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Medicine for treating chronic renal insufficiency and its prepn. method

A technology for renal insufficiency and insufficiency, applied in the field of preparation of the drug, can solve problems such as difficulty in meeting clinical needs

Active Publication Date: 2009-01-21
亚宝北中大(北京)制药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Niaoduqing is the only new Chinese medicine approved by the state for the treatment of chronic renal insufficiency, which is difficult to meet a large number of clinical needs

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0098] Weigh the raw materials according to the following ratio:

[0099] 400 parts of Danshen, 450 parts of Astragalus, 300 parts of Burnet, 150 parts of Rubia

[0100] 150 parts of Radix Paeoniae Rubra, 400 parts of Eucommia, 150 parts of Dipsacus, 350 parts of Sangjisheng

[0101] Nepeta 75 parts, Fangfeng 90 parts, Angelica dahurica 90 parts, Duhuo 75 parts

[0102] Sophora japonica (fried) 150 parts, rhubarb 110 parts.

[0103] The production method is as follows:

[0104] Schizonepetae, Fangfeng, Angelica dahurica, add water to lovage, steam distillation, collect volatile oil, use β-cyclodextrin, stir at constant temperature, refrigerate overnight, filter the precipitate, dry, grind finely for later use; add water to the dregs after oil extraction , decocted once more, and the liquid medicine was combined; Salvia miltiorrhiza was refluxed twice with ethanol, 1 hour each time, adding 5 times the amount of ethanol for the first time, adding 4 times the amount of ethanol...

Embodiment 2

[0106] Weigh the raw materials according to the following ratio:

[0107] 300 parts of Danshen, 400 parts of Astragalus, 200 parts of Burnet, 200 parts of Rubia

[0108] 250 parts of Paeoniae Rubra, 300 parts of Eucommia, 250 parts of Dipsacus, 333 parts of Sangjisheng

[0109] 80 parts of Nepeta, 120 parts of Fangfeng, 75 parts of Angelica dahurica, 100 parts of Duhuo

[0110] Sophora japonica (fried) 300 parts, rhubarb 75 parts.

[0111] The production method is as follows:

[0112]Schizonepetae, Fangfeng, Angelica dahurica, add water to lovage, steam distillation, collect volatile oil, use β-cyclodextrin, stir at constant temperature, refrigerate overnight, filter the precipitate, dry, grind finely for later use; add water to the dregs after oil extraction , decocted once more, and the liquid medicine was combined; Salvia miltiorrhiza was refluxed twice with ethanol, 1 hour each time, adding 5 times the amount of ethanol for the first time, adding 4 times the amount of e...

Embodiment 3

[0114] Weigh the raw materials according to the following ratio:

[0115] 200 parts of Danshen, 500 parts of Astragalus, 400 parts of Burnet, 300 parts of Rubia

[0116] 100 parts of Paeoniae Rubra, 400 parts of Eucommia, 200 parts of Dipsacus, 200 parts of Sangjisheng

[0117] Nepeta 100 parts, Fangfeng 75 parts, Angelica dahurica 150 parts, 100 parts of solitary life

[0118] Sophora japonica (fried) 100 parts, rhubarb 200 parts.

[0119] The production method is as follows:

[0120] Schizonepetae, Fangfeng, Angelica dahurica, add water to lovage, steam distillation, collect volatile oil, and set aside; add water to the dregs after oil extraction, fry again, and combine the liquid medicine; reflux Danshen twice with ethanol, 1 hour each time, the first time Add 5 times the amount of ethanol, add 4 times the amount of ethanol for the second time, combine the two extracts, recover the ethanol under reduced pressure until it has no alcohol smell, and set it aside; mixed wit...

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PUM

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Abstract

A Chinese medicine for treating chronic renal insufficiency is prepared from 14 Chinese-medicinal materials including red sage root, astragalus root, red peony root, rhubarb, etc through respectively pre-treating and proportional dispensing.

Description

1 technical field [0001] The invention relates to a medicine for treating chronic renal insufficiency, specifically a Chinese patent medicine prepared from Chinese herbal medicine, and also relates to a preparation method of the medicine. 2 background technology [0002] Chronic renal insufficiency, often developed from chronic nephritis or other diseases, has a high incidence and is difficult to treat. It is a refractory disease with poor prognosis and is recognized worldwide. At present, both Chinese and Western medicine lack effective drugs for the treatment of this disease. Most patients with chronic nephritis will eventually develop into chronic renal failure and die. Modern medicine mainly relies on hemodialysis and kidney transplantation to the treatment measures of this disease, and drug therapy is still blank. Niaoduqing is the only new Chinese medicine approved by the state for the treatment of chronic renal insufficiency, which is difficult to meet a large numbe...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/74A61K36/739A61K36/71A61K36/708A61K36/538A61K36/53A61K36/489A61K36/481A61K36/46A61K36/238A61K36/232A61K36/185A61K9/16A61K9/00A61P13/12
Inventor 杨抒宁
Owner 亚宝北中大(北京)制药有限公司
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