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Cannabinoid Compositions

a technology of compositions and cannabinoids, applied in the field of cannabinoid compositions, can solve the problems of varied amount of time and reduced bioavailability of known methods of orally administered thc, and achieve the effect of high metabolizability and fast action

Inactive Publication Date: 2022-03-24
SRE WELLNESS INC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

The present invention relates to a method of making cannabis oil hydrophilic, which involves using emulsifiers and variations in time and temperature of the reaction steps, as well as a cannabinoid emulsification made of at least one emulsifying agent, an aqueous vehicle, a base oil, cannabis oil, and caffeine or a cannabis infused sweetener. The resulting cannabinoid emulsification is bioavailable, highly metabolizable, and fast acting when ingested by the user. The invention also provides a water-soluble cannabinoid composition that is bioavailable, fast acting, and highly metabolizable. The cannabinoid infused composition comprises cannabinoid oil, alcohol, water, a compound that forms an inclusion complex with the cannabinoid oil, and a thickener. The composition is preferably fast acting and results in a bioavailable cannabinoid when ingested. The compound and thickener each comprise 0.12% to 2% of the composition. The composition can also have equal percentages of the compound and thickener.

Problems solved by technology

However, by using selective breeding techniques, Cannabis breeders can create varieties with high levels of CBD and next to zero levels of THC.
However, known methods for orally administered THC have reduced bioavailability due to low absorption and high first-pass metabolism in the digestive system.
The problem with edible Cannabis products is they take a varied amount of time to take effect due to the liver's varied ability to process the THC molecule.
In general, elixirs are healing botanicals known to address specific imbalances yet, they are not necessarily teaching the body to mimic the healing chemistry in order for the body to continue healing.

Method used

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  • Cannabinoid Compositions
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Examples

Experimental program
Comparison scheme
Effect test

example 1

[0138]A Cannabis infused chocolate is provided that is bioavailable and delivers fast acting effects of the Cannabis when ingested. The method of making such includes use of about 5 to 10 oz of a base oil of either vegetable glycerine or coconut oil. A high quality liquor such as cognac or whiskey can be added but is optional. The base oil liquid is heated to between about 120 to 220° F. The Cannabis oil extract is added equal to about 110 to 1120 mg THC. The emulsifiers are added next, generally in the following amounts: about 0.5% lecithin, 0.15% xanthan gum, about 0.1% cyclodextrin. The emulsifiers can be used individually or in combination. The hot mixture is blended in a high speed blender or other machine, run on high speed for about 2 minutes. The mixture is allowed to cool to room temperature.

[0139]After the mixture has cooled, about 10 lb of melted chocolate is added and allowed to temper before depositing in a mold, then cooling to about 55° F.

example 2

[0140]Several experiments were run using several different emulsifiers and combinations of different coconut oils: solid and liquid (MCT). (Note: liquid MCT is coconut oil that has medium chain triglyceride). Guar gum, lecithin, and cyclodextrin were tested as emulsifying agents and provided good results. However, xanthan gum was the most effective and provided the best emulsification of the oil and water, at the lowest viscosity.

[0141]The emulsification process that was determined the best had the added effect of making the THC more bioavailable by making the oleo molecule water-soluble. This had another added effect of making it fast acting, taking effect in as little as about 15 minutes.

[0142]The method used to produce the invention emulsifications, included first heating extra virgin organic coconut oil to between about 120 to about 220 degrees F. CO2 extracted Cannabis oil is added. In a high speed blender (or similar machine) coconut water is added to the coconut fat (oil) to ...

example 3

[0143]A variety of Cannabis infused products were prepared and tested in a random study group of 40 individuals. The products tested included Cannabis infused sugar, a cannabinoid / caffeine emulsification and a Cannabis infused elixir and are summarized in the tables below.

[0144]Each of the 40 individuals tested one of the products from Tables 2, 3 and 4. The breakdown of products tested was 10% (4 people) of the cannabinoid / caffeine emulsification; 20% (8 people) of cannabinoid elixirs and 70% (28 people) of the Cannabis infused sugar.

TABLE 2Cannabis infused sugar (Serving size 1 tsp)Sugar Product#1#2#3#4#5*Cannabis Oil (mg / tsp)2040204040Sugar (lbs) 5 310 3 Alcohol (oz)20124012 6Lecithin (%)** 2 2 2 1 0Cyclodextrin (%)** 0 0   0.03   0.12   0.25*The sugar used in this sample was maple sugar.**% of final product.

TABLE 3Cannabinoid / caffeine emulsification (Serving size 2 oz)Amount inComponentemulsificationTHC (per serving) 10 mgCoconut Fat (SOLID)2.75%MCT0.65%Coconut Water  96%Cyclode...

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Abstract

A cannabinoid composition including a cannabinoid oil, such as THC oil or CBD oil, one or more thickeners such as gums, and a compound that forms an inclusion complex with the cannabinoid oil. The composition may include water, and in intermediate stages can include an alcohol. The composition can also include a sweetener to make it a sugar or a syrup. In some embodiments there are no other oils in the composition.

Description

CROSS-REFERENCE TO RELATED APPLICATIONS[0001]This application is a Continuation-in-Part application of U.S. patent application Ser. No. 16 / 161,027, filed on Oct. 15, 2018, issuing as U.S. Pat. No. 10,624,844 on Apr. 21, 2020, which application is a Continuation-in-Part application of International Application No. PCT / US2017 / 027550 filed Apr. 14, 2017 and from International Application No. PCT / US2017 / 027549 filed Apr. 14, 2017, and from International Application No. PCT / US2017 / 027543 filed Apr. 14, 2017 which all claim priority to and the benefit of U.S. Provisional Application No. 62 / 323,154 filed Apr. 15, 2016 and U.S. Provisional Application No. 62 / 328,975 filed Apr. 28, 2016, and the specification and claims thereof are incorporated herein by reference.FIELD OF THE INVENTION[0002]Embodiments of the present invention relate to a method of making Cannabis oil hydrophilic using emulsifiers. More particularly, embodiments of the present invention relate to a water-soluble cannabinoid...

Claims

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Application Information

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Patent Type & Authority Applications(United States)
IPC IPC(8): A61K31/352A61K31/05A61K47/40
CPCA61K31/352A61K31/05A61K2236/37A61K2236/331A61K47/40A61K9/107A23G1/42A23G1/48A61K47/6951C08B37/0015C08L5/16C08L91/00C08L5/00
Inventor SILVER, RONALD
Owner SRE WELLNESS INC
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