin inclusion compound, mixed, prepared into capsules.
Description
Technical field: [0001] The present invention relates to a capsule for treating diabetic nephropathy. Background technique: [0002] Diabetic nephropathy TCM syndrome differentiation belongs to the following three syndrome types: deficiency of liver and kidney yin, internal resistance of phlegm; deficiency of qi and yin, internal resistance of phlegm; deficiency of yin and yang, internal resistance of phlegm. Mainly manifested as having a clear history of diabetes mellitus with dry mouth and polydipsia, dizziness, dry eyes, hot hands, feet and heart or aversion to cold limbs, fatigue, hot flashes, night sweats or spontaneous sweating, soreness of waist and knees, short urination or Clear and long, fat tongue, dark red tongue, or ecchymosis, little coating or thin white or greasy coating, deep and thin pulse, thin string or weak count. At present, most scholars focus on the study of the pathogenesis of the treatment of diabetic nephropathy, and the therapeutic effect is not ...
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