Use of alpha lipoic acid as a feed additive for aquatic animals

a technology aquatic animals, which is applied in the field of use of alpha lipoic acid as a feed additive for aquatic animals, can solve the problems of fish escape, wrecked fish pens, and affecting mortality, so as to improve the feed conversion ratio and reduce mortality. , the effect of great potential for fish feed

Pending Publication Date: 2021-02-04
DSM IP ASSETS BV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

The patent text describes the use of alpha lipoic acid in fish feed. The inventors found that it can improve the conversion ratio of feed, promote weight gain, and modulate the gut flora. Additionally, alpha lipoic acid has been found to have antiviral activity against pancreatic disease virus, which can reduce mortality.

Problems solved by technology

The turnover rate may e.g. be affected by the Feed Conversion Rate (FCR) however, it may also be affected by mortality.
There is also a risk that fish will escape due to accidents, e.g.
when shifting nets, or due to bad weather causing wrecked fish pens.
In aquaculture, medicated feed with antibiotics are not applied very frequently due to the fact that diseases spread very quickly and that diseased fish have reduced appetite.
Also, the surplus of medicated feed not eaten by the fish may have a negative impact on the aquatic environment.
Vaccines are widely used, when available, but they are not developed for all diseases.
Furthermore, it has been observed that the use of medication and stress very often results in a negative impact on fish performance.

Method used

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  • Use of alpha lipoic acid as a feed additive for aquatic animals
  • Use of alpha lipoic acid as a feed additive for aquatic animals
  • Use of alpha lipoic acid as a feed additive for aquatic animals

Examples

Experimental program
Comparison scheme
Effect test

example

Example 1

Preparation of Pressed Fish Feed

[0174]The main raw materials are ground and mixed. Microingredients are then added to the mixer and the homogenous mix is conditioned by adding water and steam to the mass in a preconditioner. This starts a cooking process in the starch fraction (the binding component). The mass is fed into a pellet mill. The mass is forced through the mill's die and the strings are broken into pellets on the outside of the die. The moisture content is low and drying of the feed is not necessary.

[0175]Additional oil including a fish feed composition according to the present invention is then sprayed onto the surface of pellets, but as the pellets are rather compact, the total lipid content rarely exceeds 24%. The added oil may be fish oil, microbial / algal or vegetable oils, for example rape seed oil or soy oil, or a mixture of oils. After oil coating, the pellets are cooled in a cooler and bagged. The final pressed fish feed contains 10 to 5000 ppm of the com...

example 2

Method for Preparation of Extruded Fish Feed

[0176]The main raw materials are ground and mixed. Micro ingredients incl. a fish feed composition according to the invention are added to the mixer. The homogenous mix is conditioned by adding water and steam to the mass in a preconditioner.

[0177]Additional oil may also be added to the mass at this stage. This starts a cooking process in the starch fraction (the binding component). The mass is fed into an extruder. The extruder may be of the single screw or the twin-screw type. Due to the rotational movement of the mass in the extruder, the mass is further mixed. Additional oil, water and steam may be added to the mass in the extruder. At the end of the extruder, the mass has a temperature above 100° C. and a pressure above ambient pressure. The mass is forced through the openings in the extruder's die plate. Due to the relief in temperature and pressure, some of the moisture will evaporate immediately (flash off) and the extruded mass be...

example 3

Method for Preparation of Alpha Lipoic Acid Composition in Oil

[0183]Alpha lipoic acid (AL) in the form of a powder is sieved through a 1 mm grid to remove larger particles. A small amount of oil is preheated to 45° C. and mixed with the powder to form a homogeneous liquid paste. The added oil may be fish oil, microbial / algal or vegetable oils, for example rape seed oil or soy oil, or a mixture of oils. More oil is added until the desired concentration is reached. The oil functions as a carrier. This AL composition can be sprayed while stirring to prevent the AL from settling. The composition is used to coat the feed described in examples 1 and 2.

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Abstract

The present invention relates to the use of alpha lipoic acid as feed additive for aquatic animals including fish and shrimp, especially for cold water fish as for example salmon, bream, bass and for warm water fish as for example carp, tilapia, catfish. More particular, this invention relates to the use of alpha lipoic acid for the improvement of the feed conversion ratio and / or daily weight gain in fish, for reducing mortality by regulating the micro flora of the gut and / or by protecting the animal against infections caused by pathogenic viruses.

Description

BACKGROUND OF THE INVENTION[0001]One important factor in aquaculture is the turnover rate. The turnover rate is determined by how fast the fish grow to a harvestable size.[0002]As an example, it takes from 12 to 18 months to raise Atlantic salmon from smolt (the physiological stage when the Atlantic salmon can first be transferred from fresh water to sea water) to harvestable size. A fast turnover has several positive results. First, it helps cash flow. Second, it improves risk management.[0003]The turnover rate may e.g. be affected by the Feed Conversion Rate (FCR) however, it may also be affected by mortality.[0004]It is generally known in the art that the mortality rate increases by an unbalanced microflora and / or by infections caused by pathogenic microbes or viruses. Fish diseases are common, and the likelihood of an outbreak is higher over a long growing period. There is also a risk that fish will escape due to accidents, e.g.[0005]when shifting nets, or due to bad weather cau...

Claims

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Application Information

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IPC IPC(8): A23K20/158A23K50/80A23K20/174A23K40/30A23K20/147A23K20/163A23K40/20A23K40/25A61K31/415A61K31/355A61K47/44
CPCA23K20/158A23K50/80A23K20/174A23K40/30A23K20/147A61K47/44A23K40/20A23K40/25A61K31/415A61K31/355A23K20/163A23K50/00Y02A40/818Y02A40/81
Inventor AASUM, ELISABETHBICKERDIKE, RALPHMARTIN, DAVID CHRISTIANVERLHAC, VIVIANE
Owner DSM IP ASSETS BV
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