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Machine and method for the automatic preparation of substances for intravenous application

a technology of automatic preparation and intravenous application, which is applied in the direction of packaging, pharmaceutical product form change, liquid material, etc., can solve the problems of insufficient and unsatisfactory capacity/preparation speed, low productivity, and no machine known in the prior art for preparing mixtures for intravenous application allows the preparation of paediatric medicines, etc., to achieve improved capacity and preparation speed, improve the speed of substance preparation, and improve the effect of precision

Active Publication Date: 2017-08-17
KIRO GRIFOLS SL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

[0006]An object of the present invention is to disclose a machine with improved capacity and preparation speed compared with that currently known, the dimensions of which are substantially small and which in addition allows medicines to be prepared with greater precision for paediatric purposes. An additional object of the present invention is to disclose a method carried out by said machine which improves the speed of substance preparation compared with the methods known in the prior art.
[0010]The machine according to the present invention has the initial containers and the final containers matrix-like arranged, and beneath said containers has the actuators responsible for removing and inserting the substances in said containers using injectors, preferably syringes, which may have different volumes and degrees of precision. This allows loading and unloading to be carried out with greater or lesser precision in batches using short linear movements from batch to batch, with no circular movements, and so high speed of movement with greater or lesser precision and a small size is made possible as the length of the movements has been reduced.

Problems solved by technology

The machines for preparing mixtures for intravenous application known at present have the drawback of being large, somewhat unergonomic machines with an insufficient and unsatisfactory capacity / preparation speed.
Examples of small machines are also known, but these have very low productivity.
In addition, none of the machines for preparing mixtures for intravenous application known in the prior art allows for the preparation of paediatric medicines, which require more precise measurement of the medicine to be prepared owing to the small volumes of substance mixtures used.

Method used

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  • Machine and method for the automatic preparation of substances for intravenous application
  • Machine and method for the automatic preparation of substances for intravenous application
  • Machine and method for the automatic preparation of substances for intravenous application

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Experimental program
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first embodiment

of the Preparation Zone

[0054]FIG. 2 shows a first embodiment of the preparation zone of the machine according to the present invention. Some elements and / or devices of the machine -1- have been omitted in order to more clearly show the arrangement of the different containers on the tray -4- as well as the arrangement and interaction of the actuators of the different substance metering lines. In this embodiment, as will be explained in more detail below, the metering is carried out using syringes -5- having a piercing point or needle operated by each actuator (-331-, -332-, -333-) of each metering line, respectively. As indicated above, the terms needle or piercing point shall be understood as the tube that is typically made of metal and of small diameter, of which the free distal end is bevel-cut and the other end of which is provided with a bushing that is connected to the distal portion of the barrel of the syringe for the injection, insertion or removal of substances.

[0055]Accord...

second embodiment

of the Preparation Zone

[0074]FIG. 8 shows a second embodiment of the preparation zone of the machine -1- according to the present invention, and in particular a second embodiment of a syringe actuator -6- according to the present invention. Some elements and / or devices have been omitted from the machine -1- to more clearly show the structure of the actuator -6- arranged in a substance metering line along a horizontal guide -60-.

[0075]In this second embodiment, as will be explained in more detail below, metering takes place using syringes -7- having no piercing point, operated by a respective actuator -6- along a horizontal guide -60-. The barrel -71- of each syringe -7- comprises a female-female “Luer-Lock” adaptor -710- arranged on its respective inlet / outlet nozzle, as shown in FIG. 9, for direct connection to / disconnection from the male “Luer-Lock” nozzles of the initial and final containers. In addition, according to this second embodiment, the initial containers may be flasks, ...

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Abstract

A machine and a method are for the automatic preparation of substances for intravenous application. The machine includes a container receiving zone which defines a matrix of individual positions for initial and final containers, and a number of actuators for transferring substances from initial container to final container. Each of the actuators is positioned beneath the zone for receiving initial and final containers, each of the actuators is able to move relatively, independently of the rest of the actuators, and each of the actuators is suitable for receiving and operating injectors with different volumes and degrees of precision in order to remove substances from initial containers and insert them into final containers.

Description

CROSS-REFERENCE TO RELATED APPLICATION[0001]This application claims priority to Spanish Patent Application No. 201530986 filed on Jul. 8, 2015, the disclosure of which including the specification, the drawings, and the claims is hereby incorporated by reference in its entirety.FIELD OF THE INVENTION[0002]The present invention relates to a machine and a method for the automatic preparation of substances for intravenous application.BACKGROUND OF THE INVENTION[0003]Machines for preparing substances for intravenous application are routinely used in hospitals to produce intravenous substance mixtures for application to each patient specifically, to reconstitute said substance from powder and / or to transfer a substance from an initial container, such as a flask or syringe, to the final container, such as a bag or syringe, from which said substance is applied to a line made in the patient, or alternatively a syringe or another flask.[0004]The machines for preparing mixtures for intravenous...

Claims

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Application Information

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Patent Type & Authority Applications(United States)
IPC IPC(8): B65B3/00B65B39/12B65B43/54B65B3/04B65B7/28
CPCB65B3/003B65B3/04B65B39/12B65B43/54B65B7/28A61J3/002B65B7/2828B65B7/2835
Inventor LIZARI ILLARRAMENDI, BORJATELLERIA GARAY, NAIARALIZARRITURRI MARTIARENA, ASIERBARRIO JIMENEZ, ANA BELENILZARBE ANDRES, AMAIAANDRES PINEDA, JOSE IGNACIO
Owner KIRO GRIFOLS SL
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